Source: THE UNIVERSITY OF TEXAS AT AUSTIN submitted to NRP
TRACE ELEMENTS IN DIET, NUTRITION AND HEALTH: ESSENTIALITY AND TOXICITY
Sponsoring Institution
National Institute of Food and Agriculture
Project Status
COMPLETE
Funding Source
Reporting Frequency
Annual
Accession No.
0210877
Grant No.
2007-35200-18235
Cumulative Award Amt.
$10,000.00
Proposal No.
2007-02296
Multistate No.
(N/A)
Project Start Date
Jul 15, 2007
Project End Date
Jul 14, 2008
Grant Year
2007
Program Code
[31.0]- (N/A)
Recipient Organization
THE UNIVERSITY OF TEXAS AT AUSTIN
101 EAST 27TH STREET STE 4308
AUSTIN,TX 78712-1500
Performing Department
(N/A)
Non Technical Summary
Morbidity and mortality related to trace element deficiencies or toxicities may affect more than half of the world's population. Thus, this international scientific conference will help researchers, nutritionists, agricultural providers and policymakers integrate trace element knowledge into research and food, agriculture and health policies.
Animal Health Component
50%
Research Effort Categories
Basic
50%
Applied
50%
Developmental
(N/A)
Classification

Knowledge Area (KA)Subject of Investigation (SOI)Field of Science (FOS)Percent
70260101010100%
Goals / Objectives
The objective of this conference on Trace Elements in Diet, Nutrition and Health: Essentiality and Toxicity is to disseminate findings of new research and encourage collaboration of scientists across international boundaries.
Project Methods
New research findings and information will be exchanged through 12 symposia (four of which are plenary sessions), 3 poster presentations, and 10 oral minisymposia. Thirty-nine invited speakers will present overviews of recent research. Oral minisymposia and poster sessions will be selected from investigator-submitted abstracts. All presentations will be followed by open discussion.

Progress 07/15/07 to 07/14/08

Outputs
OUTPUTS: The objective of this conference on Trace Elements in Diet, Nutrition and Health: Essentiality and Toxicity was to disseminate findings of new research and encourage collaboration of scientist across international boundaries. The location of the conference was Crete, Greece in October, 2007. New research findings and information were exchanged through 12 symposia (four which were plenary sessions), three poster presentations (totaling 160 posters), and 13 oral minisymposia (totaling 72). Fifty invited speakers presented overviews of recent research. All presentations were followed by open discussion. A total of 277 abstracts was published in 2008 as a supplement to the research journal, Cell Biology and Toxicoloy. A total of 42 manuscripts submitted by invited speakers were published in four groups as additions to the regular issues of the same journal, Cell Biology and Toxicology (two groups in 2008; the remaining two groups are in press). Topics of plenary sessions were: Mediterranean diet, traditional foods and health, Trace minerals: modulators of arterial function, Zinc nutriture and fetal origins of disease, Trace element nutrition and dietary recommendations, Trace element speciation, and Trace element deficiencies. Topics of symposiums were: Copper in neurologic and neurodengerative diseases, Health effects and low dose exposure to toxic metals, Environmental stress and mineral homeostasis, Molecular mechanisms of metal induced disease, Mineral elements and molecular signaling as it relates to human disease, Is copper involved in carcinogenesis/carcinostatics, Advances in analytical detection of trace elements in biological tissues, and Zinc and the common cold. Categories of mini-symposiums (with related posters) were: Trace element intakes, dietary patterns, bioavailability, and tissue distributions; Cancer and oxidative stress; Anemias, and cardiovascular and pulmonary