Progress 10/01/00 to 06/30/15
Outputs
OUTPUTS: The purpose of this grant is to continue an established interdisciplinary reproductive, developmental and endocrine toxicology training program for education of predoctoral and postdoctoral candidates in biochemical, molecular, cellular and neurobehavioral aspects of reproductive, development and endocrine toxicology. The Univ of Illinois (UIUC) has a well-established Interdisciplinary Environmental Toxicology Program (IETP) that has been in existence since the mid-1980s. Seventeen faculty members from five colleges and nine departments (Molecular and Interactive Physiology, Chemistry, Animal Sciences, Microbiology, Food Science and Human Nutrition, Crop Sciences, Psychology, Electrical and Computer Engineering and Comparative Biosciences) serve as preceptors for students and postdocs in the training program. These faculty represent research disciplines ranging from neurobehavioral effects of environmental endocrine disrupters to molecular toxicology of the estrogen receptor. Ongoing research projects are directly related to the health-related areas outlined in the NIEHS Mission Statement, including developmental defects, sterility, breast and testicular cancers, chemical mimics of the hormone estrogen and identification of biomarkers for detection of human exposure to endocrine disrupters. A broad range of toxicology courses are available to upper level undergraduate and graduate students through the IETP. Courses are also available through a well-established Reproductive Biology Training Program. Predoctoral trainees take core courses in basic and systems toxicology and ethics in toxicology in addition to their departmental requirements. Postdoctoral fellows participate in independent research. All trainees attend weekly research seminars and present and discuss their research proposals and data each year. Selection is based upon candidate's academic success, relevance of proposed research to program goals, candidate's commitment, and advisor's support. Predoctoral and postdoctoral trainees receive up to three years of funding through the program. All research facilities are well equipped to support the diverse training required for this program and considerable collaboration between the faculty members already occurs. The Univ supports the Interdisciplinary Environmental Toxicology Program and individual laboratories through campus-wide research centers and facilities. The program is currently in its 11th year. A growing number of predoctoral students have received or are receiving training in the laboratories of the preceptors. Current preceptors include: Susan L. Schantz, PhD Director Jodi Flaws, PhD Associate Director, Indrani C. Bagchi, PhD Preceptor Milan K. Bagchi, PhD Preceptor, Duncan C. Ferguson, DVM, PhD Preceptor, William G. Helferich, PhD Preceptor Marie-Claude Hofmann, PhD Preceptor Elizabeth H. Jeffery, PhD Preceptor Benita S. Katzenellenbogen, PhD Preceptor John A. Katzenellenbogen, PhD Preceptor Ann M. Nardulli, PhD Preceptor Romana Nowak, PhD Preceptor Michael J. Plewa, Gregory Fruend, MD, Preceptor, Steven Boppart, MD, PhD preceptor, Janice Juraska, PhD Preceptor, Donna Korol, PhD Preceptor, Lori Raetzman, PhD Preceptor. PARTICIPANTS: Nothing significant to report during this reporting period. TARGET AUDIENCES: Nothing significant to report during this reporting period. PROJECT MODIFICATIONS: Nothing significant to report during this reporting period.
Impacts
The purpose of this interdisciplinary program is the education of predoctoral and postdoctoral fellows in biochemical, molecular, cellular and neurobehavioral research in reproductive, developmental and endocrine toxicology. Students trained in programs such as this will fill key environmental toxicology research positions in academia, industry and government in the future. For example, recent trainees to leave the program have accepted faculty positions at Universities such as Virginia Tech, at private contract labs such as Covance and at key government agencies such as the Food and Drug Administration.
