Progress 10/01/03 to 09/30/08
Outputs
OUTPUTS: Consumption of fruits and vegetables containing high levels of dietary phytochemicals has been associated with a reduced incidence of human cancers. This CRIS project is focused on flavonoids in vegetables and lignans in wheat bran for cancer prevention studies. In the past year, we have conducted and published three articles related to phytochemical contents in organically grown vegetables and lignans in wheat products. We shared these research information to communities by providing three seminars, presenting a poster in national conference, and training 4 undergraduate students and 2 graduate students. PARTICIPANTS: Wang W (P.I.) Carey EE (collaborator) Ayella A (graduate student) Zhao X (graduate student) Kacey H. Provenzano (undergraduate student) Xiaoyu Su (undergraduate student) Genna Gehrt (undergraduate student) Rita Perez (undergraduate student) TARGET AUDIENCES: Nothing significant to report during this reporting period. PROJECT MODIFICATIONS: Nothing significant to report during this reporting period.
Impacts
This CRIS project supported a study to define the role of phytochemicals in cancer prevention and to develop new value-added wheat products for health-promoting benefits. The molecular mechanism by which certain phytochemicals may protect against cancer in organically grown vegetables and the new wheat line(s) via over-expressing lignan biosynthesis enzyme may provide a novel marketing opportunity for wheat agriculture in Kansas.
Publications
- Wang W, Ayella A, Jiang Y, Ouyang P, Qu H. Wheat lignans: promising cancer preventive agents. In: Wheat Antioxidants (Ed. Liu, L.). John Wiley & Sons, Ltd., 2008; p 264-272.
- Zhao X, Nechols JR, Williams KA, Wang W, Carey EE. Comparison of phenolics in organically and conventionally grown Pac Choi (Brassica rapa L. Chinensis group). Journal of the Science of Food and Agriculture 2009; in press.
- Ayella AK, Wang W. Lignan Biosynthesis Enhancement in Transgenic Wheat. In: Transgenic Plants: New Research (ed. Columbus F). Nova Science Publishers, Inc., Hauppauge, NY, 2009; in press.
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Progress 01/01/07 to 12/31/07
Outputs
OUTPUTS: Consumption of fruits and vegetables containing high levels of dietary phytochemicals has been associated with a reduced incidence of human cancers. This CRIS project is focused on flavonoids in vegetables and lignans in wheat bran for cancer prevention studies. In the past year, we have conducted and published one more article related to phytochemical contents in organically grown vegetables. In addition, we published two more articles regarding lignans in wheat products and genetic transformation of wheat for enhanced lignan contents.
PARTICIPANTS: Janice E. Young, Allan K. Ayella, Yu Jiang, Ping Ouyang, Honyan Qu, Weiqun Wang
Impacts
This CRIS project supported a study to define the role of phytochemicals in cancer prevention and to develop new value-added wheat products for health- promoting benefits. The molecular mechanism by which certain phytochemicals may protect against cancer in organically grown vegetables and the new wheat line(s) via over-expressing lignan biosynthesis enzyme may provide a novel marketing opportunity for wheat agriculture in Kansas.
Publications
- Zhao X, Young JE, Wang W, Iwamoto T, Carey EE. Influences of organic fertilization, high tunnel environment, and postharvest storage on phenolic compounds in lettuce. HortScience 2007; 42(1):71-76.
- Ayella AK, Trick HN, Wang W. Enhanced lignan biosynthesis by over- expressing pinoresinol lariciresinol reductase in transgenic wheat. Molecular Nutrition and Food Research 2007; 51(12):1518-1526.
- Wang W, Ayella A, Jiang Y, Ouyang P, Qu H. Wheat lignans: promising cancer preventive agents. In: Wheat Antioxidants (Ed. Liu, L.). John Wiley & Sons, Ltd., 2008; p 264-272.
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Progress 01/01/06 to 12/31/06
Outputs
Consumption of fruits and vegetables containing high levels of dietary phytochemicals has been associated with a reduced incidence of human cancers. This CRIS project is proposed to define cancer preventive agents in vegetables and wheat bran in colorectal cancer models. In the past year, we have conducted and published two articles related to phytochemical contents in organically grown vegetables. In addition, we submitted an invited book chapter, describing lignan compounds in wheat products. Furthermore, we are conducting two more on-going studies. One is related to conjugated lignan from wheat bran in colorectal cancer prevention and another one is to enhance lignan contents in wheat by transgenic method.