diseases; Diabetes mellitus, metabolic syndrome X, and obesity; Disorders of aging; Fetal development and pediatric disorders; Infectious diseases and immune disorders; Molecular nutrition for the clinician; Osteoporosis and other bone disorders; Neurological diseases and neuropsychological impairment; Toxicity of trace elements; Trace element detection and quantification; and Role of micronutrients (iodine, iron and zinc) in intellectual development. PARTICIPANTS: Additional speakers: Lindsay Allen USDA, ARS (Davis, CA, USA) International dietary standards for trace elements; Lars Barregard Sahlgrenska University(Gothenburg, Sweden) Neurological and renal effects of low dose exposure to elemental mercury exposure from amalgam in children; Maria-Luisa Carvalho, Jose Rebocho University of Lisbon (Lisbon, Portugal) X-ray fluorescence technique on trace element determination in biological samples; Bruce Fowler, Elizabeth Conner, Hiroshi Yamauchi, Gensheng Wang ATSDR (Atlanta, GA, USA); NIH/NCI (Bethesda, MD, USA); Kitasato University (Kitasato, Japan); MD Anderson(Houston, TX, USA) Proteomic and metabolomic biomarkers for assessing low dose toxic trace element interactions: an overview; YanHong Gu and Hiroko Kodama National Research Institute for Child Health and Development; Teikyo University School of Medicine (Tokyo, Japan) Possible association of wilson's disease with hepatocellular carcinoma; Edouard Jallot Laboratoire de Physique Corpusculaire (Aubiere, France) Ion and electron beams methods for biological trace element characterisation at bioceramics/cells interface; Taiyi Jin School of Public Heelth, Fudan University (Shanghai, China) Factors influencing dose-response relationships of cadmium in humans - diabetes, metallothionein and metallothionein antibodies; Y. James Kang University of Louisville (Louisville, KY, USA) Arsenic cardiomyopathy and molecular mechanism; Maria Kapsokefalou, Konstantina Argir Agricultural University of Athens (Athens, Greece); Agricultural Universiy of Athens (Athens, Greece) Predicting relative concentrations of bioavailable iron using in vitro approaches; Kristi Lew, Jason Acker, Chris Le University of Alberta (Edmonton, Canada) Arsenic biomonitoring in children playing on chromated copper arsenate-treated playgrounds; Ying Lu,Spiros Pergantis University of Crete (Heraklion, Greece) Purification and identification of low molecular fraction of selenium species in liver cytosol by high performance liquid chromatography and tandem mass spectrometric techniques; Alvaro Puga, Li Peng, Michael Schnekenburger Reprogramming of histone marks by chromium University of Cincinnati (Cincinnati, OH, USA). Deleted speakers: Melinda Beck University of North Carolina, School of Medicine (Chapel Hill, NC, USA) Host selenium status: influence on immune function and viral pathogenesis; Andreas Karydas Institute of Nuclear Physics, Dimocritos (Athens, Greece) Trace element detection: nutritional applications; Bibudhendra Amu Sarkar University of Toronto (Canada) Environmental challenges of arsenic poisoning in south Asia; Mihaly Szilagyi Research Institute for Animal Breeding and Nutrition (Herceghalom, Hungary) Current understanding of dietary interactions that determine biological availability of trace elements; Michel Thellier University of Rouen (Rouen, France) Current challenges in trace element detection in biological tissues; Tao Wang Peking University Health Science Center (Bejing, China) Epidemiological study on copper and carcinogenesis. Six students were given travel grants of $600 for the conference. Of these, $1,000 was contributed by this USDA grant. TARGET AUDIENCES: Nothing significant to report during this reporting period. PROJECT MODIFICATIONS: Nothing significant to report during this reporting period.