Publications
- No publications reported this period
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Progress 10/01/08 to 09/30/09
Outputs
OUTPUTS: The purpose of this interdisciplinary program is the education of predoctoral and postdoctoral fellows in biochemical, molecular, cellular and neurobehavioral research in reproductive, developmental and endocrine toxicology. The program is currently in its 10th year. A growing number of predoctoral students have received or are receiving training in the laboratories of Drs. Jodi Flaws, Rex Hess, Benita Katzenellenbogen, John Katzenellenbogen, Janice Bahr, Michael Plewa, Paul Cooke, Humphrey Yao, Romana Nowak and Susan Schantz. Also, postdoctoral fellows have or are being trained in the laboratories of Drs. Ann Nardulli, Bill Helferich, Rex Hess, John Katzenellenbogen, and Benita Katzenellenbogen and Susan Schantz. Thus, in the 10 years of its existence the grant has benefited 11 different research labs in 6 different departments from three colleges. We have had three under-represented minority students enrolled as predoctoral trainees and one as a postdoctoral trainee. During the past year, a number of nationally recognized scientists visited our campus to present seminars in the toxicology seminar series. Students in our program are required to attend the toxicology seminar series each semester and must give a seminar presenting their own research once per year. In addition to the regular seminars, we hold a toxicology open house yearly with a high profile guest speaker and a poster session. Also, trainees in the program have formed their own journal club and meet monthly to discuss current publications of interest to the group. PARTICIPANTS: Susan L. Schantz, PhD Director Jodi Flaws, PhD Associate Director Janice M. Bahr, PhD Preceptor Indrani C. Bagchi, PhD Preceptor Milan K. Bagchi, PhD Preceptor Paul S. Cooke, PhD Preceptor Duncan C. Ferguson, DVM, PhD Preceptor Rex Hess, PhD, Preceptor William G. Helferich, PhD Preceptor Marie-Claude Hofmann, PhD Preceptor Elizabeth H. Jeffery, PhD Preceptor Benita S. Katzenellenbogen, PhD Preceptor John A. Katzenellenbogen, PhD Preceptor Ann M. Nardulli, PhD Preceptor Romana Nowak, PhD Preceptor Michael J. Plewa, PhD Preceptor Humphrey Yao, PhD Preceptor TARGET AUDIENCES: Not relevant to this project. PROJECT MODIFICATIONS: Not relevant to this project. TARGET AUDIENCES: The target audience is pre- and postdoctoral students in developmental, endocrine or reproductive toxicology. PROJECT MODIFICATIONS: Nothing significant to report during this reporting period.
Impacts
The purpose of this interdisciplinary program is the education of predoctoral and postdoctoral fellows in biochemical, molecular, cellular and neurobehavioral research in reproductive, developmental and endocrine toxicology. Students trained in programs such as this will fill key environmental toxicology research positions in academia, industry and government in the future. For example, recent trainees to leave the program have accepted faculty positions at Universities such as Virginia Tech, at private contract labs such as Covance and at key government agencies such as the Food and Drug Administration.
Publications
- No publications reported this period
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Progress 10/01/07 to 09/30/08
Outputs
OUTPUTS: The purpose of this interdisciplinary program is the education of predoctoral and postdoctoral fellows in biochemical, molecular, cellular and neurobehavioral research in reproductive, developmental and endocrine toxicology. The program is currently in its 9th year. A growing number of predoctoral students have received or are receiving training in the laboratories of Drs. Jodi Flaws, Rex Hess, Benita Katzenellenbogen, John Katzenellenbogen, Janice Bahr, Michael Plewa, Paul Cooke, Humphrey Yao, Romana Nowak and Susan Schantz. Also, postdoctoral fellows have or are being trained in the laboratories of Drs. Ann Nardulli, Bill Helferich, Rex Hess, John Katzenellenbogen, and Benita Katzenellenbogen and Susan Schantz. Thus, in the 9 years of its existence the grant has benefited 11 different research labs in 6 different departments from three colleges. We have had two under-represented minority students enrolled as predoctoral trainees and one as a postdoctoral trainee. During the past year, a number of nationally recognized scientists visited our campus to present seminars in the toxicology seminar series. Students in our program are required to attend the toxicology seminar series each semester and must give a seminar presenting their own research once per year. In addition to the regular seminars, we hold a toxicology open house yearly with a high profile guest speaker and a poster session. Also, trainees in the program have formed their own journal club and meet monlthly to discuss current publications of interest to the group. PARTICIPANTS: Susan L. Schantz, PhD Director Rex A. Hess, PhD Associate Director Janice M. Bahr, PhD Preceptor Indrani C. Bagchi, PhD Preceptor Milan K. Bagchi, PhD Preceptor Paul S. Cooke, PhD Preceptor Duncan C. Ferguson, DVM, PhD Preceptor Jodi A Flaws, PhD, Preceptor William G. Helferich, PhD Preceptor Marie-Claude Hofmann, PhD Preceptor Elizabeth H. Jeffery, PhD Preceptor Benita S. Katzenellenbogen, PhD Preceptor John A. Katzenellenbogen, PhD Preceptor Ann M. Nardulli, PhD Preceptor Romana Nowak, PhD Preceptor Michael J. Plewa, PhD Preceptor Humphrey Yao, PhD Preceptor TARGET AUDIENCES: Not relevant to this project. PROJECT MODIFICATIONS: Not relevant to this project.
