Source: TEXAS STATE UNIVERSITY submitted to NRP
BLACK SOLDIER FLY LARVAE (BSFL) AS A PROTEIN SOURCE FOR CATTLE CONSUMING FORAGE
Sponsoring Institution
National Institute of Food and Agriculture
Project Status
COMPLETE
Funding Source
Reporting Frequency
Annual
Accession No.
1025944
Grant No.
2021-67016-34544
Cumulative Award Amt.
$200,000.00
Proposal No.
2020-02682
Multistate No.
(N/A)
Project Start Date
Jul 1, 2021
Project End Date
Jun 30, 2024
Grant Year
2021
Program Code
[A1231]- Animal Health and Production and Animal Products: Improved Nutritional Performance, Growth, and Lactation of Animals
Recipient Organization
TEXAS STATE UNIVERSITY
601 UNIVERSITY DRIVE
SAN MARCOS,TX 78666
Performing Department
(N/A)
Non Technical Summary
Global predictions indicate an increase to nine billion people by 2050, translating to a 58% increase in the demand for meat versus 2010. To meet these food demands, livestock production will increase, placing pressure on natural resources, such as land and water. The production of conventional livestock feeds, such as soy, is associated with significant natural resource inputs. Further, soy competes in the human food and animal feed sectors. As a result of this competition, the demand for (and, thus, price of) soy is expected to increase the price of meat by at least 30% from 2000 to 2050. Ultimately, the environmental and economical impacts of conventional livestock feeds justify identification and evaluation of alternative and potentially more sustainable feeds for beef cattle.We have identified insects, specifically Black Soldier Fly Larvae (BSFL), as a potential replacement for conventional livestock feeds. BSFL have high feed efficiency and can be grown on food and feed byproducts that would otherwise have an economic and environmental cost for disposal. Previous data indicate that production of BSFL is associated with less natural resource inputs than that of conventional feeds. Finally, BSFL are also an attractive livestock feed as consumers in the Western world are not likely to accept insects into their diets, indicating there will not be competition between the feed and food sectors.BSFL have previously been evaluated as feed for fish and chickens. However, they have not yet been evaluated in beef cattle. Accordingly, we will feed different amounts of BSFL to cattle, along with the same amount of a conventional feed, such as soy, to serve as a comparison. We will evaluate how the different supplements impact feed intake and digestibility. We will also conduct a preference study, documenting if cattle express a desire to consume BSFL when presented with BSFL and other conventional feeds as options. Finally, we will use specialized equipment that mimics conditions of cattle's digestive system to evaluate other nutritional characteristics of BSFL in the laboratory. Cumulatively, these research trials will give us insights into how BSFL affects digestion in beef cattle, informing our decision to recommend it as a livestock feed or not.Our long-term goal is to increase the sustainability of beef cattle production. By assessing a novel feed that does not directly compete with existing crop production, is associated with low natural resource inputs, and will not be accepted as a human food, we hope to advance our progress towards achieving this long-term goal.
Animal Health Component
50%
Research Effort Categories
Basic
50%
Applied
50%
Developmental
(N/A)
Classification