Impacts
This conference was the first time that the regularly scheduled individual meetings of The International Society for Trace Element Research in Humans (ISTERH), the Hellenic Trace Element Society (HTES) and the Nordic Trace Element Society (NTES) were combined to create a joint conference to foster scientific exchange on trace elements. It involved scientists from 52 countries. This meeting explored the relationship of trace elements to diet, nutrition and health in terms of essentiality and toxicity. It incorporated all aspects related to these minerals, such as international dietary recommendations, innovative methods of detection, and deficiency and toxicological effects. The focus was relevant to the US food system as trace elements are bioactive compounds in our food supply that can dramatically affect human health. Individuals connected with this meeting were from the following countries: Australia, Austria, Belarus, Brazil, Cameroon, Canada, Chile, China, Croatia, Czech Republic, England, Finland, France, Georgia, Germany, Greece, Hungary, India, Islamic Republic of Iran, Israel, Italy, Jamaica, Japan, Kenya, Republic of Korea (South), Latvia, Lithuania, Mexico, Montenegro, Morocco, New Zealand, Norway, Pakistan, Poland, Portugal, Romania, Russian Federation, Serbia, Slovak Republic, Slovenia, Spain, South Africa, Sweden, Switzerland, Thailand, The Netherlands, Tunisia, Turkey, Ukraine, United Arab Emirates, United States, and Venezuela. Thus, the proposed conference was truly international and provided an excellent forum that fostered scientific exchange. Resources provided by the U.S. Department of Agriculture were utilized to provide a student travel grant, registrations for two US scientists, travel and subsistence for one US scientist, partial printing of conference abstracts and proceedings; and partial audiovisual support. In sum, this conference was a unique opportunity for our scientists to disseminate new research, become up-dated on current knowledge concerning trace elements, and develop collaborations across international boundaries. The information obtained from this conference will help researchers, agricultural provides and policy makers integrate trace element knowledge into research and food, agriculture and health policies.

Publications

  • Wasowicz, W. 2008. Are people with low selenium and antioxidant status at much higher risk of cancer Cell Biology and Toxicology. 24(S1):S31-32.
  • Tinggi, U., Sadler, R., Noller, B., Seawright, A., Ng, J., Moore, M., Cooper, K., Golding, G., Olszowy, H., and Scheelings, P. 2008. Study of the bioavailability and toxicity of arsenic and mercury in Chinese proprietary medicines (CPM) using an animal model. Cell Biology and Toxicology. 24(S1):S12.
  • Tokalioglu, S., and Kartal, S. 2008. Synthesis and application of a new chelating resin functionalized with salicylaldoxime for the determination of Pb(II), Ni(II), Cu(II) and Mn(II) ions in water samples by flame atomic absorption spectrometry. Cell Biology and Toxicology. 24(S1):S101.
  • Toman, R., Babikova, L., Golian, J., Massanyi, P., Hluchy, S., Lukac, N., Stawarz, R., Formicki, G., and Cupka, P. 2008. Effect of nickel on the testicular and epididymal structure and its distribution in the rat organism after an experimental administration. Cell Biology and Toxicology. 24(S1):S85-86.
  • Trichopoulou, A. 2008. Mediterranean diet, traditional foods and health: critical components and mediating mechanisms. Cell Biology and Toxicology. 24(S1):S108.
  • Francesconi, K.A. 2008. Studies on the biotransformation of arsenic and selenium in humans. Cell Biology and Toxicology. 24(S1):S112.
  • Fujiwara, J., Shimizu, N., Hemmmi, H., and Aoki, T. 2008. Molecular diagnosis for atypical patients and carriers with Wilson disease. Cell Biology and Toxicology. 24(S1):S58.
  • Fujiwara, N., Iso, H., Kitanaka, N., Kitanaka, J., Yoshihara, D., Ookawara, T., and Suzuki, K. 2008. Effects of copper metabolism on behavioral functions and brain monoamine contents in Wistar and Wilsons disease model rats. Cell Biology and Toxicology. 24(S1):S64-65.
  • Gabriela, C.E., Mircea, M., Geza, G., and Georgeta, B. 2008. Drinking water: an essential condition for the human existence. Cell Biology and Toxicology. 24(S1):S102.
  • Gao, J., Li, X., Liu, X., and Liu, L. 2008. Assessments of exposure to dietary trace elements in China. Cell Biology and Toxicology. 24(S1):S3-4.
