Source: LINCOLN UNIVERSITY submitted to NRP
QUANTIFYING CROP MANAGEMENT ASSOCIATED VARIABILITY OF THE HEALTH BENEFICIAL GLUCOSINOLATE AND NUTRIENT CONTENT OF COLLARDS (BRASSICA OLERACEA L. ACEPHALA GROUP) IN HYDROPONIC CULTURE
Sponsoring Institution
National Institute of Food and Agriculture
Project Status
ACTIVE
Funding Source
Reporting Frequency
Annual
Accession No.
1030571
Grant No.
2023-38821-40136
Cumulative Award Amt.
$300,000.00
Proposal No.
2022-09963
Multistate No.
(N/A)
Project Start Date
Sep 1, 2023
Project End Date
Aug 31, 2026
Grant Year
2023
Program Code
[EQ]- Research Project
Recipient Organization
LINCOLN UNIVERSITY
820 CHESTNUT ST
JEFFERSON CITY,MO 651023537
Performing Department
(N/A)
Non Technical Summary
Project SummaryVegetables of the family Brassicaceae (Brassica vegetables), which includes collards, possess vitamins, and anti-carcinogenic and antioxidant properties. Brassica vegetables are rich dietary sources of glucosinolates (precursors to a group of anti-carcinogenic isothiocyanates). Collards (Brassica oleraceaL. Acephala) are associated with African American cuisine in the southern U.S., but hydroponic growing allows a more widespread small-scale production of this crop locally under different climates nationwide. In addition to carbohydrates, proteins, and essential minerals the USDA-ARS database reports that 100 g fresh weight of raw collards contains as much as 546.4% of the daily value of vitamin K, which plays a key role in helping the blood to clot and prevent excessive bleeding; vitamin A (8.4% beta-Carotene and 16.7% retinol), 58.8% vitamin C, 8.3% vitamin B6, and 7.6% riboflavin (vitamin B2). This research will utilize current expertise and acquired knowledge from over a decade of hydroponic crop production research at Lincoln University-Missouri to identify crop management-associated variability of health-beneficial glucosinolates in collards. Increased understanding of cropping practices appropriate to produce collards with higher and consistent concentrations of glucosinolates enhances the development of hybrids with improved dietary qualities. Proposed approaches to executing this project involve growing collards in NFT hydroponic culture and extracting leaf-, stem, and root tissue for chemical analysis. Total glucosinolates, vitamin K, and carotenoids will be identified and quantified by gas-liquid chromatography from the products of hydrolysis, isothiocyanates, and oxazolidine,2,thiones. Confirmation of the identity of aglucons from each collard cultivar will be made by a UHPLC/MS/MS tandem system.
Animal Health Component
35%
Research Effort Categories
Basic
55%
Applied
35%
Developmental
10%
Classification

Knowledge Area (KA)Subject of Investigation (SOI)Field of Science (FOS)Percent
70114301020100%
Knowledge Area
701 - Nutrient Composition of Food;

Subject Of Investigation
1430 - Greens and leafy vegetables;

Field Of Science
1020 - Physiology;
Goals / Objectives
Goal 1: Generate data for cultivar selection and subsequent genetic crop improvement of collard greens (Brassica oleracea L. Acephala group) by characterizing pre-harvest crop management induced variation in leaf content of health-beneficial indole (indol-3-ylmethylglucosinolates [glucobrassicin, neoglucobrassicin, and 4-methoxyglucobrassicin]), and aliphatic (3-methylsulfinyl- alkylglucosinolates [glucoiberin and glucoraphanin and sinigrin]) in a commercial hydroponic culture system. Objective (1a): To quantitatively determine plant mineral nutrition induced variations in leaf-, stem, and root content of total and individual indole (indol-3-ylmethylglucosinolates [glucobrassicin, neoglucobrassicin and 4-methoxyglucobrassicin]), and aliphatic (3-methylsulfinylalkylglucosinolates [glucoiberin, glucoraphanin, and sinigrin]) in collard green cultivars under greenhouse hydroponic culture. Objective (1b): Determine cultivar x mineral nutrition interaction effects on the content of health-beneficial indole (indol-3-ylmethylglucosinolates [glucobrassicin, neoglucobrassicin and 4-methoxyglucobrassicin]), and aliphatic (3-methylsulfinylalkylglucosinolates [glucoiberin and glucoraphanin and sinigrin]) in the leaf-, stem, and root of collard greens under greenhouse hydroponic culture. Objective (1c): Assess the quantitative variation in leaf total indole (indol-3-ylmethylglucosinolates) and aliphatic (3-methylsulfinylalkylglucosinolates) in cultivars of collard greens induced by biotic stress (wounding through sequential harvesting of leaves) from greenhouse hydroponic culture. 2. Goal 2: Ascertain statistical correlations between the leaf content of health-beneficial indole and aliphatic glucosinolates and selected dietary nutrients (vitamins A, B, C, D, E, and K) in collard green cultivars grown under greenhouse hydroponic culture.Objective:(2). To examine the statistical associations (correlations) between the leaf total indole (indol-3-ylmethylglucosinolates), aliphatic (3-methylsulfinylalkylglucosinolates), and selected dietary nutrients (vitamins A, B, C, D, E and K) in collard greens cultivars from greenhouse hydroponic culture.