Knowledge Area (KA)Subject of Investigation (SOI)Field of Science (FOS)Percent
30233101010100%
Goals / Objectives
Our long-term goal is to increase the sustainability of beef cattle production in the U.S.Objective 1.Assess forage utilization in steers supplemented with graded levels of a novel protein source, defatted Black Soldier Fly Larvae (BSFL)Objective 2.Evaluate if defatted BSFL stimulates forage utilization by steers to a similar extent as an isonitrogenous level of a conventional protein supplementObjective 3.Assess steer acceptance of and preference for defatted BSFL as compared to a conventional protein supplementObjective 4. Determine the site of protein degradability of BSFL usingin vitromodels
Project Methods
Trial 1 is designed as described by Drewery et al. (2014). Five steers fitted with ruminal cannulas will be used in a 5 × 5 Latin square design to determine intake, digestion, and energy availability in response to BSFL supplementation to a low-quality forage diet. A positive control (conventional protein supplement) will be included to facilitate a comparison. Treatments will include four levels of supplemental BSFL: 0, 50, 100, or 150 mg N/kg BW (CON, 50B, 100B, and 150B, respectively) and one level of SBM at 100 mg N/kg BW (100S). Level of supplementation is based on previous experiments in which this range of protein maximized forage utilization of ruminants [Köster et al., 1996; Wickersham et al., 2008; Drewery et al., 2014].Steers will be individually housed in a partially enclosed barn. Low-quality forage will be offered daily at 130% of the previous 5-d average consumption. Prior to feeding, treatments will be dosed ruminally. The five experimental periods will be broken down as follows: 8-d for adaptation to treatment, 5-d for measurement of intake and digestibility, and 1-d for determination of ruminal fermentation parameters and characterization of circulating hormones and metabolitesCalculations of intake and digestion will be made from observations on d 9 through 13. Diet samples will be collected d 9 to 12, feed refusals will be collected d 10 to 13, and fecal grab samples will be collected d 10 to 13. A rumen fermentation profile will be conducted on d 14; immediately before feeding. Rumen fluid will be collected prior to feeding (0 h) and at 4-h intervals for a 24-h period after feeding. A pH meter will be used to measure the pH of each sample at the time of sampling. Subsamples of ruminal fluid will be prepared and frozen at -20°C for determination of volatile fatty acid (VFA) andammonia N. Prior to freezing, 8 mL of rumen fluid will be combined with 2 mL of 25% m-phosphoric acid for VFA and ammonia-N determination..Blood will also be drawn on d 14; plasma will be retained and stored for later determination of urea N.Hay, supplement, feed refusal, and fecal samples will be dried at 55°C in a forced-air oven for 96 h, allowed to air-equilibrate, and weighed to determine partial dry matter. Dried samples will be ground to pass a 1-mm screen then dried at 105°C for dry matter determination. Organic matter will be determined as the loss in dry weight upon combustion for 8 h at 450°C. Nitrogen will be measured by Dumas combustion and crude protein will be calculated as N × 6.25. Analysis for neutral and acid detergent fiber will be performed using an Ankom Fiber analyzer with Na sulfite and amylase omitted and without correction for residual ash. Acid detergent insoluble ash (ADIA) will be determined by sample combustion for 8 h at 450°C. After thawing, rumen fluid samples will be centrifuged at 20,000 × g for 20 minutes. VFA concentrations will be measured with a gas chromatograph. Ammonia N and plasma urea N will be measured with colorimetric procedures using a UV-vis.Trial 2 is designed as described by Van Emon et al. (2015). Steers will be used to determine if ruminants readily consume BSFL as a protein supplement. The study will be a 3 × 6 Latin Square using 3 steers for 6 × 5-d periods. Four dietary treatments will be offered as 6 possible paired combinations. Period breakdown is as follows: a 3-d acclimation period where steers will be supplemented only SBM (CON) and a 2-d experimental period where paired combinations will be offered. Steers will consume a basal diet of forage offered at 130% of the previous 5-d consumption. Dietary treatments will be: 100% SBM (CON); 33% BSFL and 67% SBM (B33); 66% BSFL and 33% SBM (B66), and 100% BSFL (B100). The 6 possible paired combinations will be: CON vs B33, CON vs B66, CON vs B100, B33 vs B66, B33 vs B100, and B66 vs B100.Steers will be housed individually in a partially enclosed barn. Within each pen, there will be a feed bunk divided in half by a barrier. Dietary treatments will be provided in separate removable tubs within each feed bunk to facilitate recording of individual treatment weights. During the acclimation period, steers will be provided CON in equal parts on either side of the divider within the feed bunk. During the experimental period, treatments within each paired combination will be offered on separate sides of the divider. To ensure preference for side of feed bunk is not a confounding factor, the treatments will be offered on opposite sides of the divider on d-4 and -5. Initially, each treatment will be offered at 25% of the prior 3-d consumption rate.To determine preference, bunks will be monitored in 30-min increments and treatment disappearance will be recorded by weighing the removable tubs through 4-h. Treatments will be added as needed during 30-min checks to ensure availability does not limit intake. After the 4-h monitoring period each day, steers will be provided additional SBM (CON) for the remainder of the day. Forage and treatments will be analyzed for nutrients as described for Trial 1.Trial 3In vitrotrue digestibilitywill be quantifiedwith a Daisy® in vitro incubator(Ankom Technology Corp., Macedon, NY) and three ruminally cannulated steers consuming forage and a conventional protein supplement. Rumen fluid will be sampledfrom the cannula 2 h after feeding, filtered through cheesecloth, and mixed with McDougall's buffer at a 1:4 ratio. The Daisy® in vitro incubator will be preset at 39.5°C with an approximate rolling speed of 49 seconds per round. The incubator and sample jars will be purged with 30 seconds of CO2 prior to sample insertion. Approximately 0.5 kg of feedstuff (BSFL, SBM) will be placed into sealed nylon bags and immersed in the incubation solution in sample jars. Four jars with 24 nylon bags each will be placed into the incubator for 0, 6, 12, 24, and 30 h. After incubation, sample bags will be rinsed with water and dried in a forced-air oven at 60°C for 48 h. Analyses for nutrients will be executed as described for Trial 1.

