Progress 10/01/20 to 09/30/21
Outputs Target Audience:African American students of Central State University High school science students Students attending a STEM high school Human Health & Nutrition Research professionals (Nation wide) Underserved populations who are caught in health inequities Rural populations Exercise Scienc students at undergrduate level Community first responders Changes/Problems:The Project Director is changed to: Dr. Kazi Islam Research Associate Professor of Food, Nutritiona and Health Agricultural Research Development Program (ARDP), Central State University (CSU) Wilberforce, OH 45384; Tel: 973-376-6635; email: kislam@centralstate.edu Dr. Robert Korir with a PhD in food science has been engaged to join the research group to conduct research on microbiological quality of fresh produce in small-scale-farmers production systems (Fields, Greenhouses, Hydroponic, aquaponic), and small food processing plants across the state of Ohio. Microbiological data/results obtained from these research projects will be used to provide food safety training programs and provide microbiological testing services to local produce farmers and food processing industries. The project progress was impeded by COVID-19. The research equipment and supplies were delayed. Even esential items such as handloves were not available for purchasing. Some supplies had to come from overseas and they impacted bu COVID-19 isues. Some of the work was impacted by working from home due to COVID-91. We plan to purchase the foloowing items: Eco-CardioGram (ECG) equipment for testing heart functions of the test rodents pre and post surgery. Confocal Microscope to view cells after staining in 3D. SEA HORSE Equipment for Mitrochondrial analyses in testing specimens. What opportunities for training and professional development has the project provided?Professional development: Student researcher abstracts have been accepted for conference presentation for the upcoming 1890 ARD Research Symposium. Dr. Pratibha Gupta, Attended American Society of Nutrition conference and presented a talk on: "Sleep habit/Sleepiness Questionnaries: A useful tool to identify correlation between sleep, academic performance and obesity promotion in improving health." Current Development of Nutrition. Dr. Korir Attended Farm Science Review Conference at London, Ohio. This conference was based on food safety needs for the farmers at their counties and planned on executing on -farm GAPs (good agricultural practice) and FSMA (food safetyl modernizations act) trainings. How have the results been disseminated to communities of interest?Presentaions to area farmers on "Food is health" at the Second harvest food bank Inaugural Harvest breakfast, Springfield Ohio, September 3, 2021. Presentation in REAP (research education apprenticeship program) for high school students in research training on Nutraceuticals and functional food Clinicalnutrition: Nutritionassessmentlaboratoryduring summer program for school children. Demonstration of Body composition among adults utilizing BIA (Bio electrical impedance) unit for complete body fat analysis to community groups. Routine physical fitnessand promotion of weight management for obesity prevention and body composition. Part of the REAP summer program. Use of Refractometer to test sugar content in various samples of nutritional food, juices, salsa, and salad dressings fruits and, vegetables. Part of the REAP summer program. What do you plan to do during the next reporting period to accomplish the goals?New dimensions in education, exercise, nutrition, and health: To determine how nutrients affect disease development and progression, with the goal of recommending nutrients as potential preventative or treatment options. Determine health enhancing practices which can be incorporated in the agricultural lifestyle to reduce injury and promote overall wellbeing. Engagement of rural populations in interventions, such as mindfulness, to reduce stress related health issues. Two projects over the next two years. A) Engagement of local farmers in health screenings at field days and farming meetings. B) Using mindfulness to alleviate learning disorders and lack of focus among students to enhance retention Development of individual and group nutritional interventions which promote healthy food intake and improve healthy lifestyles. This project includes 6 objectives Objective 1: Prevention of obesity and diabetes type II through application of personalized nutrition and lifestyle interventions including physical activities and nutritional food interventions among minority and under-served populations. Objective 2: Application of vegetarian and plant-based nutrition incorporated with physical activities in maintaining healthy body profile among sedentary adults. Objective 3: Effect of using plants and natural herbs red sanders, cinnamon, fenugreek, bitter melon in controlling and managing diabetes type II: A proteomic study in a diabetic mouse model system. Objective 4: Sleepiness survey questionnaire assessment and study on correlation of sleep deprived adults working in night. Objective 5: Determination of sugar content in commonly consumed food and drinks using refractometer: A tool to test the appropriate sugar intake by diabetics as a precaution. Objective 6: Application of BIA technology to create new standard in complete segmental body composition analysis Determining the effects gasotransmitters such as nitric oxide (NO) and hydrogen sulfide (H2S) in diabetes and cardiovascular disease models including tissue culture, rodents, as well as African Americans (AAs). Research directed at understanding the scientific and consumer community about the safety, efficacy, and/or nutraceutical value of hemp compounds in plant extracts and/or foods through peer-reviewed journal publications, conference presentations, community outreach presentations, incorporation into classroom curricula) At least 1 output in each area will be produced during the stated time period). A food scientist (Dr. Robert Korir) has been engaged in the Food Nutrion and Health group. Overall goal of Dr. Korir's projects to evaluate food microbiological quality of fresh produce in small-scale-farmers production systems (Fields, Greenhouses, Hydroponic, aquaponic), and small food processing plants across the state of Ohio. Microbiological data/results obtained from these research projects will be used to provide food safety training programs and provide microbiological testing services to local produce farmers and food processing industries.
