Source: UNIVERSITY OF ARKANSAS submitted to NRP
AVIAN RESPIRATORY DISEASES: PATHOGENESIS, SURVEILLANCE, DIAGNOSIS AND CONTROL
Sponsoring Institution
National Institute of Food and Agriculture
Project Status
COMPLETE
Funding Source
Reporting Frequency
Annual
Accession No.
0184413
Grant No.
(N/A)
Cumulative Award Amt.
(N/A)
Proposal No.
(N/A)
Multistate No.
(N/A)
Project Start Date
Oct 1, 1999
Project End Date
Sep 30, 2005
Grant Year
(N/A)
Program Code
[(N/A)]- (N/A)
Recipient Organization
UNIVERSITY OF ARKANSAS
(N/A)
FAYETTEVILLE,AR 72703
Performing Department
POULTRY SCIENCE
Non Technical Summary
A. Corona viruses continue to be a major problem for the broiler breeder area of the poultry industry. A. Continued characterization and evaluation of isolates as to pathogenesis and protective abilitites may lead to improved vaccines.
Animal Health Component
(N/A)
Research Effort Categories
Basic
100%
Applied
(N/A)
Developmental
(N/A)
Classification

Knowledge Area (KA)Subject of Investigation (SOI)Field of Science (FOS)Percent
3113210110150%
3113220110150%
Goals / Objectives
1)Determine the pathogenesis and interactions of specific agents. 3)Develop new and improved methods for diagnosis, prevention, and control of avian respiratory diseases.
Project Methods
IBV OK 9.6 will continue to be evaluated for chickens. The virus and antiseia generated will be available to collaborators for additional characterization. Delaware IBV 072 vaccine will be evaluated as to protective ability against IBV OK 9.6 challenge.

Progress 10/01/99 to 09/30/05

Outputs
Avian respiratory disease continues to be a problem in poultry. Coronaviruses have historically been a problem for production broilers and broiler breeders. Viral variants have been of significant impact in the some poultry producing states. Surveillance efforts here in Arkansas for a variant strain of the Delaware virus showed that it was of low incidence. Other respiratory diseases of significance such as Mycoplasma have been and are still are problem in commercial and backyard, hobby flocks. A past study conducted to determine spread of Mycoplasma from vaccinated to unvaccinated birds revealed that there was spread. The other respiratory disease of significance is Laryngotracheitis. This disease has been of past concern and is still a problem. However, surveillance and fingerprinting have shown that the problems are still of a vaccine induced nature.

Impacts
A better understanding of viral and bacterial respiratory pathogens found in the field allows for better control efforts such as vaccination and Biosecurity efforts. Testing of new vaccines allows improvement of and/or development of additional vaccines to combat respiratory diseases in poultry.

Publications

  • No publications reported this period


Progress 01/01/04 to 12/30/04

Outputs
There is a continued effort to identify flocks with respiratory disease in NW Arkansas and determine the causative agent. The disease , Infectious Bronchitis (IBV), continues to be a problem for broiler breeders resulting in morbidity, reduced egg production, and educed egg quality. The bacteria, Mycoplasma, has also been a problem for many broiler flocks. Evalaution of IBV isolates as to the pathogenic effects should be of value in better understanding the virus and developing control and/or vaccination strategies.

Impacts
A better understanding of the respiratory viruses of poultry can lead to better control methods and/or vaccination techniques or vaccines.

Publications

  • No publications reported this period


Progress 01/01/03 to 12/31/03

Outputs
There is a continued effort to identify flocks with respiratory disease in NW Arkansas and determine the causative agent. The disease , Infectious Bronchitis, continues to be a problem for broiler breeders resulting in morbidity, reduced egg production, and educed egg quality. Evalaution of isolates as to the pathogenic effects should be of value in better understanding the virus and developing control and/or vaccination strategies.

Impacts
A better understanding of the respiratory virusesof poultry can lead to better control methods and/or vaccination techniques or vaccines.

Publications

  • No publications reported this period


Progress 01/01/02 to 12/31/02

Outputs
Surveys were attempted in the commercial industry. There was extreme difficulty with the consistency of collection techniques used in the industry coupled with the seasonality of the appearance of respiratory disease. A comparable study with the table egg industry was conducted to determine the efficacy of a Mycoplasma eradictaion program using a commercial vaccine. The mycoplasma study showed promising results with regard to Biosecurity improvements and animal health and production. Additional studies are under consideration.

Impacts
New strains of Infectious bronchitis continue to emerge. better protection of birds can only be accomplished with continued studies on the effects of the disease in birds.

Publications

  • No publications reported this period


Progress 01/01/01 to 12/31/01

Outputs
Infectious Bronchitis isolates from the field and laboratory stocks will be compared for pathogenicity in broilers and/or specific pathogen free chickens. An epidemiological survey of the extent of the disease will be conducted using serological profile data.

Impacts
New strains of Infectious bronchitis continue to emerge. better protection of birds can only be accomplished with continued studies on the effects of the disease in birds.

Publications

  • No publications reported this period


Progress 01/01/00 to 12/31/00

Outputs
This study is currently in progress. Various isolates of Infectious Bronchitis will be compared as to pathogenicity in broiler and/or specific pathogen free chickens. A serological survey will be conducted to determine the extent of various strains of Infectious Bronchitis in Arkansas chickens in Northwest Arkansas. Additional isolates will be obtained as needed from affected commercial broilers for use in comparions.

Impacts
New strains of infectious bronchitis continue to emerge and need to be evaluated as to the effects in birds so better protection can be accomplished via vaccination.

Publications

  • No publications reported this period


Progress 01/01/99 to 12/31/99

Outputs
Infectious bronchitis O72 was isolated and various tests were performed. Tests performed included: ELISA, virus neutralization, and FA techniques. In addition, cross-protection/challenge studies were conducted in specific pathogen free poultry. Additional studies are proposed to study the pathogenesis of the virus. Since this is a new project the data collected is limited and incomplete.

Impacts
New strains of infectious bronchitis continue to emerge and need to be evaluated as to the effects in birds so better protection can be accomplished via vaccination.

Publications

  • No publications reported this period