Progress 07/01/21 to 06/30/24

Outputs
Target Audience:-Animal Science faculty and students -General Agriculture faculty and students -Entomology faculty and students -Beef cattle producers -Dairy cattle producers -Insect-rearing industry -American Association of Feed Control Officials (AAFCO) and related feed regulation entities -Food scientists Changes/Problems:The project was delayed due to Covid-19, which caused supply chain breakdowns and other issues that made conducting in-person research difficult. However, we extended the project period one year via a no-cost extension and all project objectives were able to be met without major changes to the original proposal and/or experimental design. In fact, we achieved significantly more than we originally proposed, with additional publications and research being conducted under the scope of BSFL as a novel feed for beef steers. What opportunities for training and professional development has the project provided?This project has provided significant training and professional development. Over the project period, an estimated 20 undergraduates were involved in this research, many of which were paid, but were involved in these research efforts. Many of these undergraduates matriculated into our research lab and continued their own lines of inquiry with a few continuing to graduate school. Further, an estimated 3 graduate students were directly and significantly involved in this research, with others on the periphery. Therefore, skills acquired for students are experimental design, various biological sample collection (rumen fluid, feces), various lab analyses, data collection, data analysis, data interpretation, and scientific writing. As these trials required a concerted team effort, soft skills were also acquired: teamwork, communication, public speaking, and general interpersonal relationships. Finally, this project has set a solid foundation for the Project Director, who is pre-tenure faculty, to establish her research lab and own line of scientific inquiry. She has engaged in significant outreach related to this work and the attention to her lab has positively affected her professional development and establishment of a research agenda. How have the results been disseminated to communities of interest?We have presented findings at several conferences, including those that reach non-agricultural audiences (i.e., the Texas State University and regional 3-minute thesis [3MT] competition). Further, most of the data is already published as mansucripts, conference proceedings, and/or undergraduate and Master's theses. We have also been involved in various podcasts and other interviews that are published in outlets related to feed science and technology, as well as general podcasts related to "out of the box" research that are published by Texas State University. Finally, we have developed infographics and engaging captions that have been published on our lab instagram, which has a following of ~250 accounts and reaches an estimated 425 accounts on a weekly basis. What do you plan to do during the next reporting period to accomplish the goals? Nothing Reported

Impacts
What was accomplished under these goals? Our long-term goal was to increase the sustainability of beef cattle production in the U.S. We aimed to achieve this by conducting multiple evaluations of edible insects as a novel protein source for cattle consuming forage. Our specific objectives and accomplishments are listed below. Objective 1.Assess forage utilization in steers supplemented with graded levels of a novel protein source, defatted Black Soldier Fly Larvae (BSFL) Objective 2.Evaluate if defatted BSFL stimulates forage utilization by steers to a similar extent as an isonitrogenous level of a conventional protein supplement Both of these objectives were addressed through a 5x5 Latin Square design trial, which was published as a manuscript in Journal of Animal Science in 2024. Our data cumulatively indicate that forage utilization was the same between isonitrogenous levels of defatted BSFL and a conventional protein supplement, soybean meal. Further, forage utilization was maximized when we provided 150 mg N/kg BW of BSFL; however, we did not observe the threshold beyond which additional supplementation received diminishing returns. Objective 3.Assess steer acceptance of and preference for defatted BSFL as compared to a conventional protein supplement This objective was addressed in another 5x5 Latin Square design trial, which was also published in the aforementioned manuscript in Journal of Animal Science. Our data indicate that steers had a preference for the conventional protein supplement, cottonseed meal (CSM), as opposed to BSFL or blends of CSM and BSFL. However, the amount of BFSL that they consumed would likely exceed the daily amount that would be offered in a protein supplementation scenario. Thus, in applied settings, the palatability of BSFL would not be a concern for beef cattle and full consumption would likely be observed. Objective 4. Determine the site of protein degradability of BSFL usingin vitromodels We conducted both anin vitroandin situstudy on various edible insect samples, including multiple samples of BSFL, to determine the site of degradability. Although those data have not been published as a manuscript yet, they have been presented at conferences and are publicly available as proceedings and were published as an Undergraduate Honors Thesis, also publicly available. Cumulatively, our data indicate that BSFL has a large portion of rumen degradable protein (RDP), but not as much as SBM or CSM. Thus, the conventional protein supplements may be preferred when protein is provided to cattle consuming low-quality forage to ensure adequate ruminally available N for rumen microbes. However, the degradabilities we did observe indicate that the N in BSFL is highly available to the rumen microbes and host animal, which is positive given the chitin content of BSFL and amount of N that may be inherently bound in chitin. Objective 4. Determine the site of protein degradability of BSFL usingin vitromodels