Impacts
The purpose of this interdisciplinary program is the education of predoctoral and postdoctoral fellows in biochemical, molecular, cellular and neurobehavioral research in reproductive, developmental and endocrine toxicology. Students trained in programs such as this will fill key environmental toxicology research positions in academia, industry and government in the future. For example, recent trainees to leave the program have accepted faculty positions at Universities such as Virginia Tech, at private contract labs such as Covance and at key government agencies such as the Food and Drug Administration.
Publications
- No publications reported this period
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Progress 10/01/06 to 09/30/07
Outputs
OUTPUTS: This is an interdisciplinary training program in reproductive, developmental and endocrine toxicology which has as its goal the education of predoctoral and postdoctoral candidates in biochemical, molecular, cellular and neurobehavioral aspects of reproductive, development and endocrine toxicology. Seventeen faculty members from four colleges and seven departments (Molecular and Integrative Physiology, Chemistry, Animal Sciences, Microbiology, Food Science and Human Nutrition, Crop Sciences and Veterinary Biosciences) serve as preceptors. These faculty represent research disciplines ranging from neurobehavioral effects of environmental endocrine disrupters to molecular toxicology of the estrogen receptor. Ongoing research projects are directly related to the human health-related areas outlined in the NIEHS Mission Statement. A broad range of toxicology courses are available to trainees through the campus-wide Interdisciplinary Environmental Toxicology Program. Predoctoral
trainees take core courses in basic toxicology and ethics in toxicology and can choose from upper level graduate courses in reproductive and developmental toxicology, neurotoxicology, genetic toxicology and others in addition to their departmental requirements. Postdoctoral fellows participate in independent research. All trainees will attend weekly research seminars and present and discuss their research each semester. Attendance and presentation at local and national scientific meetings is strongly encouraged. Preference for funding is given to predoctoral trainees during their first or second year. Selection is based upon candidate's academic success, relevance of proposed research to program goals, candidate's commitment, and advisor's support. Predoctoral and postdoctoral trainees receive up to two years of funding through the program. All research facilities are well equipped to support the diverse training required for this program and considerable collaboration between the
faculty preceptors occurs. The University supports the Interdisciplinary Environmental Toxicology Program and individual laboratories through campus-wide research centers and facilities.
PARTICIPANTS: The participants on this project are 17 research training preceptors: Dr. Susan L. Schantz, Dr. Rex Hess, Dr. Paul Cooke, Dr. Jodi Flaws, Dr. Duncan Ferguson, Dr. Marie-Claude Hoffman, Dr. Indrani Bagchi and Dr. Humphrey Yao from the Department of Veterinary Biosciences, Dr. Janice Bahr and Dr. Romana Nowak from the Department of Animal Sciences, Dr. John Katzenellenbogen from the Department of Chemistry, Dr. Benita Katzenellenbogen, Dr. Milan Bagchi and Dr. Ann Nardulli from Molecular and Integrative Biology, Dr. Michael Plewa from Crop Sciences and Dr. William Helferich and Dr. Elizabeth Jeffery from Food Science and Human Nutrition.
Impacts
Pre- and postdoctoral trainees from this program, which is now in its eighth year, have gone on to successful jobs in academia, industry and government and continue to influence the field of toxicology through their research and scholarly publications as well as through their participation in training the next generation of toxicologists. Information about current and past pre- and postdoctoral trainees including their current job titles and affiliations is available at the program website: http://www.cvm.uiuc.edu/vb/nihtox/Templates/past_trainees.htm.