  • Gellein, K., Flaten, T.P., Erikson, K., Aschner, M., and Svversen, T. 2008. Effects of formalin fixation on trace element concentrations in biological tissue. Cell Biology and Toxicology. 24(S1):S101.
  • Gellein, K., Roos, P.M., Evje, L., Vesterberg, O., Flaten, T.P., Nordberg, M., and Syversen, T. 2008. Separation of proteins in cerebrospinal fluid by size exclusion HPLC and determination of trace elements by HR ICP MS. Cell Biology and Toxicology. 24(S1):S106.
  • Franklin, R., Zou, J., and Costello, L. 2008. Zinc regulates NFkappaB and AP1 transcription factors in prostate cancer cells. Cell Biology and Toxicology. 24(S1):S30-31.
  • Freeland Graves, J., and Dai, Z. 2008. International dietary standards for trace elements. Cell Biology and Toxicology. 24(S1):S110-111.
  • Friel, J., Yang, H., Rossel, S., and Tsopmo, A. 2008. Molybdenum content in infant formulas from North America. Cell Biology and Toxicology. 24(S1):S18-19.
  • Frisk, P., Molin, Y., and Ilback, N. G. 2008. Tissue uptake of mercury is changed during the course of a common viral infection in mice. Cell Biology and Toxicology. 24(S1):S51 -52.
  • Fujisawa, C., Kodama, H., Shiga, K., Gu, Y., and Kaga, F. 2008. Identification of ATP7A mutations associated with Menkes disease. Cell Biology and Toxicology. 24(S1):S60.
  • Trif, A., Dumitrescu, E., and Muselin, F. 2008. The consequences of female rats exposure to aluminum sulphate on some sexual hormones. Cell Biology and Toxicology. 24(S1):S44.
  • Trif, A., Muselin, F., and Argherie, D. 2008. The consequences of aluminium exposure on rats genital organs and sexual accessory gland histoarchitecture: three generation experiment. Cell Biology and Toxicology. 24(S1):S41-42.
  • Takahashi, Y., Tsuruta, S., Yasutake, A., and Sawada, M. 2008. Speciation of mercury in the tissues of the rats which received dental amalgam fillings. Cell Biology and Toxicology. 24(S1):S86.
  • Takeda, A., Fuke, S., Sakurada, N., Minami, A., and Oku, N. 2008. Involvement of zinc in synaptic plasticity and neurodegeneration in the hippocampus via crosstalk with calcium. Cell Biology and Toxicology. 24(S1):S74.
  • Tamano, H., Fumika, K., Takeda, A., and Oku, N. 2008. Enhancement of aggressive behavior of young mice induced with social isolation in zinc deficiency. Cell Biology and Toxicology. 24(S1):S75.
  • Thomassen, Y. 2008. Challenges in speciation of workroom air exposures. Cell Biology and Toxicology. 24(S1):S111-112.
  • Thomson, C., and Chisholm, A. 2008. Bioavailability of selenium in Brazil nuts. Cell Biology and Toxicology. 24(S1):S18.
  • Timoshina, D., Tretiakov, A., Kapustinskaya, O., and Burlak, G. 2008. Hygiene and toxicology of Zn and Pb containing ship paints. Cell Biology and Toxicology. 24(S1):S92-93.
  • Trzcinka Ochocka, M., Jakubowski, M., and Janasik, B. 2008. The effects of low level cadmium exposure on bone density. Cell Biology and Toxicology. 24(S1):S76-77.
  • Vala Ragnarsdottir, K., and Hawkins, D.J. 2008. Trace metal abundance soil and grass in Iceland: links with sheep scrapie. Cell Biology and Toxicology. 24(S1):S19.
  • Varnai, V.M., Piasek, M., and Saric, M.M. 2008. Does calcium supplementation during the suckling period affect bone mineral density and bone zinc later in adult rats Cell Biology and Toxicology. 24(S1):S77-78.
