Source: UNIV OF MINNESOTA submitted to
FOOD PROTECTION AND DEFENSE: ANIMAL BIOSECURITY
Sponsoring Institution
National Institute of Food and Agriculture
Project Status
TERMINATED
Funding Source
OTHER GRANTS
Reporting Frequency
Annual
Accession No.
1009655
Grant No.
2016-38420-25288
Project No.
MINV-63-121
Proposal No.
2015-10851
Multistate No.
(N/A)
Program Code
KK
Project Start Date
Jun 15, 2016
Project End Date
Jun 14, 2021
Grant Year
2016
Project Director
Rutherford, M.
Recipient Organization
UNIV OF MINNESOTA
(N/A)
ST PAUL,MN 55108
Performing Department
Veterinary Biosciences
Non Technical Summary
This is a training grant that enhances PhD experiential learning in ways that promotes leadership, independent thought, and a deeper understaning of the systems that produce and regulate animal-sourced protein production. Emphasis is placed on strong research skills related to infectious agents and host response.
Animal Health Component
100%
Research Effort Categories
Basic
(N/A)
Applied
(N/A)
Developmental
(N/A)
Classification

Knowledge Area (KA)Subject of Investigation (SOI)Field of Science (FOS)Percent
3113599110050%
3073410110150%
Knowledge Area
311 - Animal Diseases; 307 - Animal Management Systems;

Subject Of Investigation
3599 - Swine, general/other; 3410 - Dairy cattle, live animal;

Field Of Science
1101 - Virology; 1100 - Bacteriology;
Goals / Objectives
Multiple interactions can disrupt access to sufficient food, including natural disasters, economic collapse, human conflict, and, increasingly, infectious agents. Localized outbreaks can result in import/export bans, inflicting losses on producers and limiting many societies' access to animal-sourced proteins. Reducing losses due to disease and contamination must be addressed. These realities substantiate our NNF program Food Protection and Defense: Animal Biosecurity. Our evolving food animal biosecurity sciences require scientists who also understand our complex production systems. Fellowships will support training of three PhD scientists capable of applying their research acumen to improve the production, security, and safety of our animal food chains. Consistent with NNF Goal 1: Science Education, training emphasizes technical aptitude gained from PhD thesis research as well as deeper learning of food production systems, food safety and regulation, food policy, and leadership skills. Through a Food Protection and Defense immersion, exploration of international food animal production systems, and deliberate leadership training, they will gain the applicable communication, teamwork, and project management skills employers increasingly demand. Graduates will be able to immediately translate new knowledge gained from research to emerging problems in food animal biosecurity because they are scientifically astute, can work across disciplines, have practical knowledge of global food systems, can inform policy, and are effective communicators with producers, fellow scientists, and the general public. This will enable PhD graduates to assume leadership positions in which they can conduct novel research and promote both animal-sourced food safety and food security, both nationally and globally.
Project Methods
Trainees will complete a PhD thesis in an area relevant to biosecurity while also completing professional development and experiential learning activities that include externships at the Food Protection and Defense Institute. Transferable skillsets are enhanced via Leadership training, policy development courses, and international food systems explorations.

Progress 06/15/16 to 06/14/21

Outputs
Target Audience:This award supported 3 PhD trainees in the study of infectious disease pathogenesis, transmission, ecology, and biosecurity. The award was for a period of 3 years, applied to their first 3 years of study. Changes/Problems:No changes, students were well into their PhD research when COVID interrupted their training. What opportunities for training and professional development has the project provided?Externships, field experiences, and technical workshops were accessed. In addition, the PhD curriculum provides for seminar preparation and public speaking instruction and experiences, grant writing experiences, and coursework that requires working across disciplines and within teams. Finally, the CVM provides funding for conference attendance. How have the results been disseminated to communities of interest?Via this report to NIFA. What do you plan to do during the next reporting period to accomplish the goals? Nothing Reported

Impacts
What was accomplished under these goals? Three PhD students completed and defended their theses within the grant period. Student A- Female, Hispanic. Thesis title: Epidemiology and genomic characterization of porcine Streptococcus suis. Next Position: Postdoctoral Scientist, University of Minnesota Supercomputing Center. Student B- Female, Veterinarian. Thesis title: A framework for the evaluation of strategies to reduce risk of foot and mouth disease transmission associated with the trade of beef from East African cattle systems: a progressive and participatory approach. Next Position: Field Scientist, Animal Agriculture Systems Team, World Wildlife Fund. Student C- Female, Veterinarian. Thesis title: Epidemiology of Foot and Mouth Disease Virus in Uganda . Next Position: Prevention Effectiveness Fellow, Centers for Disease Control and Prevention.

