Progress 03/01/06 to 02/28/11
Outputs
Progress Report Objectives (from AD-416) The objective of this study is to determine the energy value of resistant maltodextrin, a type of soluble fiber. Approach (from AD-416) A double-blind, randomized controlled trial crossover design will be used to determine the energy value of Fibersol-2 (resistant maltodextrin) compared to that of maltodextrin. Energy value of Fibersol-2 will be determined by combining data from balance measurements and long-term indirect calorimetry. Data from balance (digestion) studies will provide information on the amount of the product energy lost in the feces. Energy lost in the feces represents the major source of lost energy due to the limited digestion/fermentation of fiber. Data from calorimetry studies will provide information on the amount of product energy lost during the digestion and metabolic processes. Combined, these two sets of data provide a complete accounting of the energy budget of the product. This trust agreement was initiated in FY 06 to conduct a study investigating the energy value of soluble fiber and its effect on oxidation, microflora and nutrient interactions. Resistant maltodextrin (RM) is a soluble, nonviscous dietary fiber that is resistant to digestion but fermentable. The metabolizable (ME) and net (NE) energy values derived from nutrient balance studies are unknown. A randomized controlled, double blind, crossover study was conducted with healthy men (n=15) to determine its ME and NE values as well as its impact on the digestibility of other macronutrients. Each subject was assigned to a treatment sequence that consisted of three treatments with controlled diets: 0 g/d RM + 50 g/d maltodextrin, and two levels of dietary RM (25 g/d RM + 25 g/d maltodextrin and 50 g/d RM + 0 g/d maltodextrin). Daily, subjects received their treatment divided into two doses, one was consumed with breakfast and the other with dinner. After a 14-d adaptation period, excreta were collected during a 7-d period. Following the collection period, 24-h energy expenditure was measured. Fecal amount of dry mass, energy, nitrogen, RM, and total carbohydrate increased with increasing dose of RM (P<0.0001). Fat excretion did not differ among treatments. The ME value of RM was 8.2 kJ/g and 10.4 kJ/g, and the NE value of RM was -8.2 kJ/g and 2.0 kJ/g, for the 25 g/d and 50 g/d doses, respectively. RM affected digestive function similarly to other dietary fibers, and these empirical data are important for food labeling regulations related to the energy value of RM. In FY11, a manuscript was submitted for publication and is undergoing review. The results of the study were presented at an international conference on dietary fiber. The sponsor is working with U.S. FDA to change the energy value of the ingredient based on our results. Activities and progress of this Agreement were monitored through site visits, conference calls, and email correspondence.
Impacts
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Progress 10/01/09 to 09/30/10
Outputs
Progress Report Objectives (from AD-416) The objective of this study is to determine the energy value of resistant maltodextrin, a type of soluble fiber. Approach (from AD-416) A double-blind, randomized controlled trial crossover design will be used to determine the energy value of Fibersol-2 (resistant maltodextrin) compared to that of maltodextrin. Energy value of Fibersol-2 will be determined by combining data from balance measurements and long-term indirect calorimetry. Data from balance (digestion) studies will provide information on the amount of the product energy lost in the feces. Energy lost in the feces represents the major source of lost energy due to the limited digestion/fermentation of fiber. Data from calorimetry studies will provide information on the amount of product energy lost during the digestion and metabolic processes. Combined, these two sets of data provide a complete accounting of the energy budget of the product. This trust agreement was initiated in FY 06 to conduct a study investigating the energy value of soluble fiber and its effect on oxidation, microflora and nutrient interactions. Resistant maltodextrin (RM) is a soluble, nonviscous dietary fiber that is resistant to digestion but fermentable. The metabolizable (ME) and net (NE) energy values derived from nutrient balance studies are unknown. A randomized controlled, double blind, crossover study was conducted with healthy men to determine it�s ME and NE values as well as its impact on the digestibility of other macronutrients. The ME value of RM was 8.2 kJ/g and 10.4 kJ/g, and the NE value of RM was -8.2 kJ/g and 2.0 kJ/g, for the 25 g/d and 50 g/d doses, respectively. RM affected digestive function similarly to other dietary fibers, and these empirical data are important for food labeling regulations related to the energy value of RM. In FY10, the final year of the project, a manuscript was submitted for publication and is undergoing review. The results of the study were presented at an international conference on dietary fiber. The sponsor is working with U.S. FDA to change the energy value of the ingredient based on our results. Activities and progress of this Agreement were monitored through site visits, conference calls, and email correspondence.