Project Methods
Research Methodologya. Plant culture.For all experiments in this research project, plants will be raised from seed, transferred into NFT culture at the two true-leaf stage, and grown to commercial maturity in a protected hydroponic culture system. Experiments will be conducted in two existing 134 sq.-meter (1,440 sq. ft.) controlled environment hydroponic greenhouses on the Lincoln University-Missouri campus in Jefferson City, using the existing Nutrient Film Technique [NFT] hydroponic system. The NFT modules are representative of standard commercial hydroponic modules used in the hydroponic industry to produce leafy-green vegetables. Collard green leaves will be harvested for growth, yield measurements, and chemical analysis.b. Detailed Approach to Specific Experiments1. Objective (1a).To quantitatively determine plant mineral nutrition induced variations in leaf-, stem, and root content of total and individual indole (indol-3-ylmethylglucosinolates [glucobrassicin, neoglucobrassicin and 4-methoxyglucobrassicin]), and aliphatic (3-methylsulfinylalkylglucosinolates [glucoiberin, glucoraphanin and sinigrin]) in collard green cultivars from hydroponic culture. Two sets of cultivars raised from seed will be transferred into NFT culture. Collard green seedlings will be grown until the bottom four to five leaves from the shoot tip are fully expanded but still tender (commercial maturity) at ambient greenhouse day/night temperature, relative humidity, and photoperiod (natural day/night lighting cycle). Experiments will compare the response of tissue total and individual glucosinolate content and biological yield of collard green grown with three nutrient solution formulations (base Steiner nutrient solution [FERT] treatments). Two of the FERT comprises different concentrations of NaNO3 (2.0 and 5.0 mM) containing a combination of Ca(NO3)2.4H2O and KNO3 (as additional sources of Nitrate-nitrogen (N). The third FERT (control treatment) consists of a modified Steiner base nutrient solution with optimum concentration of Ammoniacal-N as (NH4)2HPO4and (NH4)2SO4plus Ca(NO3)2.4H2O and KNO3as sources of Nitrate-N. Three cycles of NFT experiments will be conducted, each with two sets of cultivars (a '2 x 3' (cultivar x FERT) factorial experiment. Nutrient solution pH, EC, N, K, Ca, Na, and petiole-sap nitrogen concentration data will be collected and used to determine the frequency of refreshing the nutrient solution. Leaves from crops harvested for yield and growth measurement will be sampled for elemental analysis. For organic compound analysis of cultivars, comparative analysis of the leaf-, stem, and root total indole (indol-3-ylmethylglucosinolates) and aliphatic (3-methylsulfinylalkylglucosinolates) will be conducted during the three to four sequential leaf harvesting cycles of each NFT experiment for objective-1(a). Data from all experiments to accomplish objective-1(a) will be analyzed statistically as described in section c below.2. Objectives 1(b).Determine cultivar x mineral nutrition interaction effects on the content of health-beneficial indole (indol-3-ylmethylglucosinolates [glucobrassicin, neoglucobrassicin and 4-methoxyglucobrassicin]), and aliphatic (3-methylsulfinylalkyl-glucosinolates [glucoiberin, glucoraphanin and sinigrin]) in the leaf-, stem, and root of collard greens under greenhouse hydroponic culture. The two collard green cultivars grown to commercial maturity in the three hydroponic nutrient solutions under objective-1(a) above will be sampled and analyzed statistically as a '2 x 3' (cultivar x FERT) factorial experiment. Cultivar x FERT interaction effects will be determined in leaf-, stem-, and root tissue for total glucosinolates indole (indol-3-ylmethylglucosinolates), and aliphatic (3-methylsulfinylalkyl-glucosinolates) content.3. Objectives 1(c).Assess the quantitative variation in leaf total indole (indol-3-ylmethylglucosinolates) and aliphatic (3-methylsulfinylalkylglucosinolates) in cultivars of collard greens induced by biotic stress (wounding through sequential harvesting of leaves) from greenhouse hydroponic culture. The two collard green cultivars will be grown to commercial maturity in the three hydroponic nutrient solutions as described in 1(a) above and will be sampled and analyzed statistically as a '2 x 3' (cultivar x FERT) factorial experiment. Plant tissue will be biochemically analyzed for total indole (indol-3-ylmethylglucosinolates) and aliphatic (3-methylsulfinylalkyl-glucosinolates) glucosinolates content. Biotic stress-induced variation in leaf glucosinolate and dietary nutrient content will be determined from 10 seedling plants of each FERT treatment during the first leaf harvest of each experiment for objective 1a, and in subsequent 4 to 5-week sequential leaf harvesting. Data will be statistically analyzed using the multivariate repeated measures method of the SAS (SAS Institute, Inc., Cary, NC), and as described in Section C below to determine any variability in tissue glucosinolate and dietary nutrient content resulting from sequential harvesting over time, and if the leaf glucosinolate concentrations vary between the first and subsequent sequential harvesting.4. Objective 2.To examine statistical associations (correlations) between the leaf total indole (indol-3-ylmethylglucosinolates), aliphatic (3-methylsulfinylalkylglucosinolates) and selected dietary nutrients (vitamins A, B, C, D, E and K) in collard green cultivars from greenhouse hydroponic culture. This experiment will involve a comparative evaluation to determine associations between the leaf total indole glucosinolates (indol-3-ylmethylglucosinolates), and aliphatic glucosinolates (3-methylsulfinylalkylglucosinolates) content versus the content of dietary nutrients (vitamins A, B, C, D, E, and K) of collard greens grown for objective 1a experiments. Leaves from 10 plants of each treatment will be analyzed for their total and individual content of glucosinolates as well as the dietary nutrients (vitamins A, B, C, D, E, and K). The association between the groups of glucosinolates and the individual dietary nutrients will be determined by correlation analysis using the SAS software (SAS Institute, Cary, NC).c. Experimental Design and Statistical Analysis.Several cropping cycles (as appropriate for objectives 1 through 2), each involving different combinations of cultivars and three nutrient solution formulations (FERT) will be completed in three NFT hydroponic modules. Each module comprises six channels (360 cm long; [rows]) with plants spaced 20 cm apart along the rows. The three modules (blocks) will be divided into three plots with two rows per plot. Each experiment will consist of a randomized complete block (RCB) design with FERT as the main factor (one FERT treatment/block). There will be N = 108 plants per treatment for each of the two cultivars per experiment in a 2 x 3 (cultivar x FERT) factorial experiment. Repeated measures analysis for linear mixed models with normally and non-normally distributed data will be employed for the same response variables above that are obtained from plant samples harvested sequentially using the "Generalized Linear Mixed Model ([GLIMMX]" procedure of SAS as an alternative to the "Method of Least Squares" when it is most applicable. Pair-wise comparisons of Least Squares Means will be conducted with the Tukey-Kramer adjustment, while the Kenward-Roger correction will adjust the standard error estimates and test statistics in PROC GLIMMX. The glucosinolates patterns of the treatments (cultivar x FERT) will be determined as the relative amounts of the total and individual indole glucosinolates (indol-3-ylmethyl-glucosinolates) and aliphatic glucosinolates (3-methylssulfinylalkylglucosinolates) in collards. Cultivars and treatments that exhibit high correlations in their glucosinolate and/or dietary nutrient patterns will be grouped together.