Impacts What was accomplished under these goals?
Self-care prevents the early onset of diabetes.Sleepiness Questionnaires can beuseful tool to identify correlation between sleep, academic performance and obesity promotion in improving health.A significant reduction in perceived stress score and improvement in sleep quality index was noted at the end of a virtual Heartfulness meditation program. Moreover, Heartfulness meditation practice may help cultivate the quality of empathy, acceptance, and individual peace. We conclude that the effects of virtually accessible Heartfulness meditation practice need to be explored further in larger studies. The mindfulness applied research program implemented for undergraduate students at Central State University has had a positive effect on their stress levels being reduced. Diseemination of these successful efoorts are being prepared.My research during the past year focused primarily on manipulation of nutritional intake in order to maintain health. Whether the group was NASA Astronauts, high school field hockey players or firefighters, manipulation of macro and/or micronutrients can help individuals adapt to their stressors and perform at their highest level. A technique to use nitric oxide (NO)therapy to improve blood circulation and heart function has been developed and successfully tried on trials with mice that have heatfailure. This methodlogy/technique is expected to be exapnded to human through clinical trials.Dietary sources of nitric oxide are fresh leafy vegetable, red beets, etc.In addition, NO can produce hydrogen sulfide (H2S) and the best source of H2S is garlic. To maintain a a healthy life it is essential to keep NO/H2S sources in our diets.
Publications
- Type:
Journal Articles
Status:
Submitted
Year Published:
2021
Citation:
Carter, K. Caruso, J. (2021). Dietary Needs, Approaches and Recommendations to meet the Demands of Future Manned Space Flights. Recent Progress in Nutrition
- Type:
Journal Articles
Status:
Under Review
Year Published:
2021
Citation:
Symons, T.B., Roberts, A., Carter, K., Caruso, J. (2021). Lower-limb skeletal muscle power production in female high school field hockey players following high-intensity interval training. Journal of Sports Medicine & Physical Fitness. (In review) (Type: Journal article)
- Type:
Journal Articles
Status:
Under Review
Year Published:
2021
Citation:
Carter, K., Phipps, B. (2021). Does Nutrition Knowledge Affect Obesity in Career Firefighters. ACSMs Translational Journal. (In review) (Type: Journal article)
- Type:
Journal Articles
Status:
Published
Year Published:
2021
Citation:
Kunal Desai, Pratibha Gupta, Priti Parikh and Alpa Desai. (2021). Impact of Virtual Heartfulness Meditation Program on Stress, Quality of Sleep, and Psychological Wellbeing during the COVID-19 Pandemic: A Mixed-Method Study., Int. J. Environ. Res. Public Health 2021, 18(21), 11114; https://doi.org/10.3390/ijerph182111114 - 22 Oct 2021 (Type: Journal article)
- Type:
Book Chapters
Status:
Awaiting Publication
Year Published:
2021
Citation:
Brandy E. Phipps and Craig Schluttenhofer. 2021. Perspectives of industrial hemp cultivation. Industrial Hemp: Food and Nutraceutical Applications. Ed. Milica Poji? and Brijesh Tiwari. Elsevier. (in press) (Type: Invited book chapter) (in press)
- Type:
Journal Articles
Status:
Published
Year Published:
2021
Citation:
Rahib K. Islam, Erinn Donnelly and Kazi N. Islam. (2021). Circulating Hydrogen Sulfide (H2S) and Nitric Oxide (NO) Levels Are Significantly Reduced in HIV Patients Concomitant with Increased Oxidative Stress Biomarkers. J. Clin. Med. 2021, 10, 4460. https://doi.org/10.3390/jcm10194460 (Type: Journal article)