Publications
- No publications reported this period
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Progress 10/01/05 to 09/30/06
Outputs
The purpose of this interdisciplinary program is the education of predoctoral and postdoctoral fellows in biochemical, molecular, cellular and neurobehavioral research in reproductive, developmental and endocrine toxicology. The program is currently in its 7th year. A growing number of predoctoral students have received or are receiving training in the laboratories of Drs. Rex Hess, Benita Katzenellenbogen, John Katzenellenbogen, Janice Bahr, Michael Plewa, Paul Cooke, Humphrey Yao, Romana Nowak and Susan Schantz. Also, postdoctoral fellows have or are being trained in the laboratories of Drs. Ann Nardulli, Bill Helferich, Rex Hess, John Katzenellenbogen, and Benita Katzenellenbogen and Susan Schantz. Thus, in the 6.5 years of its existence the grant has benefited 11 different research labs in 6 different departments from three colleges. We have had two minority students enrolled as predoctoral trainees. One recently completed his PhD and started a position with the
Center for Disease Control (CDC). The other is in her fourth year of training and is currently visiting Emory University to conduct research with a faculty member there. During the past year, a number of nationally recognized scientists visited our campus to present seminars in the toxicology seminar series. Students in our program are required to attend the toxicology seminar series each semester and must give a seminar presenting their own research once per year. In addition to the regular seminars, we recently held a toxicology open house in which we invite previous graduates of our program returened to talk to current students and postdocs about their career paths since leaving our program. These presentations were a huge success and have provided valuable information about career opportunities to our trainees. Also, trainees in the program have formed their own journal club and for the past three years have been meeting biweekly at lunch time to discuss current publications of
interest to the group.
Impacts
The purpose of this interdisciplinary program is the education of predoctoral and postdoctoral fellows in biochemical, molecular, cellular and neurobehavioral research in reproductive, developmental and endocrine toxicology. Students trained in programs such as this will fill key environmental toxicology research positions in academia, industry and government in the future.
Publications
- No publications reported this period
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Progress 10/01/04 to 09/30/05
Outputs
The purpose of this interdisciplinary program is the education of predoctoral and postdoctoral fellows in biochemical, molecular, cellular and neurobehavioral research in reproductive, developmental and endocrine toxicology. The program was recently refunded and is currently in its 6th year. A growing number of predoctoral students have received or are receiving training in the laboratories of Drs. Rex Hess, Benita Katzenellenbogen, John Katzenellenbogen, Janice Bahr, Michael Plewa, Paul Cooke, Humphrey Yao and Susan Schantz. Also, postdoctoral fellows have or are being trained in the laboratories of Drs. Ann Nardulli, Bill Helferich, Rex Hess, John Katzenellenbogen, and Benita Katzenellenbogen. Thus, in the 5.5 years of its existence the grant has benefited 10 different research labs in 6 different departments from three colleges. We have had two minority students enrolled as predoctoral trainees. One recently completed his PhD and started a position with the Center
for Disease Control (CDC). The other is in her third year of training and has transitioned from the training grant to a toxicology scholars award. During the past year, a number of nationally recognized scientists visited our campus to present seminars in the toxicology seminar series. Students in our program are required to attend the toxicology seminar series each semester and must give a seminar presenting their own research once per year. In addition to the regular seminars, we recently instituted a new program talked Tox Talks in which we invite previous graduates of our program back to talk to current students and postdocs about their career paths since leaving our program. These presentations have been a huge success and have provided valuable information about career opportunities to our trainees. Also, trainees in the program have formed their own journal club and for the past three years have been meeting biweekly at lunch time to discuss current publications of interest to
the group.
Impacts
The purpose of this interdisciplinary program is the education of predoctoral and postdoctoral fellows in biochemical, molecular, cellular and neurobehavioral research in reproductive, developmental and endocrine toxicology. Students trained in programs such as this will fill key environmental toxicology research positions in academia, industry and government in the future.