Progress 09/01/23 to 08/31/24

Outputs
Target Audience:The target audiences reached during this reporting period include (1) small-scale limited resource hydroponic crop producers; (2) greenhouse producers of vegetables, herbs, and spices for local farmer's markets; (3) research horticultural scientists & university professors; (4) undergraduate and graduate students of Lincoln and otherUniversitiesand (5) Agricultural Extension Educators; (6)K-12 high school students and teachers. Changes/Problems:No changes to this research project are required currently. However, there has been an ongoing disruption of hydroponic experiments required to accomplish the goals of this research project due to continued delays in implementing structural repairs and renovation to the hydroponic research greenhouses in which all experiments for theproject must be conducted. What opportunities for training and professional development has the project provided?This project enables the training ofone full-time, and one part-time Research Associate in the Cooperative Research Programs Department of Lincoln University to conduct crop plantnutrition and management research in a controlled environment hydroponicsystem and to userelated apparatus, nutrient solution analysis instruments, as well as collect datafrom hydroponic experiments.This projectcurrently has the permission ofthe host institution to train one undergraduate student at Lincoln University. Students working on this project were trained in science-based, crop plantnutrition anduse of hydroponic research tools,instruments,and methods of hydroponic crop production. How have the results been disseminated to communities of interest?Research objectives, methodology, and findings from this and all ongoing research projects weredisseminated to the public (current and prospectivehydroponiccropgrowers) through onsite educational presentations during visits to the hydroponic research center at Lincoln University's George Washington Carver Memorial Research Farm in Jefferson City, Missouri. The center received overtwenty-five visitors during the current reporting period. Training in NFT hydroponic production of collardsand otherhydroponic vegetable production methods was provided to Lincoln University undergraduate students and instructorsof horticulture and plant physiology courses through onsite workshops at the hydroponic research center. What do you plan to do during the next reporting period to accomplish the goals?The Project Director will continue to work towards the achievement ofproject Goal #1 by conductingexperiments designed to accomplish research objective (1a)and initiate experiments to accomplish objective #1b. The project Director willcontinue to process all harvested plant samples, statistically analyze all crop yield and nutrient concentration data obtained,and prepare draft manuscripts for conference presentations and peer-review journal publications.The ongoing education of hydroponics growers, Lincoln University students, K-12 students and teachers, and agricultural audiences about sustainable hydroponic cropproduction and managementwill continue.

Impacts
What was accomplished under these goals? Major activities towards achieving the above goals and objectives. The growth and economic leaf yield of collards (Brassica oleracea L. Acephala group) grown in Nutrient Film Technique (NFT) hydroponic culture with modified Steiner nutrient solution in which the total nitrogen concentration of the culture solution was supplemented with NaNO3 either at 2.0 mM (NaN2) or 5.0 mM (NaN5) sodium (Na) were compared to a Control treatment (no NaNO3 added). The Na concentration of the culture solution was monitored throughout the cropping cycle to determine its contribution from the added NaNO3 compared to Control. The data obtained provided estimates of mean values of leaf count (LC), leaf fresh- and dry weight (LFW; LDW [g]) per plant, and leaf water content (LWC [%]). A leaf organic compound extraction procedure was developed for collards grown in NFT hydroponic culture system. I (a). Crop Culture. The collards cultivar 'Champion' was propagated from seed in slabs of 3.75 × 3.75 × 3.75 cm (1.5" × 1.5" × 1.5": 98 cubes per flat) Rockwool cubes (Grodan Inc., Milton, Canada) in standard horticulture flats (26.68 × 53.34 × 6.35 cm). Seedlings at the second true-leaf stage were transferred into the NFT hydroponic culture and grown to commercial maturity in a 134 sq. meter (1,440 sq. ft.) Controlled Environment Hydroponic Greenhouse at mean ambient day/night temperature of 20.4 ± 7.0/14.0 ± 5.4° C, relative humidity of 62 4 ± 3.2 /50 ± 2.1%, and ambient photoperiod (natural day/night lighting cycle) between 12 December 2023 and 21 February 2024. The experiment compared LC, LFW, and LDW of collards grown with three culture solution formulations of a modified Steiner nutrient solution (FERT). Two of the FERT treatments contained 2.0 mM (NaN2) and 5.0 mM (NaN5) Na, respectively, from NaNO3 supplementation to Ca(NO3)2.4H2O