  • Volotovski, I., and Slobozanina, E. 2008. The cellular effects induced by Pb2+ and Zn2+ action on human erythrocytes and lymphocytes. Cell Biology and Toxicology. 24(S1):S82.
  • Vrtovec, M., Briski, A., Vidmar, G., and Kocijancic, A. 2008. Is plasma chromium concentration a predictor for favourable effect of chromium supplementation Cell Biology and Toxicology. 24(S1):S38-39.
  • Ward, N., and Marcilla, A. 2008. Boron in the environment and human population of San Juan, Argentina. Cell Biology and Toxicology. 24(S1):S17.
  • Watanabe, A., Shimizu, N., Hemmi, H., and Aoki, T. 2008. Strategy of molecular diagnosis for Wilson disease in Japan. Cell Biology and Toxicology. 24(S1):S63.
  • Wennberg, M., Bergdahl, I., Eliasson, M., Hallmans, G., Stromberg, U., Skerfving, S., Lundh, T., Vessby, B., and Jansson, J. H. 2008. Fish intake, fatty acids, mercury, selenium and risk of myocardial infarction: design of a prospective case control study. Cell Biology and Toxicology. 24(S1):S36-37.
  • Westermarck, T., Plonka Poltorak, E., and Atroshi, F. 2008. Effect of valproic acid treatment on serum clinical and blood hematological values in epileptic subject supplemented with selenium and antioxidant cocktails. Cell Biology and Toxicology. 24(S1):S64.
  • Westermarck, T., Sauka, M., Selga, G., Skesters, A., Abdulla, M., and Atroshi, F. 2008. Effects of cocktail antioxidant supplementation on oxidative stress in aids. Cell Biology and Toxicology. 24(S1):S55-56.
  • Woo, J. M. 2008. Risk analysis of selenium in Korean health functional foods. Cell Biology and Toxicology. 24(S1):S23.
  • Wright, P., Lalor, G., Rattray, V., and Hanson, R. 2008. Health consequences of exposure to diet sourced environmental cadmium in Central Jamaica. Cell Biology and Toxicology. 24(S1):S86-87.
  • Xiao, C., Guoying, Z., Taiyi, J., Lijian, L., and Yihuai, L. 2008. Recovery of bone status after abandoning ingesting cadmium rice for 10 years. Cell Biology and Toxicology. 24(S1):S80.
  • Yokel, R., and Florence, R. 2008. Oral aluminum bioavailability from representative foods shows food provides much more al to systemic circulation, and potential al body burden, than does drinking water. Cell Biology and Toxicology. 24(S1):S16-17.
  • Yokoi, K., Sandstead, H.H., Egger, N.G., Alcock, N.W., Ramanujam, V.M.S., Dayal, H.H., and Penland, J.G. 2008. Dietary origin of simultaneous deficiency of zinc and iron in humans. Cell Biology and Toxicology. 24(S1):S61.
  • Young, A. 2008. Overview of human physiological responses to environmental extremes. Cell Biology and Toxicology. 24(S1):S120-121.
  • Zachara, B., Gromadzinska, J., Zbrog, Z., Swiech, R., Jablonska, E., Twardowska, E., and Wasowicz, W. 2008. The effect of selenium supplementation to hemodialysis patients on plasma glutathione peroxidase (GSH Px) activity and GSH Px protein level. Cell Biology and Toxicology. 24(S1):S57-58.
  • Zamana, S.P., Kutrovsky, V.N., and Fedorowskiy, T.G. 2008. The element composition of cows milk of Moscow region. Cell Biology and Toxicology. 24(S1):S13.
  • Zitkevicius, V., Savickiene, N., Smalinskiene, A., Lesauskaite, V., Ryselis, S., Abdrakhmanov, O., Sadauskiene, I., Ivanov, L., and Savickas, A. 2008. Comparison of effects of Echinacea purpurea and Eleutherococcus senticosus (rupr. et maxim. ex maxim) extracts on the accumulation of cadmium in different organs Mitotic activity of liver cells. Cell Biology and Toxicology. 24(S1):S83-84.
