Source: UNIVERSITY OF MINNESOTA submitted to NRP
RESEARCH TRAINING OF VETERINARY STUDENTS IN MICROBIAL AND ANIMAL HEALTH GENOMICS
Sponsoring Institution
National Institute of Food and Agriculture
Project Status
COMPLETE
Funding Source
Reporting Frequency
Annual
Accession No.
0196592
Grant No.
2003-38411-13478
Cumulative Award Amt.
$100,000.00
Proposal No.
2003-03875
Multistate No.
(N/A)
Project Start Date
Sep 1, 2003
Project End Date
Aug 31, 2006
Grant Year
2003
Program Code
[ER.V4]- (N/A)
Recipient Organization
UNIVERSITY OF MINNESOTA
200 OAK ST SE
MINNEAPOLIS,MN 55455-2009
Performing Department
REGENTS OF THE UNIVERSITY
Non Technical Summary
University of Minnesota College of Veterinary Medicine Department of Veterinary Pathobiology The purpose of the proposed training program is to provide the opportunity for research training of veterinary students in microbial and animal health genomics to increase their awareness and to develop an interest in using genomic approaches to address critical issues facing veterinary medicine and public health safety. Specifically, our long-term goal is to increase the number of veterinarians pursuing graduate education or postdoctoral genomics training.
Animal Health Component
100%
Research Effort Categories
Basic
(N/A)
Applied
100%
Developmental
(N/A)
Classification

Knowledge Area (KA)Subject of Investigation (SOI)Field of Science (FOS)Percent
90360993020100%
Goals / Objectives
University of Minnesota College of Veterinary Medicine Department of Veterinary Pathobiology The purpose of the proposed training program is to provide the opportunity for research training of veterinary students in microbial and animal health genomics to increase their awareness and to develop an interest in using genomic approaches to address critical issues facing veterinary medicine and public health safety. Specifically, our long-term goal is to increase the number of veterinarians pursuing graduate education or postdoctoral genomics training. This would begin to address the need for increasing the number of individuals trained in veterinary medicine to participate in basic research opportunities of interest to the USDA. With a long-term goal of increasing the training and interest of veterinarians in basic research activities related to the mission of the USDA, the measurable outcomes of this training program include: i) increased participation by veterinary students in research laboratories. ii) increased participation in the combined DVM/Ph.D or DVM/MPH programs offered at the University of Minnesota. iii) increased number of DVM graduates applying to graduate or postdoctoral training programs iv) increased number of DVM graduates applying for funding from the USDA or NIH physician training programs v) increased number of publications including veterinarians or veterinary students
Project Methods
Veterinary students interested in participating in the training program will be provided with a list of faculty research mentors and a description of research opportunities available. Students will be encouraged to identify and meet directly with faculty members to develop short grant applications describing a research project and the reasons for their interest in the program, how they will benefit from the experience, and their future plans. Prior to entering of the research laboratories, all students will be provided safety training as is required for all laboratory personnel within the CVM, AHC, and COAFES. In addition, depending on the research project, students will be required to complete radiation safety training, and animal handling protocols prior to starting the research project. Laboratory research will be conducted under the supervision of faculty mentor. It is expected that students will be directly responsible for the progress of their research projects and will interact daily with graduate students, postdoctoral fellows and research technicians within the mentor's laboratory and with other researchers within the university. To provide students with an opportunity to improve their communication and presentation skills, the training program will run a seminar series during the summer months. Students will be required to present three times during each year of participation. The first seminar will be to present the justification and outline of their research project. The second seminar will be a progress update on their research project, including problems encountered and attempted solutions. These first two seminars will be restricted to only those students and faculty mentors participating in the training program. This is to ensure a non-threatening and friendly learning environment for the students as they begin to learn the difficult and highly evaluative process of presenting research date. The third seminar will occur at the end of the summer and will require students to present their research progress in the Molecular Veterinary Biology Graduate Program Student Research Series. In addition to the writing of a small research grant under the supervision of their faculty member as part of the application to the program, students will be required to present a poster at the annual CVM Research Recognition Day.

