Source: AGRICULTURAL RESEARCH SERVICE submitted to NRP
EXPLORING THE USE OF PROBICON AS A DIRECT-FED MICROBIAL TO REDUCE THE SALMONELLA BURDEN IN MARKET HOGS
Sponsoring Institution
Agricultural Research Service/USDA
Project Status
ACTIVE
Funding Source
USDA INHOUSE
Reporting Frequency
Annual
Accession No.
0441640
Grant No.
(N/A)
Cumulative Award Amt.
(N/A)
Proposal No.
(N/A)
Multistate No.
(N/A)
Project Start Date
Jun 1, 2022
Project End Date
Dec 31, 2023
Grant Year
(N/A)
Program Code
[(N/A)]- (N/A)
Recipient Organization
AGRICULTURAL RESEARCH SERVICE
(N/A)
CLAY CENTER,NE 68933
Performing Department
(N/A)
Non Technical Summary
(N/A)
Animal Health Component
50%
Research Effort Categories
Basic
25%
Applied
50%
Developmental
25%
Classification

Knowledge Area (KA)Subject of Investigation (SOI)Field of Science (FOS)Percent
7113510110050%
7113530110050%
Knowledge Area
711 - Ensure Food Products Free of Harmful Chemicals, Including Residues from Agricultural and Other Sources;

Subject Of Investigation
3530 - Other swine products; 3510 - Swine, live animal;

Field Of Science
1100 - Bacteriology;
Goals / Objectives
Determine the influence of the direct-fed microbial Probicon on swine performance, morbidty and mortality throughout the feeding period. Detect, quantify and isolate Salmonella from the feces of market hogs fed a control diet and a diet including Probicon. Detect, quantify and isolate Salmonella from lymph nodes collected at harvest.
Project Methods
Two groups of market hogs will be enrolled in the study, with 360 market hogs in each group, for a total of 720 market hogs on trial. A total of 36 pens will be used for each group of market hogs, with 12 pens per treatment (10 market hogs per pen), and pen serving as the experimental unit. Thus, there will be 24 total pens per treatment. One of three treatments will be randomly assigned to each pen: control (standard finishing diet), finishing diet supplemented with Bioplus® 2B (the probiotic currently used in swine), and a finishing diet supplemented with Probicon. Market hogs will be enrolled in the study at 60-80 lbs and will remain on trial until ~280 lbs. Feces will be collected at, or prior to, loadout, and market hogs will be followed to the abattoir, where mesenteric lymph nodes will be collected. Salmonella will be detected, enumerated, isolated and characterized from these fecal and lymph node samples.