  • Aaseth, J., Andersen, O., Flaten, T.P., and Gellein, K. 2008. Iron and copper toxicity in hereditary diseases. Cell Biology and Toxicology. 24(S1):S60-61.
  • Abdulah, R., Kobayashi, K., Faried, A., Katsuya, Y., Otani, T., Ito, K., Suzuki, K., Murakami, M., Kuwano, H., and Koyama, H. 2008. Anticancer activity of selenium enriched broccoli sprouts in human prostate cancer cell lines. Cell Biology and Toxicology. 24(S1):S32-33.
  • Ho, E. 2008. Effect of zinc on DNA integrity and cancer risk. Cell Biology and Toxicology. 24(S1):S127.
  • Abdulla, M., Gamon, S., Chazot, G., Bost, M., and Shukla, S. 2008. Trace element nutrition: a neglected health issue in developing countries. Cell Biology and Toxicology. 24(S1):S113-114.
  • Aghajan, M., Kalantari, S., and Sobhan, A. 2008. Selenium as an antioxidant in the thyroid gland. Cell Biology and Toxicology. 24(S1):S87.
  • Akesson, A. 2008. Kidney and bone effects of low dose cadmium exposure in Sweden. Cell Biology and Toxicology. 24(S1):S119 20.
  • Alanyali, F., Ozata, A., and Basoglan, O. 2008. Investigation of cytotoxic effects of thallium acetate and ellagic acid on NIH 3T3 cell line. Cell Biology and Toxicology. 24(S1):S90 1.
  • Allen, L. 2008. Future dietary standards for trace elements. Cell Biology and Toxicology. 24(S1):S111.
  • Althaus, J., Althaus, C., Bisgaier, C., Kanzer, S., and Brewer, G. 2008. Tetrathiomolybdate for Wilsons disease inhibits copper dependent lipid peroxidation. Cell Biology and Toxicology. 24(S1):S95.
  • Althaus, J., Lee, K. H., Bisgaier, C., and Kanzer, S. 2008. Novel device for direct measurement of non ceruloplasmin copper in Wilsons disease. Cell Biology and Toxicology. 24(S1):S105 6.
  • Anderson, R.A., Bryden, N., Polansky, M., Hininger Favier, I., Benaraba, R., and Roussel, A. 2008. Safety, absorption, and antioxidant effects of chromium histidine. Cell Biology and Toxicology. 24(S1):S41.
  • Anke, M. 2008. Iodine in the food chain of animala and man: intake, balance and requirement. Cell Biology and Toxicology. 24(S1):S115 6.
  • Araujo Jorge, T., De Souza, A.P., Melo Medeiros, M., and Rivera, M. T. 2008. Micronutrient treatment improves cardiac damage in mice infected with trypanosoma cruzi. Cell Biology and Toxicology. 24(S1):S37.
  • Araya, M., Nunez, H., Arredondo, M., Pizarro, F., Mendez, M., and Olivares, M. 2008. Chronic copper toxicity in a non human primate model: preliminary results. Cell Biology and Toxicology. 24(S1):S61-62.
  • Arnay De La Rosa, M., Gonzalez Reimers, E., Gamez Mendoza, A., and Galindo Martin, L. 2008. The Ba Sr ratio, carious lesions, and dental calculus among the population buried in La Concepcion (tenerife, canary islands). Cell Biology and Toxicology. 24(S1):S81.
  • Aschner, M., Fitsanakis, V., Zhang, N., Anderson, K., Gore, J., and Avison, M. 2008. Changes in dietary iron levels affect brain manganese accumulation and distrubution. Cell Biology and Toxicology. 24(S1):S122 3.
  • Baranova, O., Notova, S., Skalny, A., and Chadova, L. 2008. Mineral status of energy enterprise workers: results of correction. Cell Biology and Toxicology. 24(S1):S14 5.