Publications

  • Type: Journal Articles Status: Published Year Published: 2020 Citation: Adamchick, J, and AM Perez. Choosing awareness over fear: Risk analysis and free trade support global food security. Glob. Food Sec. Sep;26:100445. doi: 10.1016/j.gfs.2020.100445
  • Type: Journal Articles Status: Published Year Published: 2019 Citation: Estrada AA, Gottschalk M, Rossow S, Rendahl A, Gebhart C, Marthaler DG. Serotype and Genotype (Multilocus Sequence Type) of Streptococcus suis Isolates from the United States Serve as Predictors of Pathotype. J. Clin. Microbiol. Aug 26;57(9):e00377-19. doi: 10.1128/JCM.00377-19. Print 2019 Sept. PMID: 31243086
  • Type: Journal Articles Status: Published Year Published: 2020 Citation: Tan S, Dvorak CMT, Estrada AA, Gebhart C, Marthaler DG, Murtaugh MP. MinION sequencing of Streptococcus suis allows for functional characterization of bacteria by multilocus sequence typing and antimicrobial resistance profiling. J. Microbiol. Meth. 169:105871, Feb. 2020.
  • Type: Journal Articles Status: Published Year Published: 2021 Citation: Estrada AA, Gottschalk M, Rendahl A, Rossow S, Marshall-Lund L, Marthaler DG, Gebhart CJ. Proposed virulence-associated genes of Streptococcus suis isolates from the United States serve as predictors of pathogenicity. Porcine Health Manag. 2021 Feb 28;7(1):22. doi: 10.1186/s40813-021-00201-6.
  • Type: Journal Articles Status: Published Year Published: 2020 Citation: Velazquez-Salinas L, Mwiine FN, Ahmed Z, Ochwo S, Munsey A, Lutwama JJ, Perez AM, VanderWaal K, Rieder E. Genetic Diversity of Circulating Foot and Mouth Disease Virus in Uganda Cross-Sectional Study During 2014-2017. Front. Vet. Sci. 2020 Mar 25;7:162. doi: 10.3389/fvets.2020.00162. eCollection 2020.
  • Type: Journal Articles Status: Published Year Published: 2019 Citation: Ochwo S, VanderWaal K, Munsey A, Nkamwesiga J, Ndekezi C, Auma E, Mwiine FN. Seroprevalence and risk factors for lumpy skin disease virus seropositivity in cattle in Uganda. BMC Vet. Res. 2019 Jul 8;15(1):236. doi: 10.1186/s12917-019-1983-9.
  • Type: Journal Articles Status: Published Year Published: 2020 Citation: Ochwo S, VanderWaal K, Ndekezi C, Nkamwesiga J, Munsey A, Witto SG, Nantima N, Mayanja F, Okurut ARA, Atuhaire DK, Mwiine FN. Molecular detection and phylogenetic analysis of lumpy skin disease virus from outbreaks in Uganda 2017-2018. BMC Vet. Res. 2020 Feb 21;16(1):66. doi: 10.1186/s12917-020-02288-5.
  • Type: Journal Articles Status: Published Year Published: 2018 Citation: Abdrakhmanov SK, Tyulegenov SB, Korennoy FI, Sultanov AA, Sytnik II, Beisembaev KK, Bainiyazov AA, Munsey AE, Perez AM, VanderWaal K. Spatiotemporal analysis of foot-and-mouth disease outbreaks in the Republic of Kazakhstan, 1955 - 2013. Transboun. Emerg. Dis. 2018 Oct;65(5):1235-1245. doi: 10.1111/tbed.12864. Epub 2018 Mar 15.
  • Type: Journal Articles Status: Published Year Published: 2019 Citation: Munsey A, Mwiine FN, Ochwo S, Velazquez-Salinas L, Ahmed Z, Maree F, Rodriguez LL, Rieder E, Perez A, VanderWaal K. Spatial distribution and risk factors for foot and mouth disease virus in Uganda: Opportunities for strategic surveillance. Prev. Vet. Med. 2019 Nov 1;171:104766. doi: 10.1016/j.prevetmed.2019.104766. Epub 2019 Sep 5.
  • Type: Journal Articles Status: Published Year Published: 2019 Citation: Mwiine FN, Velazquez-Salinas L, Ahmed Z, Ochwo S, Munsey A, Kenney M, Lutwama JJ, Maree FF, Lobel L, Perez AM, Rodriguez LL, VanderWaal K, Rieder E. Serological and phylogenetic characterization of foot and mouth disease viruses from Uganda during cross-sectional surveillance study in cattle between 2014 and 2017. Transboun. Emerg. Dis. 2019 Sep;66(5):2011-2024. doi: 10.1111/tbed.13249. Epub 2019 Jul 14.
  • Type: Journal Articles Status: Published Year Published: 2018 Citation: Ochwo S, VanderWaal K, Munsey A, Ndekezi C, Mwebe R, Okurut ARA, Nantima N, Mwiine FN. Spatial and temporal distribution of lumpy skin disease outbreaks in Uganda (2002-2016). BMC Vet. Res. 2018 Jun 1;14(1):174. doi: 10.1186/s12917-018-1503-3.
  • Type: Journal Articles Status: Published Year Published: 2021 Citation: Munsey A, Mwiine FN, Ochwo S, Velazquez-Salinas L, Ahmed Z, Maree F, Rodriguez LL, Rieder E, Perez A, Dellicour S, VanderWaal K. Phylogeographic analysis of foot-and-mouth disease virus serotype O dispersal and associated drivers in East Africa. Molec. Ecol. 2021 Aug;30(15):3815-3825. doi: 10.1111/mec.15991. Epub 2021 Jun 10.