Publications
- No publications reported this period
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Progress 10/01/03 to 09/30/04
Outputs
The purpose of this interdisciplinary program is the education of predoctoral and postdoctoral fellows in biochemical, molecular, cellular and neurobehavioral research in reproductive, developmental and endocrine toxicology. The program is currently in its 5th year and is continuing to grow. A growing number of predoctoral students have received or are receiving training in the laboratories of Drs. Rex Hess, Benita Katzenellenbogen, Janice Bahr, Michael Plewa, Paul Cooke and Susan Schantz. Also, postdoctoral fellows have or are being trained in the laboratories of Drs. Ann Nardulli, Bill Helferich, John Katzenellenbogen, and Benita Katzenellenbogen. Thus, in the 4.5 years of it existence the grant has benefited 9 different research labs in 6 different departments from three colleges. We have had two minority students enrolled as predoctoral trainees. One recently completed his PhD and started a position with the Center for Disease Control (CDC). The other is in her
second year of training and making excellent progress. During the past year, a number of nationally recognized scientists visited our campus to present seminars in the toxicology seminar series. Students in our program are required to attend the toxicology seminar series each semester and must give a seminar presenting their own research once per year. In addition to the regular seminars, we recently instituted a new program talked Tox Talks in which we invite previous graduates of our program back to talk to current students and postdocs about their career paths since leaving our program. These presentations have been a huge success and have provided valuable information about career opportunities to our trainees. Also, trainees in the program have formed their own journal club and for the past two years have been meeting biweekly at lunch time to discuss current publications of interest to the group. In April of 2003 our program underwent an external review process, which provided
excellent ideas for how we can strengthen and expand the program in the future.
Impacts
The purpose of this interdisciplinary program is the education of predoctoral and postdoctoral fellows in biochemical, molecular, cellular and neurobehavioral research in reproductive, developmental and endocrine toxicology. Students trained in programs such as this will fill key environmental toxicology research positions in academia, industry and government in the future.
Publications
- No publications reported this period
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Progress 10/01/02 to 09/30/03
Outputs
The purpose of this interdisciplinary program is the education of predoctoral and postdoctoral fellows in biochemical, molecular, cellular and neurobehavioral research in reproductive, developmental and endocrine toxicology. The program is currently in its 4th year and is continuing to grow. A growing number of predoctoral students have received or are receiving training in the laboratories of Drs. Rex Hess, Benita Katzenellenbogen, Janice Bahr, Plewa and Susan Schantz. Also, postdoctoral fellows have or are being trained in the laboratories of Drs. Ann Nardulli, Bill Helferich, John Katzenellenbogen, Rex Hess and Benita Katzenellenbogen. Thus, in the 3.5 years of it existence the grant has benefited 8 different research labs in 6 different departments from three colleges. We have had two minority students enrolled as predoctoral trainees. One recently moved off the training grant and onto a prestigious Toxicology Scholars Award, which will fund the last three years
of his graduate education. The other just began training during the current grant year. During the past year, a number of nationally recognized scientists visited our campus to present seminars in the toxicology seminar series. Students in our program are required to attend the toxicology seminar series each semester and must give a seminar presenting their own research once per year. In addition to the regular seminars, we recently we instituted a new program talked Tox Talks in which we invite previous graduates of our program back to talk to current students and postdocs about their career paths since leaving our program. These presentations have been a huge success and have provided valuable information about career opportunities to our trainees. Also, trainees in the program have formed their own journal club and for the past year have been meeting biweekly at lunch time to discuss current publications of interest to the group. In April of 2003 our program underwent an external
review process, which provided excellent ideas for how we can strengthen and expand the program in the future.
Impacts
The purpose of this interdisciplinary program is the education of predoctoral and postdoctoral fellows in biochemical, molecular, cellular and neurobehavioral research in reproductive, developmental and endocrine toxicology. Students trained in programs such as this will fill key environmental toxicology research positions in academia, industry and government in the future.