Publications

  • Status: Published Year Published: 2024 Citation: Tasci KD*, Wickersham TA, Drewery ML. Acceptance and forage utilization responses of steers consuming low-quality forage and supplemented black soldier fly larvae as a novel feed. Journal of Animal Science 2024; 102. https://doi.org/10.1093/jas/skae168
  • Status: Published Year Published: 2024 Citation: Tasci KD*, Wickersham TA, Drewery ML. Acceptance and forage utilization responses of steers consuming low-quality forage and supplemented black soldier fly larvae as a novel feed. Journal of Animal Science 2024; 102. https://doi.org/10.1093/jas/skae168 Status: Published Year Published: 2024 Citation: Carrasco M*, Drewery ML. Mealworm larvae and black soldier fly larvae as novel protein supplements for cattle consuming low-quality forage. Translational Animal Science 2024; 8. https://doi.org/10.1093/tas/txae122
  • Type: Conference Papers and Presentations Status: Published Year Published: 2024 Citation: Carrasco M*, Drewery ML. Mealworm and black soldier fly larvae as protein supplements for beef steers consuming forage. January 2024. Presentation at American Society of Animal Science Southern Section. Louisville, KY. https://doi.org/10.1093/jas/skae019.016
  • Type: Conference Papers and Presentations Status: Published Year Published: 2024 Citation: Dominguez D*, Fukuda EP*, Rea J*, Drewery ML. In situ evaluation of multiple edible insects for cattle. January 2024. Presentation at American Society of Animal Science Southern Section. Louisville, KY. https://doi.org/10.1093/jas/skae019.110


Progress 07/01/22 to 06/30/23

Outputs
Target Audience:-Animal Science faculty and students -General Agriculture faculty and students -Entomology faculty and students -General public -Private sector industry, especially insect producers -American Association of Feed Control Organization Changes/Problems:Covid-19 delayed our ability to conduct the research and analyze all samples, necessitating our reserach for a no-cost extension. What opportunities for training and professional development has the project provided?Undergraduate and graduate student training in reserach development, execution, and dissemination. How have the results been disseminated to communities of interest?We invited the American Association of Feed Control Organization to the thesis defense related to this project and have responded to media inquiries about our project. We have also responded to others who are seeking to conduct similar research and given them direction and provided them with data that have not yet been published. What do you plan to do during the next reporting period to accomplish the goals?Complete sample analysis and submit the publication to a peer-reviewed journal

Impacts
What was accomplished under these goals? We completed sample and data analysis for all measures for Objective 3 and 4. We completed sample and data analysis for all but one measure related to Objectives 1 and 2, which will be conducted in July 2023. This delay is related to the Covid-19 pandemic and inability to source equipment, materials, etc. in a timely fashion, in addition to shortages in labor that cripple external laboratory capabilities and turn-around times. We published a thesis with a peer-reviewed article expected to be submitted in August 2023.

Publications

  • Type: Theses/Dissertations Status: Accepted Year Published: 2023 Citation: Tasci, K. 2023. An in vivo evaluation of defatted Black soldier fly larvae (BSFL) for beef cattle consuming a basal diet of forage. MS thesis. Texas State University, San Marcos, TX. https://digital.library.txstate.edu/handle/10877/16626.
  • Type: Other Status: Published Year Published: 2022 Citation: If people wont eat bugs, maybe cows will? Fast Company. (Online article). July 2022. https://www.fastcompany.com/90765912/if-people-wont-eat-bugs-maybe-cows-will
  • Type: Other Status: Published Year Published: 2022 Citation: Feeding insects to cattle could make meat and milk production more sustainable. The Conversation. (Online article). June 2022. https://theconversation.com/feeding-insects-to-cattle-could-make-meat-and-milk-production-more-sustainable-176223