Progress 10/01/04 to 09/30/05

Outputs
A total of fifteen students were selected as a result of a competitive process based on their research project proposals. Student proposals were reviewed and final selections were made by two faculty advisory committees. All students have been participating in summer research projects in separate labs or field work studies. Also included in the experience have been a series of seminars and a field trip, with sessions on ethics relating to animal use and clinical and applied research, a panel presentation on alternate careers in veterinary medicine, and a field trip to a physiological research laboratory. All fifteen students have presented final or to-date research results to fellow students, faculty mentors and faculty advisory committee. PRODUCTS: Fifteen students have presented final or to-date results of their research projects to fellow students, faculty mentors and faculty advisory committee. OUTCOMES: Through their research projects and the seminars throughout the summer, the students have had an opportunity to increase their awareness and develop an interest in using genomic approaches to address critical issues facing veterinary medicine and public health safety. All fifteen students completed their summer research project term, and some are continuing their research into the coming year. Evaluation surveys have been distributed to all program student and mentors to determine the specific successes of the program. The programs in the previous three years, which included a combined total of thirty students, have resulted in three students enrolling in graduate programs. DISSEMINATION ACTIVITIES: Fifteen students have presented final or to-date results of their research projects to fellow students, faculty mentors and faculty advisory committee. All fifteen students will present their research findings at the University of Minnesota College of Veterinary Medicine Research Days in March 2006. Some of the students' projects will result in scientific publications in peer reviewed journals and presentations at national meetings. FUTURE INITIATIVES: Future plans for the program include the continued efforts to attract another group of qualified students for participation in the program, to attract one or more students from other colleges of veterinary medicine, and to send students to the Merck Merial Symposium in 2006.

Impacts
Students learned how to conduct basic research. Through their research projects, seminars and field trip, the students have increased their awareness and training in the area of research. At least one student is considering graduate studies.

Publications

  • Variable Number Tandem Repeat Analysis for the Differentiation of Lawsonia intracellularis from Various Animal Species. N. Weber, D. Beckler, V. Kapur, C. Gebhart. University of Minnesota College of Veterinary Medicine Points of Pride Research Days, March 23, 2005.
  • MHC Class I Allele Frequency in the Appaloosa. S. Wefel, M. Rutherford. University of Minnesota College of Veterinary Medicine Points of Pride Research Days, March 23, 2005.
  • Gene Expression Alterations in Prior Disease. J. Wicklund, H. Abbassi, P. Skinner. University of Minnesota College of Veterinary Medicine Points of Pride Research Days, March 23, 2005.
  • Frequency of Glycogen Branching Enzyme Deficiency Allele in the Quarter Horse Population. J. Wiseman, M. Wagner, S. Valberg, J. Mickelson. University of Minnesota College of Veterinary Medicine Points of Pride Research Days, March 23, 2005.
  • Schurrer JA, Dee SA, Moon RD, Rossow KD, Mahlum C, Mondaca E, Otake S, Fano E, Collins JE, and Pijoan C. Spatial dispersal of porcine reproductive and respiratory syndrome virus-contaminated flies after contact with experimentally infected pigs. Am J Vet Res, Vol 65 No 9, Sept 2004.
  • Schurrer JA, Dee SA, Moon RD, Murtaugh MP, Finnegan CP, Deen J, Kleiboecker SB, and Pijoan C. Retention of ingested porcine reproductive and respiratory syndrome virus in house flies. Am J Vet Res September 2005; Vol. 66, No. 9; pg 1469-1656.
  • Characterization of antibiotic resistance in E. Coli from river systems in rural Chile. C.A. Angle, G. Gonzalez, E. Gesche, S. Ernst, G. Ramirez, and R.S. Singer. University of Minnesota College of Veterinary Points of Pride Research Days, March 23, 2005.
  • Pathogenesis of encephalomyocarditis and coxsackie viruses in xenotransplantation. J. Bryngelson, L. Brewer, M. Njenga. University of Minnesota College of Veterinary Medicine Points of Pride Research Days, March 23, 2005.
  • Immune Response to Porcine Reproductive and Respiratory Syndrome Virus: Serological Differentiation of Vaccinated from Field Virus-Infected Pigs. M. Carl, C. Johnson, M. Murtaugh. University of Minnesota College of Veterinary Medicine Points of Pride Research Days, March 23, 2005.
  • Microsatellite Instability in Canine Tumors. K. Griffin, E. McNiel, J. Mickelson. University of Minnesota College of Veterinary Medicine Points of Pride Research Days, March 23, 2005.
  • Simultaneous Assay for Xanthine and Uric Acid in Dalmation Urine and Serum. H. Handley, J. Lulich. A. Singh. University of Minnesota College of Veterinary Medicine Points of Pride Research Days, March 23, 2005.
  • Identification of gene expression alterations in brains of Alzheimer disease mice. B. Hardy, H. Abbassi, K. Ashe, P. Skinner. University of Minnesota College of Veterinary Medicine Points of Pride Research Days, March 23, 2005.
  • Growth Patterns of Feline Bladder Epithelial Cells in the Presence of Urine from Feline Interstitial Cystitis Cats. K. Kiefer, J. Lulich, C. Osborne, M. Rutherford, G. Flickinger, J. Hendrickson. University of Minnesota College of Veterinary Medicine Points of Pride Research Days, March 23, 2005.
  • Effect of Pasteurization Temperature on Immunoglobulin G Loss and Pathogen Viability in Bovine Colostrum. S. McMartin, S. Godden, J. Feirtag, R. Bey, L. Metezger. University of Minnesota College of Veterinary Medicine Points of Pride Research Days, March 23, 2005.
  • Interrupting the Manure Pathogen Cycle on Dairy Farms. D. Murphy, S. Wells. University of Minnesota College of Veterinary Medicine Points of Pride Research Days, March 23, 2005.
  • Intervention Strategies for on farm fly control. J. Schurrer, S. Dee, R. Moon, C. Pijoan. University of Minnesota College of Veterinary Medicine Points of Pride Research Days, March 23, 2005.
  • Linkage Analysis in X-linked Leonberger Polyneuropathy. J. Volinski, E. Patterson, J. Mickelson. University of Minnesota College of Veterinary Medicine Points of Pride Research Days, March 23, 2005.


