TOTAL PROANTHOCYANIDIN (PAC) CONTENT AND A-TYPE AND B-TYPE RATIOS OF COMMERCIAL CRANBERRY DIETARY SUPPLEMENTS

• Sponsoring Institution: Agricultural Research Service/USDA
• Project Status: ACTIVE
• Funding Source: USDA COOPERATIVE AGREEMENT
• Reporting Frequency: Annual
• Accession No.: 0435735
• Project Start Date: Aug 31, 2019
• Project End Date: Dec 31, 2022
• Program Code: [(N/A)]- (N/A)

Recipient Organization
INTERNATIONAL CHEMISTRY TESTING
(N/A)
MILFORD,MA 01757

Performing Department
(N/A)

Non Technical Summary
(N/A)

Animal Health Component

75%

Research Effort Categories

Basic

0%

Applied

75%

Developmental

25%

Classification

Knowledge Area (KA)	Subject of Investigation (SOI)	Field of Science (FOS)	Percent
701	5010	1010	100%

Knowledge Area
701 - Nutrient Composition of Food;

Subject Of Investigation
5010 - Food;

Field Of Science
1010 - Nutrition and metabolism;

Keywords

cranberry

proanthocyanidin

hplc

ms

pac

Goals / Objectives
Expanded food composition data and research focused in ongoing ARS programs will be established through small and large studies on the changing composition of the U.S. food supply. Emerging nutrients of public health importance will be studied and data will be included in USDA food and dietary supplement composition databases. For this project, the objectives are to determine total proanthocyanidins (PACs) in cranberry dietary supplements and to determine the fraction of A-type linkages in the PAC dimer and trimer oligomers.

Project Methods
PAC content will be determined in commercial cranberry products using 4-di-methylaminocinnamaldehyde (DMAC) and high performance liquid chromatography (HPLC) methods. ARS will work with ICT to optimize methods of analysis and quality control protocols. Results for PAC content will be compared among methods and laboratories.