- Type:
Journal Articles
Status:
Published
Year Published:
2021
Citation:
Aran Yoo, MD, Celia Short, MD, Mandi J. Lopez, DVM, MS, PhD, Catherine Takawira, MS, Kazi N. Islam, PhD, Patrick Greiffenstein, MD, FACS, Ian Hodgdon, MD, FACS, Denise M. Danos, PhD, and Frank H. Lau, MD, FACS. (2021) Dehydrated Human Amniotic-Chorionic Membrane Reduces Incisional Hernia Formation in an Animal Model. (Type: Journal article)
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Progress 01/15/20 to 09/30/20
Outputs Target Audience:Fellow researchers through publications in peer reviewed journals. This research, although not specifically land grant type of research, corresponds to Goal 3. Through manipulation of macronutrient intake, it was found that muscle strength could be compromised. This information will be translated to the general population of underserved individuals. Changes/Problems:100% Researcher was added September 1, 2020. This researchers' goals for the next year are: Project 1: Mechanism how nitric oxide therapy benefits diabetes. What opportunities for training and professional development has the project provided?The project provided an opportunity for the PI to become a Fellow of the American College of Sports Medicine. The charge of Fellows is to promote research in the field of health and provide guidance for students and junior researchers. It also allowed the PI to become a member of the Strategic Health Initiative, Women, Sport, & Physical Activity Committee (WSPA) and the ACSM Consumer Outreach Committee. The WSPA committee delves into environmental research that promotes healthy communities. The Consumer Outreach Committee is responsible for translating research into "usable" language for laypersons. This project provided mentorship for an undergraduate student researcher that resulted in (1) abstract publication (2) annual conference presentation and (3) presentation at the 2019-2020 NASA Ohio Space Consortium by the student. This project provided mentorship for an undergraduate student researcher who graduated in May 2020 and is now employed as a Central State University Country Extension Educator. This project provided the opportunity for researchers to attend various conferences (virtually since COVID-19 began) and continuing education webinars related to the project goals. How have the results been disseminated to communities of interest?Projects completed were communicated to national and international audiences through presentations at conferences. Phipps BE. Nutrition and Health Implications of Hemp Metabolites and Grain. Black Farmers: More than 40 Acres and a Mule Conference, Central State University, September 11, 2020. Firefighter Wellness Study: Phase One data was provided to the Fire Chief. 1. Research Study Title: Impact of Heartfulness meditation practices on the burden of stress and sleep disturbances during the time of COVID-19 pandemic related (Video) on the CSU site 2. Fact Sheet prepared Sleep Matters in review 3. Article Diabetes the science behind the disease in review 4. Nutrigenomics Article in review What do you plan to do during the next reporting period to accomplish the goals?Goal 5, Objective 3: Complete analysis for firefighter phase two data, prepare abstracts for submission to conference proceedings and manuscripts for submission to peer-reviewed journals. Complete analysis of corporate wellness nutrition data; prepare abstracts for submission to conference proceedings and manuscripts for submission to peer-reviewed journals. Goal 6, Objective 1: Complete protocol development; complete equipment acquisition. Begin performing experiments.
Impacts What was accomplished under these goals?
