Progress 09/27/04 to 04/30/07
Outputs
Progress Report Objectives (from AD-416) The objective of this cooperative research project is to understand the genetic basis of mycotoxin production and pathogenicity for the wheat and barley scab fungus and to use genomics to develop an information-based program for disease control combining genomic information from wheat and barley as well as the pathogenic fungus. Approach (from AD-416) 1) To conduct base-line microarray experiments and 2) To gather functional genomic data by way of mutagenesis to provide information to benefit scab control for both the short and long term. Significant Activities that Support Special Target Populations This report serves to document research conducted under a SCA between ARS and Purdue University. Additional details of this research can be found in the report for parent project 3640-22000-022-00D, Pathogen Population Biology and Genomics, and Host Resistance for Fusarium Head Blight of Cereals. Monitoring activities of the subordinate project included quarterly telephone calls between investigators. With funding provided by the USDA CSREES, NRI we have identified gene expression in the fungus as it develops from a resting spore to a fully infectious fungal mycelium. The expression levels of thousands of fungal genes were monitored over time. We are currently creating mutations in several identified genes seeking to determine their function and role in spore germination. By learning the mechanisms that trigger spore germination we may be able to interfere with this process, providing a new strategy for disease control.
Impacts
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Progress 10/01/05 to 09/30/06
Outputs
Progress Report 4d Progress report. This report serves to document research conducted under a specific cooperative agreement between ARS and Purdue University. Additional details of this research can be found in the report for parent project 3640-22000-022-00D - Pathogen Population Biology and Genomics, and Host Resistance For Fusarium Head Blight of Cereals. With funding provided by the USDA CSREES, NRI we have identified gene expression in the fungus as it develops from a resting spore to a fully infectious fungal mycelium. The expression levels of thousands of fungal genes were monitored over time. We are currently creating mutations in several identified genes seeking to determine their function and role in spore germination. By learning the mechanisms that trigger spore germination we may be able to interfere with this process, providing a new strategy for disease control.
Impacts
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Progress 10/01/04 to 09/30/05
Outputs
4d Progress report. This report serves to document research conducted under a specific cooperative agreement (agreement number 58-3640-2-139) between ARS and Purdue University. Additional details of research can be found in the report for the parent CRIS 3640-22000-022-00D Pathogen Population Biology and Genomics, and Host Resistance for Fusarium Head Blight of Cereals. With funding provided by the USDA CSREES, NRI we have profiled gene expression in the fungus as it develops from a resting spore to a fully infectious fungal mycelium. The expression levels of over 7000 fungal genes were monitored over time in hope of identifying those genes critical for this developmental event in the hope of discovering way to interfere with germination in order to prevent disease initiation.
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