Impacts
This CRIS project supported a study to define the role of phytochemicals in cancer prevention and to develop new value-added plant foods for health-promoting benefits. The molecular mechanism by which certain phytochemicals may protect against colorectal cancer and the new wheat line(s) via over-expressing lignan biosynthesis enzyme may provide a novel marketing opportunity for wheat agriculture in Kansas.
Publications
- Wang W, Ayella A, Jiang Y, Ouyang P, Qu H. 2006 Wheat lignans: promising cancer preventive agents. In: Wheat Antioxidants. Wiley Inc., Accepted; in press.
- Zhao X, Carey EE, Wang W, Rajashekar CB. 2006, Does organic production enhance phytochemical content of vegetables and fruits? current knowledge and prospects for research. HortTechnology ; 16:449-456.
- Zhao X, Young JE, Wang W, Iwamoto T, Carey EE. 2006, Influences of organic fertilization, high tunnel environment, and postharvest storage on phenolic compounds in lettuce. HortScience Accepted: in press.
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Progress 01/01/05 to 12/31/05
Outputs
Consumption of fruits and vegetables containing high levels of dietary phytochemicals has been associated with a reduced incidence of human cancer. This CRIS project is proposed to define cancer preventive agents in vegetables and wheat bran. In the past year, we have published two articles. One reported a HPLC method to measure nine prominent phytochemicals in leafy green vegetables (e.g. lettuce, spinach and other greens) grown organically and conventionally, respectively. Another one reported a relationship of phytochemical lignans in wheat bran with colorectal cancer prevention. To enhance lignan contents in wheat, we developed new transgenic wheat lines by over-expressing lignan biosynthesis enzyme. The overall progress of this study has resulted in two papers and five presentations as listed as follows.
Impacts
This CRIS project supported a study to define the role of phytochemicals in cancer prevention and to develop new value-added plant foods for health-promoting benefits. The new wheat line(s) with over-expressed lignan biosynthesis enzyme generated from this study may provide a novel marketing opportunity for wheat agriculture.
Publications
- Qu H, Madl RL, Takemoto DJ, Baybutt R, Wang W. Phytochemical lignans associated with the cancer prevention by wheat bran. Journal of Nutrition 2005; 135:598-602.
- Young JE, Zhao X, Carey T, Welti R, Yang SS, Wang W. Phytochemical phenolics in organic vegetables. Molecular Nutrition and Food Research 2005; in press
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Progress 01/01/04 to 12/31/04
Outputs
Consumption of fruits and vegetables containing high levels of dietary phytochemicals has been associated with a reduced incidence of human cancer. This CRIS project is proposed to define cancer preventive agents in vegetables and wheat bran. In the past year, we have established a HPLC method and measured nine prominent phytochemicals in leafy green vegetables (e.g. lettuce, spinach and other greens) grown organically and conventionally, respectively. We also measured phytochemical lignans in certain wheat lines. The potential anticancer mechanisms of lignans were further assessed by using an in vitro cell culture system. The overall progress of this study has resulted in two papers, five presentations, and two graduate student research theses as listed as follows.
Impacts
This project aims at defining the role of phytochemicals in cancer prevention, by which the new value-added plant foods may be developed for health-promoting benefits.
Publications
- Hongyan Qu, Ronald L. Madl, Dolores J. Takemoto, Richard C. Baybutt, Weiqun Wang. 2005. Phytochemical Lignans Associated with Cancer Prevention by Wheat Bran: Anti-cancer Characteristics in Colon Cancer SW480 Cells. Journal of Nutrition, In press.
- Janice Young, Weiqun Wang. 2004. Phytochemical Farming: A New Age in Food, Nutrition, and Agriculture. AgroFood Industry Hi-Tech,15:38-39.
- Hongyan Qu. 2004. Phytochemical Lignans May Be Associated with the Capacity of Cancer Prevention by Wheat Bran. Master's Thesis, Kansas State University.
- Janice Young. 2004. Quantitative Analysis of Phenolic Agents in Organic and Conventional Vegetables. Master's Thesis, Kansas State University.
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