Goal 1: Determine effects of storage and processing on nutrient value and oxidation of novel food products and nutrient supplements. Objective 1: Utilization of sea moss in breakfast smoothies and its impact on reaction time and cognition of African American College students. IRB approved protocol is in place. This project is currently on hold due to COVID-19. Objective 2: Measurement of nutritional value of hemp products which have undergone various processing and storage protocols. This is a research collaboration between a Nutrition researcher and Natural Products/Plant Researcher and is on hold awaiting the addition of a Food Science researcher. Goal 2: Develop new or enhance existing intervention strategies for chronic disease or disorder-related symptoms, utilizing exercise protocols. Objective 1: Determine the effect of quantity and quality of sleep on reaction times and cognition of college aged African American individuals. IRB approved protocol is currently in place. This project is currently on hold due to COVID-19. Objective 2: Determine the effect of mindfulness training on Multiple Sclerosis related symptoms. This project currently has IRB approved protocols in place. A pilot study with healthy adults will begin in January. Objective 3: Develop a program for individuals with disabilities which will be held on CSU campus. Protocols for running this program are under development. Goal is to send protocols for outside review January 2021. Objective 4: Compare efficacy of various body composition assessment techniques in different minority/underserved populations. Objective 5: Use of exercise to decrease aberrant behaviors/symptoms which affect quality of life in individuals with disabilities. This project is currently on hold due to COVID-19. Objective 6: Compare efficacy of various nutrient/natural product supplementation in reducing anxiety-related symptoms. MOU/NDA with collaborators in progress. Goal 3: Compare modalities of physical activities and nutrition in underserved populations to develop best practices in changing health behavior. Objective 1: Determine the nutritional knowledge, dietary intake and baseline risk of metabolic syndrome and cardiovascular disease of fire fighters in regional low socioeconomic communities. Initial data has been obtained and is currently being analyzed. Complete. Objective 2: Determine whether goal setting, and use of the self-determination theory will affect the intake of sugared beverages in children in rural areas. IRB is being completed. Goal 4: Development of individual and group nutritional interventions which promote healthy food intake and improve healthy lifestyles. Objective 1: Prevention of obesity and diabetes type II through application of personalized nutrition and lifestyle interventions including physical activities and nutritional food interventions among minority and under-served populations. Objective 2: Application of vegetarian and plant based nutrition incorporated with physical activities in maintaining healthy body profile among sedentary adults. Objective 3: Effect of using plants and natural herbs red sanders, cinnamon, fenugreek, bitter melon in controlling and managing diabetes type II: A proteomic study in a diabetic mouse model system. Objective 4: Sleepiness survey questionnaire assessment and study on correlation of sleep deprived adults working in night shifts office setting and onset of diabetes type II. Completed. Objective 5: Determination of sugar content in commonly consumed food and drinks using refractometer: A tool to test the appropriate sugar intake by diabetics as a precaution. Preliminary protocols done and pilot data is accomplished with the help of students using refractometer. Pilot data collected with 12 different fruits vegetable juice extracts Objective 6: Application of BIA technology to create new standard in complete segmental body composition analysis: comprehensive evaluation of fat mass and abdominal obesity assessment in adults. Pilot testing with BIA is done, small sample data collected with the help of students for IRB proposal. Goal 5: Develop regional nexus for wellness assessment and solutions. Objective 1: Order basic exercise physiology lab equipment such as treadmills, metabolic carts, cycles, and blood analyzers. COMPLETED. Physiology lab equipment has been delivered and faculty trained on their use. Objective 2: Develop standard operating procedures and maintenance schedules for all equipment. Develop emergency procedures for various possible scenarios. Lab manual currently in development. Cholestech Instrument was installed in the FNH lab, with a trial kit to be used for the study and will be used for studies after standardization with a protocol (Protocol is written). Objective 3: Gather pilot data and stakeholder input from various regional communities to determine existing nutrition and wellness needs. Data from initial study currently being analyzed. Firefighter Wellness Study: Phase One Data - Nutrition behavior, physical activity, anthropometric data collected and analyzed. COMPLETE. Phase Two Data - Sleep. Data collected and currently being analyzed. Corporate Wellness Nutrition Study: Data collected (completed June 2020) and currently being analyzed. The study completed on the topic with Wright State University collaboration and data is being evaluated for publication Title: Impact of Heartfulness meditation practices on the burden of stress and sleep disturbances during the time of COVID-19 pandemic
Publications
- Type:
Journal Articles
Status:
Published
Year Published:
2020
Citation:
Baba, S., Smith, T., Hellman, J., Bhatnager, A., Carter, K., Vanhoover, A., Caruso, J. (2020). Space flight-diet induced micronutrient deficiency and response to gravity-free resistive exercise. Nutrients. 12(8): 1-12, DOI: 10.3390/nu12082400.
Vanhoover A.C., McEnroe C.B., Gray W.D., OBrien I.T., Kozerski A.E., Selimovic E.A., Carter, K.A., Stumbo J., and Caruso J.F. (2020). A high protein diet improves exercise performance outcomes to workouts done on gravity-independent hardware. Journal of Exercise and Nutrition, 2(4): 16.
Assessment of Cardiovascular health, Sleep habits, and Diets among college Students by utilizing Public Health Screening Tools, accepted in Journal of Cardiology and current Research JCCR-20-LTR-718 in Press
Sleep Habit/Sleepiness Questionnaires: A use fool tool to identify correlation between sleep ,academic performance and obesity promotion in improving heath. Current Development in Nutrition .2020,Jun: 4(suppl 2):1170.
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