Source: CORNELL UNIVERSITY submitted to
PH.D TRAINING PROGRAM IN FARM-TO-TABLE FOOD SAFETY AND BIOSECURITY
Sponsoring Institution
National Institute of Food and Agriculture
Project Status
TERMINATED
Funding Source
Reporting Frequency
Annual
Accession No.
0203764
Grant No.
2005-38420-15776
Project No.
NYC-143750
Proposal No.
2005-02309
Multistate No.
(N/A)
Program Code
KK
Project Start Date
Sep 1, 2005
Project End Date
Aug 31, 2010
Grant Year
2005
Project Director
Boor, K.
Recipient Organization
CORNELL UNIVERSITY
(N/A)
ITHACA,NY 14853
Performing Department
FOOD SCIENCE
Non Technical Summary
Our ability to provide comprehensive protection of the US and global food supply will relay on the availability of individuals who understand the vulnerabilities of the food suppy from food's point of production to its point of consumption (farm-to-table protection). To that end, Ph.D.-level scientists with a comprehensive understanding of both pre- and post-harvest food safety issues are needed to assure a safe food supply for the US, as well as a national food industry that remains competitive in global trade. The supply of well-trained food safety professionals with an integrated farm-to-table understanding of the US food system is currently limited. This project will develop a comprehensive Ph.D. training program in farm-to-table food safety and biosecurity to ensure that individuals capable of addressing complex food safety issues are available.
Animal Health Component
(N/A)
Research Effort Categories
Basic
(N/A)
Applied
100%
Developmental
(N/A)
Classification

Knowledge Area (KA)Subject of Investigation (SOI)Field of Science (FOS)Percent
90360993020100%
Goals / Objectives
Farm-to-table food safety and biosecurity represent increasingly critical areas of scientific national need. The supply of well-trained food safety professionals with an integrated farm-to-table understanding of the US food system is limited. To fill this gap, we propose to develop a comprehensive Ph.D. training program in farm-to-table food safety and biosecurity. The specific objective of this program is to recruit, train, and mentor a Ph.D. student for a career in farm-to-table food safety and biosecurity.
Project Methods
We will provide a comprehensive Ph.D. training program in farm-to-table food safety and biosecurity. We will focus our recruitment efforts on students from traditionally underrepresented minorities and first generation college students. The basic components of our program are: (1) a core farm-to-table food safety curriculum to provide fundamental knowledge, supplemented with appropriate electives; (2) multidisciplinary dissertation research projects; (3) journal clubs and seminars in farm-to-table food safety; (4) close interactions with advisors' interdisciplinary contacts and their research groups; (5) regular participation in professional and scientific meetings; (6) opportunities for internships in industry and regulatory agencies, and (7) a comprehensive mentoring and advising program. Unique aspects of this training program include (i) a truly multidisciplinary training program that bridges veterinary medicine and food science to include molecular microbiology, epidemiology, risk assessment, microbial pathogenesis and food safety economics, and (ii) internship opportunities at the FDA Center for Food Safety and Applied Nutrition, the FDA Center for Veterinary Medicine, the Centers for Disease Control, as well as other federal and state agencies and food industry partners. The structure fo the program will ensure that PhD students are prepared for a career in food safety and biosecurity.

Progress 09/01/05 to 08/31/10

Outputs
The student supported in this training grant has completed his Ph.D. training in food safety and biodefense. He has published one additional manuscript, and his work has been published in 2 additional abstracts for the 2010 American Society for Microbiology Annual Meeting, where he presented a poster. FINAL SIGNIFICANT OUTPUTS AND DISSIMINATION ACTIVITIES: Throughout the term of this grant, the supported student has had 4 peer-reviewed manuscripts published or accepted for publication, and he is in the process of completing two other manuscripts describing his Ph.D. research. Throughout the course of this grant, he has published 6 abstracts describing his work. Outcomes of his research were presented at the 2007, 2009, and 2010 American Society for Microbiology meetings and the 2008 and 2009 International Association for Food Protection meetings. He has given oral presentations on the outcomes of his research at the 2007 American Society for Microbiology and 2008 International Association for Food Protection meetings. PRODUCTS: One additional manuscript by the student supported by this grant has been accepted for publication. In total, 4 manuscripts describing his research results have been accepted or published throughout the course of this grant. OUTCOMES: The student supported by this grant has successfully completed all of the requirements for his Ph.D. and, after considering several opportunities, has accepted a postdoctoral associate position at Cornell University. His postdoctoral research will focus on improving the microbiological quality and safety of fluid milk. DISSEMINATION ACTIVITIES: The research activities of the supported student were presented in two abstracts at the 2010 American Society for Microbiology Annual Meeting, where he presented a poster. The findings of his Ph.D. research project were presented in a public seminar at Cornell University. FUTURE INITIATIVES: This termination report summarizes the lifetime of the project and changes the project status in CRIS to terminated. No future initiatives reported.