and KNO3 as sources of the total nitrate-nitrogen supply. The third FERT (Control; NaN0) comprised the same modified Steiner nutrient solution with no NaNO3 added (0.2-0.4 mM measured culture solution Na, as an impurity from other reagent salts). The hydroponic culture solution chemistry (pH, EC, N, K, Ca, and Na) was monitored throughout the cropping cycle and used to determine the regularity of culture solution replacement or replenishment with the appropriate sources and volume of macronutrient and micronutrient reagents to optimize growth and yield. Both pH and EC of the nutrient solution were measured twice weekly in situ with the Hanna HI98130 pH/EC/TDS meter (Hanna Instruments, Ltd.), and the pH data was used to guide adjustment of the hydroponic culture solution to the physiological pH (with sulfuric acid) appropriate for nutrient element availability to collards during the cropping cycle. At the end of the cropping cycle, mature fully expanded leaves (commercial maturity) harvested from whole plants of collards were sampled from the three FERT treatments for economic (leaf count and leaf fresh weight), and biological (leaf dry weight) yield determination after drying to constant weight at 75° C (167° F) in an air-forced oven. (b). Key Findings: (Economic & Biological Yield). The LFW, LDW, and LWC of collards positively correlated with increasing culture solution NaNO3 concentration [NaNO3]. Leaf count increased with culture solution [NaNO3] by 5.95% from NaN0 to NaN2, and further by 13.03% at NaN5, but these differences were not statistically significant (p = 0.3278). Both LFW and LDW were increased by NaNO3 supplementation. With LFW, NaN5 was 12.75% > NaN2 (19.13%) > NaN0 (p = 0.0002), and LDW: NaN5 (2.31%) > NaN2 (21.21%) > NaN0 (p < 0.0001). Significantly (p = 0.0148) greater LWC was observed at NaN5 compared to NaN2 and the Control treatment: NaN5 (1.37%) > NaN2 (0.58%) < NaN0 (p < 0.0148). The increased LFW and LWC at higher culture solution NaNO3 concentration (5.0 mM) is consistent with the positive effect of Na on plant cell expansion and water balance of the shoot system. Probable correlations between the observed growth responses to culture solution [NaNO3] and the organic compound composition of collards will be described in subsequent experiments. II. Leaf Sample Preparation and Organic Compound Analysis (a). Leaves of collards harvested in March 2023 were processed to develop organic compound extraction procedure for objective #1a: 'quantitatively determining plant mineral nutrition induced variations in leaf-, stem, and root content of total and individual indole (indol-3-ylmethylglucosinolates [glucobrassicin, neoglucobrassicin and 4-methoxyglucobrassicin]), and aliphatic (3-methylsulfinylalkylglucosinolates [glucoiberin, glucoraphanin and sinigrin]) in collard green cultivars under greenhouse hydroponic culture.' To develop the appropriate organic compound extraction procedure collard green leaves with intact petioles were collected from a pilot study on the third of March 2023, using a factorial sampling approach (3 NFT blocks × 3 rows/block × 3 plants/row × 4 leaves/plant). All samples were placed in labeled storage plastic bags and transported to the laboratory in an ice cooler. In the laboratory individual leaf samples were cleaned, leaf blades were excised from the petioles, folded in labeled aluminum foil pieces, and freeze-dried. Freeze-dried samples were milled, homogenized using Spex SamplePrep™, and stored at -80o C. Development of a sample extraction procedure was completed for this pilot batch by placing two × 100 mg replicates from each powdered leaf sample in a centrifuge tube. Two milliliters of an extraction solution (Acetonitrile-Methanol-Formic acid) was then added to each centrifuge tube, and the resulting extract was stored overnight at 4o C. Subsequently, all extracts were centrifuged at 10,000 G's (98,066.5/square second) for 10 minutes and the supernatant was collected and filtered through a 0.22 µm syringe filter paper. All extracted samples were stored at -80o C for further analysis. (b). Leaf samples of collards from the first NFT experiment, which was established for this project on 12 December 2023 were collected on 17 February 2024. One hundred and forty-four leaf samples were collected from each of the three FERT treatments (NaN5, NaN2, and NaN0) on February 17, 2024. Each FERT treatment was comprised of a three-row block, and four leaves were sampled from each of four plants per row (3 NFT blocks × 3 rows/block × 4 plants/row × 4 leaves/plant factorial sample collection design). All samples were placed in labeled storage plastic bags and transported to the laboratory in an ice cooler. In the laboratory individual leaf samples were cleaned, leaf blades were excised from the petioles, folded in labeled aluminum foil pieces, and freeze-dried. Freeze-dried samples were milled into powder and stored at -80o C for subsequent chemical analysis.

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