Progress 10/01/03 to 09/30/04

Outputs
A total of fifteen students were selected as a result of a competitive process based on their research project proposals. Student proposals were reviewed and final selections were made by a faculty advisory committee. All students have been participating in summer research projects in fourteen separate labs. Also included in the experience have been a series of seminars and field trips, with sessions on ethics relating to animal use and clinical and applied research, journal clubs on applied and basic sciences, a panel presentation on alternate careers in veterinary medicine, and a field trip to a physiological research laboratory. Thirteen of the fifteen students have presented final or to-date research results to fellow students, faculty mentors and faculty advisory committee. PRODUCTS: Thirteen students have presented final or to-date results of their research projects to fellow students, faculty mentors and faculty advisory committee. Four students presented posters at the Merck Merial Veterinary Symposium in July 2004. (The Merck Merial Veterinary Symposium is a national symposium where research findings are presented and experiences shared among the years veterinary scholars and the invited veterinary faculty. Each student is asked to present a poster that describes their research question, method of approach to the problem and any results they may have at the time of the symposium. The students and faculty are also able to learn about the different programs taking place at vet schools across the US. The three primary goals of the meeting are to share strategies for program and scholar success, to develop collaborative relationships that facilitate this success, and to focus upon the research successes of student Scholars. Through this partnership of Merck, Merial and the veterinary schools, it is hoped that the positive experiences will stimulate some of the scholars to pursue a career in research.) OUTCOMES: Through their research projects and the seminars throughout the summer, the students have had an opportunity to increase their awareness and develop an interest in using genomic approaches to address critical issues facing veterinary medicine and public health safety. All fifteen students completed their summer research projects, and some are continuing their research into the coming year. Evaluations will be going out to all students and mentors within the next few weeks to determine the specific successes of the program. The programs in the previous two years, which included a combined total of fifteen students, have resulted in three students enrolling in graduate programs. DISSEMINATION ACTIVITIES: Thirteen students have presented final or to-date results of their research projects to fellow students, faculty mentors and faculty advisory committee. Four students did poster presentations at the Merck Merial Veterinary Symposium in July 2004. All fifteen students will present their research findings at the University of Minnesota College of Veterinary Medicine Research Days in March 2005. Some of the students projects will result in scientific publications in peer reviewed journals and presentations at national meetings. FUTURE INITIATIVES: Future plans for the program include the continued efforts to attract another group of qualified students for participation in the program, to attract one or more students from other colleges of veterinary medicine, and to send at least four additional students to the Merck Merial Symposium in 2005.

Impacts
Students learned how to conduct basic research. Through their research projects, seminars, field trips, and attendance at the Merck Merial Symposium, the students have increased their awareness and training in the area of research. At least one student is considering graduate studies.

Publications

  • Bryngelson J, Brewer L, Njenga M, Kirchhof N, Hering B, Myers S, Shaw D, Brown C. 2004. Pathogenesis of encephalomyocarditis and coxsackie viruses in xenotransplantation, Merck Merial Veterinary Scholars Symposium 5:46.
  • Carl M, Johnson C, Murtaugh M. 2004. Immune Response to Porcine Reproductive and Respiratory Symdrome Virus: Serological Differentiation of Vaccinated from Field Virus-Infected Pigs, Merck Merial Veterinary Scholars Symposium 5:64.
  • Handley H, Lulich J, Singh A. 2004. Simultaneous Assay for Xanthine and Uric Acid in Dalmation Urine and Serum, Merck Merial Veterinary Scholars Symposium 5:73.
  • Wiseman J, Valberg S, Mickelson J. 2004. Frequency of Glycogen Branching Enzyme Deficiency Allele in Quarter Horse Population, Merck Merial Veterinary Scholars Symposium 5:30.