Impacts
Through the support of this grant, we have prepared one new Ph.D. for a career in food protection and defense.

Publications

  • Ivy, R.A., Chan, Y.C., Bowen, B.M., Boor, K.J.B., and Wiedmann, M. Growth temperature-dependent contributions of response regulators, {sigma}B, PrfA, and motility factors to Listeria monocytogenes invasion of Caco-2 cells. Foodborne Pathogens and Disease. FPD-2010-0563; Accepted 2010.


Progress 09/01/08 to 08/31/09

Outputs
The PhD student supported on this training grant has scheduled his final exam for summer 2010, hence is nearing completion of his program. He has one additional manuscript submitted for publication and had an abstract published from the 2009 American Society for Microbiology Annual meeting, where he presented a poster. PRODUCTS: The student supported by this training grant will have authored 4 peer-reviewed manuscripts at completion of his PhD. He has published 5 abstracts describing his work. His research was presented at the American Society for Microbiology in 2007 and 2009 and at the International Association for Food Protection in 2007 and 2008. OUTCOMES: The student supported by this training grant has multiple offers for post-doctoral studies, all in the area of food protection and defense. DISSEMINATION ACTIVITIES: Research outcomes completed by the student supported by this training grant were presented at the American Society for Microbiology annual meetings in 2007 and 2009 and at the International Association for Food Protection annual meetings in 2007 and 2008. In addition, Dr. Carmen Moraru attended the second Joint Meeting for the National Needs Graduate Fellowship Grants and Higher Education Multicultural Scholars Program (MSP) Project Directors and Beneficiaries that was held in Washington, DC, on Tuesday/Wednesday, October 20-21, 2009. She reported on the activities and outcomes of this training grant. FUTURE INITIATIVES: I will continue to seek funding opportunities to support new graduate students in the area of food protection and defense.

Impacts
At the end of this training grant, we will have prepared one new PhD for a career in food protection and defense.

Publications

  • No publications reported this period


Progress 09/01/07 to 08/31/08

Outputs
Microbial food safety issues generate attention that affects commerce around the globe. Association of a commodity or specific product with a food safety problem, whether real or perceived, can negatively affect export opportunities for US food industries. In the U.S., public concern at least partially reflects extensive media coverage of food safety issues, including foodborne disease outbreaks and product recalls due to microbial contamination. In very recent years, the need to develop integrated farm-to-table approaches for ensuring the safety and biosecurity of agricultural products has become apparent. As a consequence of the increasingly recognized need for effective strategies to prevent accidental or intentional food-related illnesses, employment opportunities in industry, in academia, and in state and federal agencies are currently expanding for those with training in food safety. The program proposed in this application was designed to prepare new scientists with appropriate training and experience to address factors affecting the safety of foods grown, harvested, distributed, and consumed in the context of highly complex food production and processing systems. This current project is supporting one graduate student for three years. The student initiated his graduate studies in September 2006. PRODUCTS: An outstanding student is at a mid-point in his training program and he has already contributed to 3 peer-reviewed, published manuscripts. OUTCOMES: The student supported by this program is recognized as a future leader in the food safety and biosecurity area. DISSEMINATION ACTIVITIES: Through recruitment and retention activities associated with the program, associated faculty have raised awareness of food safety training opportunities at Cornell University. Further, the student supported by this training grant presented a poster on his research at the American Society for Microbiology annual meeting in Boston, MA. FUTURE INITIATIVES: National Needs Fellowship research and training results will be reported through at least one oral or poster presentation at an appropriate national or international meeting (e.g., the annual meeting of the American Society for Microbiology or the Institute of Food Technologists) in 2009.

Impacts
Strong, collaborative food safety research efforts established by program faculty provide a framework for a unique mentoring environment that will produce Ph.D. scholars capable of leadership in the field of food safety and biosecurity.

Publications

  • Orsi, R. H., M. Borowsky, P. Lauer, S. K Young, C. Nusbaum, J. E. Galagan, B. W. Birren, R. A. Ivy, Q. Sun, L.M. Graves, B. Swaminathan, and M. Wiedmann. 2008. Short-term genome evolution of Listeria monocytogenes in a non-controlled environment. BMC Genomics Nov 13; 9(1):539. [Epub ahead of print]
  • Nightingale, K. K., R. A. Ivy, A. J. Ho, E. D. Fortes, B. L. Njaa, R. M. Peters, and M. Wiedmann. 2008. inlA premature stop codons are common among Listeria monocytogenes isolated from foods and yield virulence-attenuated strains that confer protection against infection by fully virulent L. monocytogenes strains. Appl. Environ. Micro. 74:6570 6583.