Impacts
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Progress 10/01/08 to 09/30/09
Outputs
Progress Report Objectives (from AD-416) The objective of this study is to determine the energy value of resistant maltodextrin, a type of soluble fiber. Approach (from AD-416) A double-blind, randomized controlled trial crossover design will be used to determine the energy value of Fibersol-2 (resistant maltodextrin) compared to that of maltodextrin. Energy value of Fibersol-2 will be determined by combining data from balance measurements and long-term indirect calorimetry. Data from balance (digestion) studies will provide information on the amount of the product energy lost in the feces. Energy lost in the feces represents the major source of lost energy due to the limited digestion/fermentation of fiber. Data from calorimetry studies will provide information on the amount of product energy lost during the digestion and metabolic processes. Combined, these two sets of data provide a complete accounting of the energy budget of the product. Significant Activities that Support Special Target Populations This agreement was initiated in FY 2006 to conduct a study investigating the energy value of soluble fiber and its effect on oxidation, gut microflora, and nutrient interactions. The dietary intervention phase of the study was completed in FY 2007. In FY 2009, analyses were completed and a manuscript was finalized for submission to a peer-reviewed journal. Activities and progress of this agreement were monitored through site visits, conference calls, and E-mail correspondence.
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Progress 10/01/07 to 09/30/08
Outputs
Progress Report Objectives (from AD-416) The objective of this study is to determine the energy value of resistant maltodextrin, a type of soluble fiber. Approach (from AD-416) A double-blind, randomized controlled trial crossover design will be used to determine the energy value of Fibersol-2 (resistant maltodextrin) compared to that of maltodextrin. Energy value of Fibersol-2 will be determined by combining data from balance measurements and long-term indirect calorimetry. Data from balance (digestion) studies will provide information on the amount of the product energy lost in the feces. Energy lost in the feces represents the major source of lost energy due to the limited digestion/fermentation of fiber. Data from calorimetry studies will provide information on the amount of product energy lost during the digestion and metabolic processes. Combined, these two sets of data provide a complete accounting of the energy budget of the product. Significant Activities that Support Special Target Populations This Trust Agreement was initiated in fiscal year (FY) 2006 to conduct a study investigating the energy value of soluble fiber and its effect on oxidation, microflora, and nutrient interactions. The dietary intervention was completed in FY 07. Analyses have been completed and a manuscript is being prepared. Activities and progress of this Agreement were monitored through site visits, conference calls, and email correspondence.
Impacts
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Progress 10/01/06 to 09/30/07
Outputs
Progress Report Objectives (from AD-416) The objective of this study is to determine the energy value of resistant maltodextrin, a type of soluble fiber. Approach (from AD-416) A double-blind, randomized controlled trial crossover design will be used to determine the energy value of Fibersol-2 (resistant maltodextrin) compared to that of maltodextrin. Energy value of Fibersol-2 will be determined by combining data from balance measurements and long-term indirect calorimetry. Data from balance (digestion) studies will provide information on the amount of the product energy lost in the feces. Energy lost in the feces represents the major source of lost energy due to the limited digestion/fermentation of fiber. Data from calorimetry studies will provide information on the amount of product energy lost during the digestion and metabolic processes. Combined, these two sets of data provide a complete accounting of the energy budget of the product. Significant Activities that Support Special Target Populations This report documents research conducted under a trust agreement between ARS and Matsutani, Ltd. Additional details of research can be found in the report for the in-house associated project 1235-51530-008-00D, "Dietary Modulation of Markers of Inflammation and Oxidation as Risk Factors of Chronic, Degenerative Diseases." This trust agreement was initiated in FY06 to conduct a study investigating the energy value of soluble fiber and its effect on oxidation, microflora, and nutrient interactions. The dietary intervention was completed in FY07. Sample processing was completed and analyses are ongoing. Activities and progress of this agreement were monitored through site visits, conference calls, and email correspondence.
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Progress 10/01/05 to 09/30/06
Outputs
Progress Report 4d Progress report. This report serves to document research conducted under a Trust Agreement between ARS and Matsutani. Additional details of research can be found in the report for the parent project 1235-51530-007-00D, "Dietary modulation of markers of inflammation and oxidation as risk factors of chronic, degenerative diseases." This Trust Agreement was initiated in FY 06 to conduct a study investigating the energy value of soluble fiber and its effect on fat oxidation. The dietary intervention is planned to begin in FY 07. During FY 06, protocol and menu development was begun.
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