  • Barregard, L. 2008. Neurological and renal effects of low dose exposure to elemental mercury exposure from amalgam in children. Cell Biology and Toxicology. 24(S1):S119.
  • Basoglan, O., Susuz, F., and Canturk, Z. 2008. Investigation of cytotoxic effects of thallium acetate and ellagic acid on C6 cell line. Cell Biology and Toxicology. 24(S1):S26.
  • Baxter, D., and Rodushkin, I. 2008. Elemental analysis of biological materials state of the art. Cell Biology and Toxicology. 24(S1):S107 8.
  • Baxter, D., Rodushkin, I., and Berglund, I. 2008. Methyl mercury in biological fluids by isotope dilution. Cell Biology and Toxicology. 24(S1):S104.
  • Benzo, Z., Papale, J., Quintal, M., Berne, Y., Torres, M., Gimenez, E., Castro, M., and Briceno, Z. 2008. Anaemia, iron deficiency, and parasitism in children from a rural community of Venezuela. Cell Biology and Toxicology. 24(S1):S53.
  • Bertinato, J., Swist, E., Iskandar, M., and LAbbe, M. 2008. Maintaining copper balance: roles of copper transporters and chaperones. Cell Biology and Toxicology. 24(S1):S127.
  • Bikashvili, T., Shukakidze, A., Chkhartishvili, N., and Lazrishvil, I. 2008. Effect of subchronic manganese intoxication on brain morphology and manganese level in rat pups. Cell Biology and Toxicology. 24(S1):S69.
  • Bolshoy, D., Pykhteeva, E., Shafran, L., and Tretiakova, E. 2008. Small doses of mercury exposure: what does it mean Cell Biology and Toxicology. 24(S1):S92.
  • Bordallo, H., Bartz, T., Alber, D., and Kyriakopoulos, A. 2008. Trace elements in the digestive system of the rat. Cell Biology and Toxicology. 24(S1):S4.
  • Bost, M., Maffre, V., Vaillant, F., Bui Xuan, B., Tabib, A., Descotes, J., Chazot, G., and Timou, Q. 2008. Effect of selenium supplementation on heart lesions produced by neuroleptics. Cell Biology and Toxicology. 24(S1):S37.
  • Bost, M., Piguet Lacroix, G., Pelosse, M., Gincul, R., Broussolle, E., Xie Brustolin, J., Dumortier, J., and Lachaux, A. 2008. Mutation analysis in French Wilson disease patients: Identification of prevalent substitution and eleven novel mutations in the atp7b gene. Cell Biology and Toxicology. 24(S1):S59-60.
  • Brenneisen, P. 2008. Oxidative stress in tumor progression: intervention by selenium. Cell Biology and Toxicology. 24(S1):S126.
  • Brewer, G. 2008. Overview of the role of copper in neurologic and neurodegenerative diseases and potential treatment with tetrathiomolybdate. Cell Biology and Toxicology. 24(S1):S116.
  • Buentzel, J., Glatzel, M., Bruns, F., Kisters, K., Micke, O., and Muecke, R. 2008. Selenium supplementation in head and neck surgery. Cell Biology and Toxicology. 24(S1):S28-29.
  • Darago, A., Taczalski, J., Sapota, A., and Kilanowicz, A. 2008. Selected trace elements and cadmium concentrations in malignant, hypertrophic, and normal prostatic tissues. Cell Biology and Toxicology. 24(S1):S22.
  • Endo, G., Habib, A., Hata, A., Nakajima, Y., Matsuda, M., Ogawa, M., and Endo, Y. 2008. Speciation analysis by HPLC ICP MS of arsenic in urine of individuals drinking polluted water in bangladesh. Cell Biology and Toxicology. 24(S1):S91.
  • Endo, Y. 2008. Toxic methylation of dimethyltin to trimethyltin in human. Cell Biology and Toxicology. 24(S1):S84.