Progress 09/01/06 to 08/31/07

Outputs
Microbial food safety issues generate attention that affects commerce around the globe. Association of a commodity or specific product with a food safety problem, whether real or perceived, can negatively affect export opportunities for US food industries. In the U.S., public concern at least partially reflects extensive media coverage of food safety issues, including foodborne disease outbreaks and product recalls due to microbial contamination. In very recent years, the need to develop integrated farm-to-table approaches for ensuring the safety and biosecurity of agricultural products has become apparent. As a consequence of the increasingly recognized need for effective strategies to prevent accidental or intentional food-related illnesses, employment opportunities in industry, in academia, and in state and federal agencies are currently expanding for those with training in food safety. The program proposed in this application was designed to prepare new scientists with appropriate training and experience to address factors affecting the safety of foods grown, harvested, distributed, and consumed in the context of highly complex food production and processing systems. This current project is supporting one graduate student for three years. The student initiated his graduate studies in September 2006. PRODUCTS: An outstanding student has successfully initiated his training program and he has already contributed to a peer-reviewed, published manuscript. OUTCOMES: The student supported by this program is recognized as a future leader in the food safety and biosecurity area. DISSEMINATION ACTIVITIES: Through recruitment activities associated with the program, associated faculty have raised awareness of food safety training opportunities at Cornell University. Further, co-PI Martin Wiedmann presented a poster and presentation on the training grant at the 2007 Annual Conference on the National Needs and Multicultural Scholars program in Washington DC on Oct. 16 and 17. Further, the student supported by this training grant presented a poster on his research at the American Society for Microbiology annual meeting in Toronto, Canada. FUTURE INITIATIVES: National Needs Fellowship research and training results will be reported through at least one oral or poster presentation at an appropriate national or international meeting (e.g., the annual meeting of the Institute of Food Technologists) in 2008.

Impacts
Strong, collaborative food safety research efforts established by program faculty provide a framework for a unique mentoring environment that will produce Ph.D. scholars capable of leadership in the field of food safety and biosecurity.

Publications

  • Nightingale, K., S. R. Milillo, R. A. Ivy, A. J. Ho, H. F. Oliver, and M. Wiedmann. 2007. Listeria monocytogenes F2365 carries several authentic mutations potentially leading to truncated gene products, including InlB, and demonstrates atypical phenotypic characteristics. J. Food Prot. 70: 482-488.


Progress 09/01/05 to 09/01/06

Outputs
Microbial food safety issues generate attention that affects commerce around the globe. Association of a commodity or specific product with a food safety problem, whether real or perceived, can negatively affect export opportunities for US food industries. In the U.S., public concern at least partially reflects extensive media coverage of food safety issues, including foodborne disease outbreaks and product recalls due to microbial contamination. In very recent years, the need to develop integrated farm-to-table approaches for ensuring the safety and biosecurity of agricultural products has become apparent. As a consequence of the increasingly recognized need for effective strategies to prevent accidental or intentional food-related illnesses, employment opportunities in industry, in academia, and in state and federal agencies are currently expanding for those with training in food safety. The program proposed in this application was designed to prepare new scientists with appropriate training and experience to address factors affecting the safety of foods grown, harvested, distributed, and consumed in the context of highly complex food production and processing systems. This current project will support one graduate student for three years. Following nearly a year of aggressive recruitment strategies including advertising, personal recruitment (e.g., faculty associated with the program attended multiple national and international food safety meetings and interacted with numerous prospective students and faculty) screening of applications and interviews of numerous highly qualified candidates, an outstanding student has been selected for support by this program. We recruited him into the program and he initiated his graduate studies in September 2006, hence, he is not listed as supported during the reporting period. The student has an MS in food safety from the University of Arkansas and will now pursue a multi-disciplinary food safety program here at Cornell. He was such a high quality candidate that he is currently supported by a 1 year fellowship from another program, therefore, his support from the National Needs program will initiate at the end of the 2006-07 academic year. PRODUCTS: An outstanding student has been successfully recruited into the training program. OUTCOMES: An outstanding student has initiated his Ph.D. work in this multidisciplinary training program. DISSEMINATION ACTIVITIES: Through recruitment activities associated with the program, associated faculty have raised awareness of food safety training opportunities at Cornell University. FUTURE INITIATIVES: National Needs Fellowship research and training results will be reported through at least one oral or poster presentation at an appropriate national or international meeting (e.g., the annual meeting of the Institute of Food Technologists) in 2007.

Impacts
Strong, collaborative food safety research efforts established by program faculty provide a framework for a unique mentoring environment that will produce Ph.D. scholars capable of leadership in the field of food safety and biosecurity.

Publications

  • No publications reported this period