Publications
- No publications reported this period
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Progress 10/01/01 to 09/30/02
Outputs
The purpose of this interdisciplinary program is the education of predoctoral and postdoctoral fellows in biochemical, molecular, cellular and neurobehavioral research in reproductive, developmental and endocrine toxicology. The program is showing rapid progress with four predoctoral students already enrolled in the laboratories of Drs. Rex Hess, Benita Katzenellenbogen, Janice Bahr, and Susan Schantz. Also, 3 postdoctoral fellows are now established in the laboratories of Drs. Ann Nardulli, Bill Helferich and Benita Katzenellenbogen. Thus, the benefits of the grant are currently spread across 6 different research labs and 5 different departments. We have one minority student enrolled in the PhD. Program for the second year and we are planning a second recruitment trip in January. During the past semester, several scientists visited our campus to present seminars. Students in our program are required to attend the toxicology seminar series each semester as well as
other related seminars, such as the reproductive biology seminars. The following seminars were presented by outside speakers. The training program has retained one underrepresented minority fellow, Alex Rivera, who is now studying under Dr. Janice Bahr. Also, Christine Warnes has been assisting in Dr. Narduli's laboratory, helping to define regions of the progesterone receptor gene involved in estrogen responsiveness. Christine is of Native American ancestry. She was supported over the summer by a Merck Minority Summer Research Fellowship.
Impacts
(N/A)
Publications
- No publications reported this period
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Progress 10/01/00 to 09/30/01
Outputs
The Toxicology Training Program was funded by the National Institute of Environmental Health Sciences in July 2000 to establish an interdisciplinary reproductive, developmental and endocrine toxicology training program for the education of predoctoral and postdoctoral candidates in biochemical, molecular, cellular and neurobehavioral aspects of reproductive, developmental and endocrine toxicology. The University of Illinois (UIUC) has a well-established Interdisciplinary Environmental Toxicology Program (IETP) that has been in existence since the mid-1980's. The Program is now organized under The Environmental Council, a center that facilitates environmental education and research on the UIUC campus. Ten faulty members from four colleges and seven departments (Molecular & Interactive Physiology; Chemistry; Animal Sciences; Microbiology; Food Science & Human Nutrition; Crop Sciences; and Veterinary Biosciences) provide the core of the new training program.
These faculty represent research disciplines ranging from neurobehavioral effects of environmental endocrine disrupters to molecular toxicology of the estrogen receptor. Thus, ongoing research projects are directly related to health-related areas including developmental defects, sterility, breast and testicular cancers, chemical mimics of the hormone estrogen and identification of biomarkers for detection of human exposure to endocrine disrupters. A broad range of toxicology courses are already available to upper level undergraduate and graduate students through the IETP. Courses are also available through a well-established Reproductive Biology Training Program. Predoctoral Trainees will take core courses in biochemistry, endocrinology, basic toxicology, developmental toxicology, and reproductive and endocrine toxicology in addition to their departmental requirements. Postdoctoral fellows will participate in independent research. All trainees will attend weekly research seminars and
present and discuss their research proposals and data each semester. Attendance and presentation at local and national scientific meetings will be required. The University supports the IETP and individual laboratories through campus-wide research centers and facilities. Faculty members participating in this training program are: Dr. Rex Hess (Program Director), Dr. Indrani Bagchi, Dr. Milan Bagchi, Dr. Janice Bahr, Dr. Val Beasley, Dr. Paul Cooke, Dr. William Helferich, Dr. Benita Katzenellenbogen, Dr. John Katzenellenbogen, Dr. Ann Nardulli, Dr. Michael Plewa, and Dr. Susan Shantz (Associate Director). The program is showing rapid progress with four predoctoral students already enrolled in the laboratories of Drs. Rex Hess, Benita Katzenellenbogen, Janice Bahr, and Susan Schantz. Also, 3 postdoctoral fellows are now established in the laboratories of Drs. Ann Nardulli, Bill Helferich and Benita Katzenellenbogen. Thus, the benefits of the grant are currently spread across 6 different
research labs and 5 different departments. We have one minority student enrolled in the PhD. Program for the second year and we are planning a second recruitment trip in January of 2002.
Impacts
(N/A)
Publications
- No publications reported this period
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