  • Eby, G. 2008. Elimination of arthritis pain and inflammation for over 2 years with a single 90 min, topical 14 percent gallium nitrate treatment: case reports and review of actions of gallium(III). Cell Biology and Toxicology. 24(S1):S79.
  • Ermakov, V. 2008. Se deficiency and manifestation of Urov disease in East Siberia. Cell Biology and Toxicology. 24(S1):S80-81.
  • Ermakov, V., and Soboleeva, A. 2008. Molybdenum in the environment in connection with biological effects. Cell Biology and Toxicology. 24(S1):S3.
  • Ermidou Pollet, S., Gabrashanska, M., Koinarski, V., Denev, S., Pollet, S., and Anisimova, M. 2008. Influence of selenium and Eimeria tenella infection on antioxidant status in chicks: status and resistance against infections. Cell Biology and Toxicology. 24(S1):S55.
  • Ermidou Pollet, S., and Pollet, S. 2008. The relevance of trace element nutrition in human health. Cell Biology and Toxicology. 24(S1):S110.
  • Esaki, N., Mihara, H., and Kurokawa, S. 2008. Mechanism of selenocysteine lyase: strict discrimination between selenium and sulfur. Cell Biology and Toxicology. 24(S1):S62.
  • Evje, L., Aspnes, M.A., and Svversen, T. 2008. Trace elements in nutritional supplements. Cell Biology and Toxicology. 24(S1):S9.
  • Faltmarsch, R., Astrom, M., and Vuori, K.M. 2008. Environmental risks of potentially toxic metals mobilised from acid sulphate soils in Finland: a literature review. Cell Biology and Toxicology. 24(S1):S8-9.
  • Ferin, R., Napoleao, P., Gomes, C., Castro, A.R., Lopes, P.A., Martins, D., Santos, M.C., Baptista, J., Viegas Crespo, A.M., Pinheiro, T., and Pavao, M.L. 2008. Blood antioxidant markers and elemental levels in Azorean patients with coronary artery disease: a preliminary study. Cell Biology and Toxicology. 24(S1):S33-34.
  • Filiou, D., Mila, S., Gorezis, P., Koutras, V., Evangelou, A., and Kalfakakou, V. 2008. Nutritional value of processed vs. traditional snacks, consumed by children, in relation to their Zn and Cu content. Cell Biology and Toxicology. 24(S1):S49.
  • Flaten, T.P., Andersen, L.H., Holsen, A.M.H., Ottemo, V.G., Pedersen, H.C., Steinnes, E., Lierhagen, S., and Jenssen, B.M. 2008. A nation wide survey of trace elements in lynx, wolverines, wolves, and brown bears in Norway. Cell Biology and Toxicology. 24(S1):S6-7.
  • Fowler, B., Conner, E., Yamauchi, H., and Wang, G. 2008. Proteomic and metabolomic biomarkers for assessing low dose toxic trace element interactions: an overview. Cell Biology and Toxicology. 24(S1):S118-119.
  • Gellein, K., Skogholt, J., Aaseth, J., Thoresen, G.B., Lierhagen, S., Svversen, T., Steinnes, E., and Flaten, T.P. 2008. Trace elements in cerebrospinal fluid and blood from patients with a rare progressive central and peripheral demyelinating disease. Cell Biology and Toxicology. 24(S1):S65-66.
  • Gellein, K., Svversen, T., Steinnes, E., Nilsen, T.I.L., Lierhagen, S., Dahl, O.P., Mitrovic, S., Duraj, D., and Flaten, T.P. 2008. Trace elements in serum from patients with Parkinsons disease a prospective case control study. Cell Biology and Toxicology. 24(S1):S65.
  • Gharib, A. 2008. Analytical data on Iranian typical diets and its bioavailability aspect by trace elemental study in daily diets. Cell Biology and Toxicology. 24(S1):S20.
  • Golian, J., Zajac, P., Toman, R., and Siska, B. 2008. Contamination of selected food by heavy metals. Cell Biology and Toxicology. 24(S1):S5-6.
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