Source: PURDUE UNIVERSITY submitted to
THE SCIENCE AND ENGINEERING FOR A BIOBASED INDUSTRY AND ECONOMY
Sponsoring Institution
National Institute of Food and Agriculture
Project Status
TERMINATED
Funding Source
HATCH
Reporting Frequency
Annual
Accession No.
1017529
Grant No.
(N/A)
Project No.
IND010661R
Proposal No.
(N/A)
Multistate No.
S-1075
Program Code
(N/A)
Project Start Date
Oct 1, 2018
Project End Date
Mar 23, 2021
Grant Year
(N/A)
Project Director
Solomon, KE.
Recipient Organization
PURDUE UNIVERSITY
(N/A)
WEST LAFAYETTE,IN 47907
Performing Department
Ag & Biological Engineering
Non Technical Summary
The processing and production of modern products is often closely linked to petroleum utilization,either as a feedstock or by utilizing petroleum-based chemicals/products. This may be in the form of industrial products such as fuels, lubricants, or chemical products. It is proposed to utilize bio-based materials and processes to replace/supplement petroleum-based products by developing novel applications/products and processes.Our research is focused on developing processes and products to utilize biomaterials to create industrial products and produce efficientprocesses. For example, anti-microbial chemicals are undesirable in food products and high temperatures may decrease the food quality/consumer acceptability.. We have shown thatthe use of room temperature plasma can effectively sterilize various food products without the addition of chemicals or use of high heat. Another example is the use of vegetable oils to replace petroleum in various industrial products. Previously, we have demonstrated the use of plant/animal fats to create cold temperature biofuels and concrete sealants. We are currently exploring the use of plasma as a catalyst tosynthesize lubricants, replacing petroleum as the feedstock.
Animal Health Component
0%
Research Effort Categories
Basic
30%
Applied
60%
Developmental
10%
Classification

Knowledge Area (KA)Subject of Investigation (SOI)Field of Science (FOS)Percent
5015010202040%
4021899202040%
9031899202020%
Knowledge Area
501 - New and Improved Food Processing Technologies; 903 - Communication, Education, and Information Delivery; 402 - Engineering Systems and Equipment;

Subject Of Investigation
1899 - Oilseed and oil crops, general/other; 5010 - Food;

Field Of Science
2020 - Engineering;
Goals / Objectives
Research and develop technically feasible, economically viable and environmentally sustainable technologies to convert biomass resources into chemicals, energy, materials in a biorefinery methodology including developing co-products to enable greater commercialization potential.
Project Methods
Conduct laboratory research involving biomaterials/biomass for conversion to new products/development of new processes.Specifically, we are currently conducting research involving the chemical linkage of DNA to protein molecules to form bioconjugates which are self-aggregating. We are also conducting research involving using high energy, room temperature plasma as a method for sterilization of food products, i.e. fruit juice, semisolid gels, as well as determining the impact on protein structure.Future plans are to explore plasma as catalysts for synthesis of bio-based lubricants and examine the use of microbubble processing to separate low concentration chemicals from the environment.

Progress 10/01/18 to 03/23/21

Outputs
Target Audience:Food Processing/safety Bio-based lubricants Changes/Problems:Dr. Solomon has left Purdue University, therefore we are terminating his project. What opportunities for training and professional development has the project provided?Graduating/graduated 2 PhD students How have the results been disseminated to communities of interest?consulting with industry What do you plan to do during the next reporting period to accomplish the goals? Nothing Reported

Impacts
What was accomplished under these goals? Continued to support bio-based concrete sealant company in Indiana (uses technology developed at Purdue) Research in biodiesel molecular chelation continues to be researched by private company for product development for biofuels/products. New product in roll-out launch currently.

Publications


    Progress 10/01/19 to 09/30/20

    Outputs
    Target Audience:Parties interested in use of room temperatue plasma to sterilize foods, medical equipment, such as fresh produce foods, pre-packaged foods.Benefits are non-chemical, non-thermal sterilization/pasturization of sensitive food products. Potentially interested parties include food processing companies and researchers. Changes/Problems: Nothing Reported What opportunities for training and professional development has the project provided?Trained PhD graduate student How have the results been disseminated to communities of interest? Nothing Reported What do you plan to do during the next reporting period to accomplish the goals?Continue research into how proteins are modified by plasma to determine if alterations can be used to improve/develop new protein-based products.

    Impacts
    What was accomplished under these goals? Our research is focused on developing processes and products to utilize biomaterials to create industrial products and produce efficient processes. For example, anti-microbial chemicals are undesirable in food products and high temperatures may decrease the food quality/consumer acceptability.. We have shown that the use of room temperature plasma can effectively sterilize various food products without the addition of chemicals or use of high heat. We are currently exploring the use of plasma as a catalyst to synthesize lubricants, replacing petroleum as the feedstock.

    Publications

    • Type: Journal Articles Status: Published Year Published: 2020 Citation: Penetration and Microbial Inactivation by High Voltage Atmospheric Cold Plasma in Semi-Solid Material Lei Xu, Ximena Yepez, Bruce Applegate, Kevin M Keener, Bernard Tao & Allen L. Garner Food and Bioprocess Technology volume 13, pages16881702(2020)


    Progress 10/01/18 to 09/30/19

    Outputs
    Target Audience:?Biological engineering scientists Changes/Problems: Nothing Reported What opportunities for training and professional development has the project provided?Graduate PhD eduction How have the results been disseminated to communities of interest?publication in scientific engineering journal What do you plan to do during the next reporting period to accomplish the goals? Nothing Reported

    Impacts
    What was accomplished under these goals? Creating linked different biological molecules (bioconjugates) is a subject of significant interest for biochemistry with applications in biomedical therapies. DNA is difficultto chemically link to large biological molecules such as proteins due to 3 dimensional structure and limited chemical reactivity. Prior studies have required multiple reactions at a differeing pH and temperature conditions. Our work has developed a reaction processat a single temperature and pH to form covalent chemical bonds between DNA and proteins.

    Publications

    • Type: Journal Articles Status: Awaiting Publication Year Published: 2019 Citation: Characterization of covalent crosslinking strategies for synthesizing DNA-based bioconjugates