Progress 06/15/19 to 06/14/20

Outputs
Target Audience:Three PhD trainees. Changes/Problems:SARS-CoV-2 has impeded travel to several Symposia and conferences. What opportunities for training and professional development has the project provided? Externships, field experiences, and technical workshops were accessed. In addition, the PhD curriculum provides for seminar preparation and public speaking instruction and experiences, grant writing experiences, and coursework that requires working across disciplines and within teams. Finally, the CVM provides funding for conference attendance. How have the results been disseminated to communities of interest? Nothing Reported What do you plan to do during the next reporting period to accomplish the goals?No changes.

Impacts
What was accomplished under these goals? One student has completed training including defense of a PhD dissertation. The remaining students have completed coursework and are on target to defend their disserations in the next few months.

Publications


    Progress 06/15/18 to 06/14/19

    Outputs
    Target Audience:Graduate students Changes/Problems: Nothing Reported What opportunities for training and professional development has the project provided? Externships, field experiences, and technical workshops were accessed. In addition, the PhD curriculum provides for seminar preparation and public speaking instruction and experiences, grant writing experiences, and coursework that requires working across disciplines and within teams. Finally, the CVM provides funding for conference attendance. How have the results been disseminated to communities of interest? Nothing Reported What do you plan to do during the next reporting period to accomplish the goals?Continue as planned- complete thesis research.

    Impacts
    What was accomplished under these goals? All students have completed coursework and additional experiential learning opportunities.

    Publications


      Progress 06/15/17 to 06/14/18

      Outputs
      Target Audience:All students in progress. Changes/Problems: Nothing Reported What opportunities for training and professional development has the project provided? Externships, field experiences, and technical workshops were accessed. In addition, the PhD curriculum provides for seminar preparation and public speaking instruction and experiences, grant writing experiences, and coursework that requires working across disciplines and within teams. Finally, the CVM provides funding for conference attendance. How have the results been disseminated to communities of interest? Nothing Reported What do you plan to do during the next reporting period to accomplish the goals?Continue as planned- complete thesis research.

      Impacts
      What was accomplished under these goals? Students have all selected advisors and passed PhD preliminary exams.

      Publications


        Progress 06/15/16 to 06/14/17

        Outputs
        Target Audience: Nothing Reported Changes/Problems: Nothing Reported What opportunities for training and professional development has the project provided? Externships, field experiences, and technical workshops were accessed. In addition, the PhD curriculum provides for seminar preparation and public speaking instruction and experiences, grant writing experiences, and coursework that requires working across disciplines and within teams. Finally, the CVM provides funding for conference attendance. How have the results been disseminated to communities of interest? Nothing Reported What do you plan to do during the next reporting period to accomplish the goals? Nothing Reported

        Impacts
        What was accomplished under these goals? Students have been recruited, selected, and enrolled in the PhD program.

        Publications