Source: NORTH CAROLINA STATE UNIV submitted to NRP
BIOINFORMATICS CONSULTING AND SERVICE CORE
Sponsoring Institution
State Agricultural Experiment Station
Project Status
COMPLETE
Funding Source
STATE
Reporting Frequency
Annual
Accession No.
1005481
Grant No.
(N/A)
Cumulative Award Amt.
(N/A)
Proposal No.
(N/A)
Multistate No.
(N/A)
Project Start Date
Nov 20, 2014
Project End Date
Sep 30, 2019
Grant Year
(N/A)
Program Code
[(N/A)]- (N/A)
Recipient Organization
NORTH CAROLINA STATE UNIV
(N/A)
RALEIGH,NC 27695
Performing Department
Statistics
Non Technical Summary
The Bioinformatics Consulting and Service Core (BCSC) at NC State offers expertise in analysis of data related to genetics and genomics.It is our goal to create a collaborative relationship that will provide you with software, hardware and analytical support related to bioinformatics, functional genomics and life sciences research. Services are available to all members of the North Carolina State University community, as well as the research community at large.
Animal Health Component
100%
Research Effort Categories
Basic
(N/A)
Applied
100%
Developmental
(N/A)
Classification

Knowledge Area (KA)Subject of Investigation (SOI)Field of Science (FOS)Percent
90173101080100%
Knowledge Area
901 - Program and Project Design, and Statistics;

Subject Of Investigation
7310 - Experimental design and statistical methods;

Field Of Science
1080 - Genetics;
Goals / Objectives
The Bioinformatics Consulting and Service Core (BCSC) at NC State offers expertise in analysis of data related to genetics and genomics.It is our goal to create a collaborative relationship that will provide you with software, hardware and analytical support related to bioinformatics, functional genomics and life sciences research. Services are available to all members of the North Carolina State University community, as well as the research community at large.Analysis support is provided for all areas of genetic and genomic research, including genome and transcriptome assembly,differential expression, metagenomics,genomic screens, sequence alignment, primer design (including methylation studies), comparative genomics, qualitative and quantitative linkage, heritability analysis, segregation, copy number variation, association analysis, and cutting edge data-mining and pathway analysis techniques.The BCSC has the capability to create custom software using a variety of programming languages. The group has and does produce stand-alone software for genetic and genomic analysis, as well as web applications for phenotype and genotype data entry and retrieval. The BCSC also will work closely with the GSL to provide bioinformatics support and analysis for customers gettinghigh-throughput sequencinggenotypedata from the Genome Sciences Laboratory (GSL).
Project Methods
Staff in the BCSC perform analysis using a variety of software tools. They use open source tools provided by the bioinformatics community, and also write their own code in a variety of computing languages. R, python, C++ and Perl are the most commonly used.They rely on the BCSC server to perform the computation needed for the analysis. The BCSC maintains a computing environment that contains multiple compute nodes ranging from 32GB up to768GB of RAM. Our cluster is attached to over200TB of local storage. These are in constant use for statistical analysisand data basing databy the faculty, trainees, staff, and customers of the BCSC. The servers have a full suite of genetic data analysis programs, such as SAS, R, Bowtie, Cufflinks, Samtools, PLINK, Mothur, Trinity, Velvet, MERLIN, Fbat, Pbat, SOLAR, etc.Infrastructure is also available to set up and maintain customized Blastwebsitesolutions.They provide customers with plans of action prior to analysis, and after approved complete the project. After the analysis is completed, they provide results and a written report.