Progress 10/01/19 to 09/30/20
Outputs
Target Audience:Cattle producers, veterinarians, and other industry stakeholders. Changes/Problems:
Nothing Reported
What opportunities for training and professional development has the project provided?Two non-thesis Master's students, 3 PhD students , and multiple professional students were involved in the completion of these studies. How have the results been disseminated to communities of interest?Results were disseminated through local, regional, and national meetings with industry groups and veterinary professionals. In addition, data were published in the lay press and peer reviewed journals. What do you plan to do during the next reporting period to accomplish the goals?Begin investigations on antimicrobial pharmacology in cattle populations and methods to add value to dairy-beef cross steers. Additional investigations on bovine lameness and its impact on cattle productivity are also planned. A comprehensive description of the epidemiology of respiratory disease in high-risk cattle is underway and will be completed within the next reporting period. Plans to train clinical personnel to serve cattle and small ruminant herds/flocks in rural areas are being developed.
Impacts
What was accomplished under these goals?
This project allowed for the study of the epidemiology of Anaplasma marginale and risk factors for infection with this pathogen in Georgia beef cattle herds. Moreover, this project provided opportunity for the value of different methods of antimicrobial susceptibility testing in Bovine bacterial respiratory pathogens, as well as assisted with the discovery that certain methods of genotyping bacterial strains have more value than others. Furthermore, the project has allowed for the group to better understand how the physiologic and nutritional status of high-risk beef stocker calves impacts risk of respiratory disease. Other opportunities still under investigation include the role of mass medication in selecting for multi-drug resistant bacteria in the bovine airway and the impact of trace mineral supplementation of vaccine responses. Additional investigations have focused on the evaluation of vaccine administration protocols and immune responses in cattle and how effective methods of refrigeration are in maintaining vaccine viability on farm.
Publications
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Progress 10/01/18 to 09/30/19
Outputs
Target Audience:Cattle producers, veterinarians, and other industry stakeholders Changes/Problems:
Nothing Reported
What opportunities for training and professional development has the project provided?Two non-thesis Master's students, 3 PhD students, and multiple professional students were involved in the completion of these studies. How have the results been disseminated to communities of interest?Results were dissimenated through local, regional, and national meetings with industry groups and veterinary professionals. In addition, data were published in the lay press and peer reviewed journals. What do you plan to do during the next reporting period to accomplish the goals?Begin investigations on antimicrobial pharmacology in cattle populations and methods to add value to dairy-beef cross steers. Additional investigations on bovine lameness and its impact on cattle productivity are also planned. A comprehensive description of the epidemiology of respiratory disease in high-risk cattle is underway and will be completed within the next reporting period. Plans to train clinical personnel to serve cattle and small ruminant herds/flocks in rural areas are being developed
Impacts
What was accomplished under these goals?
This project allowed for the study of the epidemiology of Anaplasma marginale and risk factors for infection with this pathogen in Georgia beef cattle herds. Moreover, this project provided opportunity for the value of different methods of antimicrobial susceptibility testing in Bovine bacterial respiratory pathogens, as well as assisted with the discovery that certain methods of genotyping bacterial strains have more value than others. Furthermore, the project has allowed for the group to better understand how the physiologic and nutritional status of high-risk beef stocker calves impacts risk of respiratory disease. Other opportunities still under investigation include the role of mass medication in selecting for multi-drug resistant bacteria in the bovine airway and the impact of trace mineral supplementation of vaccine responses. Additional investigations have focused on the evaluation of vaccine administration protocols and immune responses in cattle and how effective methods of refrigeration are in maintaining vaccine viability on farm.
Publications
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Progress 10/01/17 to 09/30/18
Outputs
Target Audience:Cattle producers and veterinarians Changes/Problems:
Nothing Reported
What opportunities for training and professional development has the project provided?Both a non-thesis Master's student and a PhD student were involved in the completion of these studies. How have the results been disseminated to communities of interest?Results were disseminated through local, regional, and national meetings with industry groups and veterinary professionals. In addition, data were published in the lay press and peer reviewed journals. What do you plan to do during the next reporting period to accomplish the goals?Continue with the previous course of work to further expand the utility of the results obtained thus far.
Impacts
What was accomplished under these goals?
An understanding of the mechanisms of antimicrobial resistance in important respiratory bacteria was gained. In addition, these studies allowed for an improvement in the understanding of the epidemiology and genetic relationships between common respiratory bacteria to be obtained. Moreover, this project provided data on how vaccines impact risk of disease in specific beef cattle populations. Furthermore, the project has allowed for the group to better understand the physiologic status of certain beef calf populations and how this status impacts disease risk.
Publications
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Progress 07/27/17 to 09/30/17
Outputs
Target Audience:Researchers in the scientific community, veterinary clinicians (academic and private practice), and cattle producers Changes/Problems:
Nothing Reported
What opportunities for training and professional development has the project provided?These projects have provided opportunities for training of both veterinary and graduate students. Students in the 2nd and 3rd years of the veterinary curriculum have been intimately involved in these projects. In addition, a Master's of Food Animal Medicine (MFAM) student and several PhD students have participated in these projects as part of their graduate training. How have the results been disseminated to communities of interest?The results of these projects have been disseminated to communities of interest though presentation of the data at local, regional, national, and international meetings. Meetings have involved both veterinary and lay audiences. Much of the work completed during this period will be submitted for publication in peer reviewed journals in the near future. What do you plan to do during the next reporting period to accomplish the goals?Projects to better characterize the epidemiology of resistance in economically important cattle pathogens will continued. In addition, trials to evaluate how reproductive technologies developed by the group will be performed in commercial cattle populations. Evaluating how negative energy balance and dehydration impact risk of bovine respiratory disease will allow the development of novel preventive protocols in high-risk cattle populations.
Impacts
What was accomplished under these goals?
The genomes of a series of Manneheimia haemolytica isolates were sequenced and this work revealed the mechanisms of multi-drug antimicrobial resistance in this important pathogen. In addition, studies were performed that found that lightweight cattle considered to be at high-risk of developing bovine respiratory disease have depressed neutrophil and mononuclear cell function relative to low-risk calf populations. In addition, this same work found that dehydration and fat mobilization were common in high-risk calf populations. Other work performed by the group revolved around the design of more convenient and easier to schedule synchronization program for beef and dairy heifer populations. This work should allow beef and dairy producers to more easily incorporate artificial insemination programs into their herd management plans. A project to determine the seroprevalence of Anaplasma marginale in beef cattle was begun.
Publications
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