DETERMINATION OF LEISHMANIA INFANTUM INFECTION RATES IN UNITED STATES FOXHOUNDS AND NEAPOLITAN MASTIFFS AND SURVEY OF RISCK FACTORS

• Sponsoring Institution: Cooperating Schools of Veterinary Medicine
• Project Status: REVISED
• Funding Source: STATE
• Reporting Frequency: Annual
• Accession No.: 0217638
• Project Start Date: Feb 1, 2010
• Project End Date: Jan 31, 2011
• Program Code: [(N/A)]- (N/A)

Recipient Organization
IOWA STATE UNIVERSITY
S. AND 16TH ELWOOD
AMES,IA 50011

Performing Department
Veterinary Medicine

Non Technical Summary
Leishmania infantum is a fatal zoonotic disease in which dogs serve as a domestic reservoir for human disease. We have ongoing canine disease in this country. It is important to determine what is leading to these infections and the level of risk to humans.

Animal Health Component

100%

Research Effort Categories

Basic

(N/A)

Applied

100%

Developmental

(N/A)

Classification

Knowledge Area (KA)	Subject of Investigation (SOI)	Field of Science (FOS)	Percent
722	3830	1170	100%

Knowledge Area
722 - Zoonotic Diseases and Parasites Affecting Humans;

Subject Of Investigation
3830 - Pets (companion animals);

Field Of Science
1170 - Epidemiology;

Keywords

canine

protozoa

leishmania

polymerase chain reaction

serology

Goals / Objectives
We did surveillance of L. infantum infection in several different dog breeds to help determine what the risk factors are to PCR positive and seropositive disease.

Project Methods
We used routine blood draws of dogs and quantitiative PCR as well as serology to determine the infection status and disease progression of each dog.