Progress 07/01/21 to 06/30/22

Outputs
Target Audience:-Animal science faculty and students -Entomology faculty and students -General public -Private sector stakeholders (beef cattle and insect rearing industry) -AAFCO and animal feed regulators Changes/Problems:Our ability to obtain defatted Black Soldier Fly larvae, ruminally cannulated steers, and other reserach itemswas impacted by the Covid-19 pandemic and supply chain breakdown we are still experiencing. Therefore, we are slightly behind on our initially proposed timeline and may need to request a cost extension to ensure all samples are fully analyzed before data analysis is completed. What opportunities for training and professional development has the project provided?Student presentations and attendance at conferences. Student-led execution of research trials. Graduate student training undergraduate students in scientific inquiry and basic research methods. How have the results been disseminated to communities of interest?We have completed many podcasts, radio interviews, and have been the subject of a wide array of press (selected press below). We have also presented at a regional Animal Science conference and published in Animal Science and Entomology peer-reviewed journals. If people won't eat bugs, maybe cows will? Fast Company. (Online article). July 2022. https://www.fastcompany.com/90765912/if-people-wont-eat-bugs-maybe-cows-will Feeding insects to cattle could make meat and milk production more sustainable. The Conversation. (Online article). June 2022. https://theconversation.com/feeding-insects-to-cattle-could-make-meat-and-milk-production-more-sustainable-176223 "Black soldier fly larvae as beef cattle feed - price models". All About Feed. (Online article). February 2022. https://www.allaboutfeed.net/all-about/new-proteins/black-soldier-fly-larvae-as-beef-cattle-feed-price-models/? "PODCAST: Is BSFL a viable cattle feed ingredient?". Feed Strategy. (Audio podcast). June 2021. https://www.feedstrategy.com/feed-strategy-podcasts/podcast-is-bsfl-a-viable-cattle-feed-ingredient/ "Fly larvae as feed with Merritt Drewery". Big Ideas TXST Podcast. (Audio podcast). May 2021. https://news.txstate.edu/inside-txst/big-ideas-podcast/episode-16-fly-larvae-as-feed-with-merritt-drewery.html "Texas State researchers test feeding insect meal to cattle". Feed Strategy. (Online magazine article). April 2021. https://www.feedstrategy.com/animal-nutrition-formulation/texas-state-researchers-test-feeding-insect-meal-to-cattle/ "Fly could be key to reducing carbon footprint of livestock". Spectrum News 1. (Cable and internet news segment). April 2021. https://spectrumlocalnews.com/tx/austin/news/2021/04/24/black-soldier-fly-could-be-key-to-reducing-carbon-footprint-of-livestock "Fly larvae studied as potentially novel livestock feed under USDA grant". San Marcos Corridor News. (Online article). April 2021. https://smcorridornews.com/fly-larvae-studied-as-potentially-novel-livestock-feed-under-usda-grant/ What do you plan to do during the next reporting period to accomplish the goals?Complete data analysis and synthesize results as a Masters thesis and additional peer-reviewed journal article. We may also pursue a standard grant to extend our inquiry and build on preliminary findings through this seed grant.

Impacts
What was accomplished under these goals? We published results from a preliminary trial in a peer-reviewed journal and an economic analysis that was an add-on to this proposal. We conducted both trials described in detail in the proposal that meet Objectives 1-3 and an additional trial that meets Objective 4. Data analysis is not yet complete for the main trial that meets Objectives 1-2.

Publications

  • Type: Journal Articles Status: Published Year Published: 2022 Citation: Fukuda E*, Cox J, Wickersham TA, Drewery ML. Evaluation of Black Soldier Fly larvae (Hermetia illucens) as a protein supplement for beef steers consuming low-quality forage. Translational Animal Science 2022;6(1):1-6. https://doi.org/10.1093/tas/txac018
  • Type: Journal Articles Status: Published Year Published: 2022 Citation: Drewery ML, Liu XP, Wickersham TA. Black Soldier Fly Larvae (BSFL) as a feed for beef cattle: A hedonic pricing model. Journal of Insects as Food and Feed 2022; 8(7):743-751. https://doi.org/10.3920/JIFF2021.0166
  • Type: Conference Papers and Presentations Status: Published Year Published: 2021 Citation: Kathcart EP*, Cox JR, Wickersham TA, Drewery ML. Evaluation of Black Soldier Fly Larvae (BSFL) as a protein supplement for beef steers consuming low quality forage. Western Region American Association of Animal Scientists Conference. October 2021. Poster at Western Region American Association of Animal Scientists Conference. Fort Collins, CO.