Progress 01/05/21 to 12/31/22
Outputs
Target Audience:The target audiences for this conference were: (1) research scientists involved in the production and use of transgenic large animal models for biomedical research; (2) animal scientists interested in the use of new technologies for genetic modification of livestock; (3) representatives from funding agencies (USDA, NIH) that manage grant portfolios supporting development of animal models for biomedical research or genetically modified livestock; and (4) representatives from regulatory agencies (APHIS, USDA; CVM, FDA) that regulate production or use of large animals in biomedical research, and/or genetically modified livestock. Changes/Problems:We had to postpone the meeting twice due to the Covid pandemic. Initially, we moved the summit dates from June 2020 to Sep 2021 and then to June 2022. We have received very positive feedback from the summit participants indicating this conference success. For the 4th conference, we are planning to include a junior member to our organizing committee Dr. Iuri Perisse (USU) to facilitate new ideas/topics. What opportunities for training and professional development has the project provided?We promoted participation of junior investigators, post-doctoral fellows, and graduate students in this meeting by reducing the cost of meeting registration fees for trainees. We also provided travel support for 5 trainees: 4 graduate students and 1 postdoctoral fellow (selected based on their abstracts) whose research uses GE of domestic animals for development of biomedical or agricultural models. To encourage participation of trainees and give their work maximum exposure, the trainees were selected for oral presentations during selected plenary sessions. Additionally, poster presentations were also organized. How have the results been disseminated to communities of interest?The 3rd Large Animal Genetic Engineering (LAGE) Summit was publicized through the International Society of Transgenic Technologies (ISTT) and the International Embryo Technology Society (IETS). The meeting information was also distributed to the relevant NIH institutes (e.g., NICHD, NHLBI, NIAID, NCI) and FDA centers. Announcements with a preliminary program, confirmed speakers and topics was sent out at regular intervals starting in September of 2021. The meeting information and the program were posted at the LAGE Summit webpage http://LAGE.usu.edu and also distributed via mailing list to the previous meeting's participants. The conference proceedings document was distributed to participants and made available to the broader scientific community on the website: https://caas.usu.edu/files/LAGE-2022-proceedings-with-sponsors.pdf What do you plan to do during the next reporting period to accomplish the goals?We are planning to discuss a possibility to co-organize the meeting with the UC Davis group where we would alternate the meeting location between the 2 places. (Park City and Lake Tahoe). We are planning to have our 4th LAGE Summit in June of 2024.
Impacts
What was accomplished under these goals?
The 3rd Large Animal Genetic Engineering Summit took place at the Chateaux Deer Valley in the Wasatch mountains of Park City, Utah from June 5 to 8, 2022. It was a successful conference with a strong scientific program and broad participation from academia, industry and governmental agencies. Over 80 people representing North and South America, Europe and Asia participated in our summit. There were 31 excellent presentations covering gene editing technology development, human disease model development, therapeutic protein production in GE livestock, and applications of the technology in agricultural and biomedical fields. A Regulatory section was also conducted at the summit, which included USDA and FDA perspectives on Agricultural Animal Biotechnology. There were participants from Belgium, Germany, UK, China, Canada and USA.
Publications
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Progress 01/05/21 to 01/04/22
Outputs
Target Audience:The target audiences for this conference were: (1) research scientists involved in the production and use of transgenic large animal models for biomedical research; (2) animal scientists interested in the use of new technologies for genetic modification of livestock; (3) representatives from funding agencies (USDA, NIH) that manage grant portfolios supporting development of animal models for biomedical research or genetically modified livestock; and (4) representatives from regulatory agencies (APHIS, USDA; CVM, FDA) that regulate production or use of large animals in biomedical research, and/or genetically modified livestock. Changes/Problems:We had to postpone the meeting twice due to the Covid pandemic. Initially, we moved the summit dates from June 2020 to Sep 2021 and then to June 2022. We have received very positive feedback from the summit participants indicating this conference success. For the 4th conference, we are planning to include a junior member to our organizing committee Dr. Iuri Perisse (USU) to facilitate new ideas/topics. What opportunities for training and professional development has the project provided?We promoted participation of junior investigators, post-doctoral fellows, and graduate students in this meeting by reducing the cost of meeting registration fees for trainees. We also provided travel support for 5 trainees: 4 graduate students and 1 postdoctoral fellow (selected based on their abstracts) whose research uses GE of domestic animals for development of biomedical or agricultural models. To encourage participation of trainees and give their work maximum exposure, the trainees were selected for oral presentations during selected plenary sessions. Additionally, poster presentations were also organized. How have the results been disseminated to communities of interest?The 3rd Large Animal Genetic Engineering (LAGE) Summit was publicized through the International Society of Transgenic Technologies (ISTT) and the International Embryo Technology Society (IETS). The meeting information was also distributed to the relevant NIH institutes (e.g., NICHD, NHLBI, NIAID, NCI) and FDA centers. Announcements with a preliminary program, confirmed speakers and topics was sent out at regular intervals starting in September of 2021. The meeting information and the program were posted at the LAGE Summit webpage http://LAGE.usu.edu and also distributed via mailing list to the previous meeting's participants. The conference proceedings document was distributed to participants and made available to the broader scientific community on the website: https://caas.usu.edu/files/LAGE-2022-proceedings-with-sponsors.pdf What do you plan to do during the next reporting period to accomplish the goals?We are planning to discuss a possibility to co-organize the meeting with the UC Davis group where we would alternate the meeting location between the 2 places. (Park City and Lake Tahoe). We are planning to have our 4th LAGE Summit in June of 2024.
Impacts
What was accomplished under these goals?
The 3rd Large Animal Genetic Engineering Summit took place at the Chateaux Deer Valley in the Wasatch mountains of Park City, Utah from June 5 to 8, 2022. It was a successful conference with a strong scientific program and broad participation from academia, industry and governmental agencies. Over 80 people representing North and South America, Europe and Asia participated in our summit. There were 31 excellent presentations covering gene editing technology development, human disease model development, therapeutic protein production in GE livestock, and applications of the technology in agricultural and biomedical fields. A Regulatory section was also conducted at the summit, which included USDA and FDA perspectives on Agricultural Animal Biotechnology. There were participants from Belgium, Germany, UK, China, Canada and USA.
Publications
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